Biologyarticle2026-10-28

Separable roles for Microprocessor and its cofactors ERH and SAFB1/2 during microRNA cluster assistance

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Abstract

Results of the smallRNA analysis pipeline used in "Separable roles for Microprocessor and its cofactors ERH and SAFB1/2 during microRNA cluster assistance". 20251028_mirbase_results.tar.gz : GZIP archive of the analysis pipeline results. NOTE that full genome alignment BAMs from the off-target filtering step and intermediate FASTQ files are not in this archive due to space contraints but are available from the authors on request). mirna_clusters_wang_et_al.tsv: GRCh38 coordinates of miRNA clusters from Wang et al., 2016 kim_et_al_2021_primirna_ce.tsv: Cleavage efficiency scores from Kim et al., 2021, Supp Table S6-2 mirbase_hsa.sorted.gff3.gz + .tbi: miRBase annotation GFF3, sorted, bgzipped and tabixed hsa.sorted.gff3.gz + .tbi: mirgenedb annotation GFF3, sorted, bgzipped and tabixed 20251029_ERHSAFB_paper_analysis.ipynb: analysis iPython notebook for creating the paper figures

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View paper (DOI)Open access versionOpenAlexZenodo (CERN European Organization for Nuclear Research)Published 2026-10-28

Authors: Renfu Shang, Seungjae Lee, Stefan Ludwig Ameres, Eric C. Lai

Institutions: University of Vienna, Memorial Sloan Kettering Cancer Center