Climate & Environmentarticle2026-09-01

ER stress promoted MAMs formation and ER-Mito Ca2+ transfer: implication for fluoride-induced hippocampal neuronal injury and cognitive deficits in mice.

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Abstract

transfer via the IP3R1/Grp75/VDAC1 complex and provided a potential therapeutic target for the treatment of fluoride-associated neurotoxicity and neurobehavioral disorders.

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View paper (DOI)OpenAlexPubMedPublished 2026-09-01

Authors: Siman Lin, LuYang Cao, Yuzhe Zhou, Shengdan Liu, Yue Yan, Qiwei Zhang, Quan Yuan, Yufei Gao, Ge Du, Jun Hu, Dongmei Wang, Hua Fan

Institutions: Henan University of Science and Technology, Luoyang Institute of Science and Technology, Luoyang Central Hospital Affiliated to Zhengzhou University, First Affiliated Hospital of Henan University of Science and Technology, Luoyang Orthopedic-Traumatological Hospital of Henan Province