Luoyang Orthopedic-Traumatological Hospital of Henan Province

Experimental evolution reveals biphasic adaptation of Bacillus subtilis to long-chain fatty acid stress

Gram-positive bacteria like Bacillus subtilis are typically sensitive to long-chain fatty acids (LCFAs), which serve as both nutrients and antimicrobials, posing an ecological paradox regarding their survival in lipid-rich environments. We experimentally evolved B. subtilis for ~...

Predictive value of perioperative hypothermia for postoperative muscular calf vein thrombosis after total knee arthroplasty: a retrospective cohort study

Abstract Objective To investigate the association between perioperative hypothermia and postoperative muscular calf vein thrombosis (MCVT) in patients undergoing total knee arthroplasty (TKA), and to evaluate the predictive performance of perioperative core temperature indicators...

ER stress promoted MAMs formation and ER-Mito Ca2+ transfer: implication for fluoride-induced hippocampal neuronal injury and cognitive deficits in mice.

transfer via the IP3R1/Grp75/VDAC1 complex and provided a potential therapeutic target for the treatment of fluoride-associated neurotoxicity and neurobehavioral disorders.