Medicine · Endocrinology, Diabetes and Metabolism

Diet, Metabolism, and Disease

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Abstract editorial illustration accompanying the article: Review finds uncertain link between artificial sweeteners and bladder cancer
Health & Medicine
Moderate evidenceReview

Review finds uncertain link between artificial sweeteners and bladder cancer

Researchers combined results from 17 observational studies involving 22,438 people to examine artificial sweetener use and bladder cancer risk. The analysis found a borderline overall association, but the studies differed substantially and showed signs of possible publication bias. This research shows an association, not proof that artificial sweeteners cause bladder cancer.

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Abstract editorial illustration accompanying the article: Study finds early-life sugar rationing is linked to slower aging and lower mortality
Health & Medicine
High evidenceReview

Study finds early-life sugar rationing is linked to slower aging and lower mortality

Researchers analyzed UK Biobank participants to study whether sugar exposure in the first 1,000 days of life is associated with aging-related health outcomes later. They report that early-life sugar rationing was associated with lower incidence of hallmark-related disease and lower all-cause mortality, along with indicators of younger biological age. These are observational associations and do not prove that changing sugar intake would produce these outcomes.

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