Research Briefs

Biochemistry, Genetics and Molecular Biology · Molecular Biology

Muscle Physiology and Disorders

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Abstract editorial illustration accompanying the article: New analysis finds survival in Duchenne muscular dystrophy has improved over time
Biology
High evidenceReview

New analysis finds survival in Duchenne muscular dystrophy has improved over time

This systematic review and meta-analysis examined survival trends among more than 13,000 people with Duchenne muscular dystrophy across 53 studies. Survival was longer in studies of patients receiving home mechanical ventilation, and survival estimates improved over time, but treatment associations cannot establish that a particular treatment caused longer life.

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Abstract editorial illustration accompanying the article: Removing a key muscle-scar cell changes fat and scar after rotator cuff tears in mice
Biology

Removing a key muscle-scar cell changes fat and scar after rotator cuff tears in mice

A new study in mice tests what happens when fibroadipogenic progenitors—a cell type linked to both healing and degeneration—are depleted before injury. The approach reduced muscle scarring in both a rotator cuff tear model and a muscle tissue loss model, but only the rotator cuff tear model showed less fat buildup and better shoulder function.

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