Health & Medicinearticle2026-10-06

When the fat is missing: a fat-free spindle cell lipoma in a young woman

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Abstract

Dear Editor, Spindle cell lipoma (SCL) is a benign adipocytic neoplasm first characterized by Enzinger and Harvey, classically arising in the posterior neck, shoulder, and upper back of middle-aged to older men. Histologically, it is defined by a variable admixture of mature adipocytes, bland spindle cells, rope-like collagen, and myxoid matrix. The adipocytic component, however, may be minimal or entirely absent, creating a diagnostically deceptive low-fat or fat-free phenotype. [...].

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View paper (DOI)Open access versionOpenAlexDermatology ReportsPublished 2026-10-06

Authors: Maria Elisabetta Greco, Kiran Javaid, Shaunt Mehdikhani, Izadora Lapenda, Dan Rolando Lopez, Madeline Tchack, Bassem Rafiq, Noah Musolff, Babar K Rao

Institutions: Rowan University, Universidad Autónoma de Nuevo León, Cornell University, Sapienza University of Rome, Johnson University, University of Monterrey