Health & Medicine
Low evidenceReview
Review examines why children often receive medicines outside official labels
This review examines off-label prescribing in children, meaning medicines used outside the terms of their official approval. It argues that such prescribing is not automatically inappropriate, but that its acceptability depends on the available evidence, the clinical setting, and safety monitoring. The article also describes continuing delays, incomplete studies, and a lack of suitable child-specific formulations.
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