Yunnan University

Exploration and practice of a DeepSeek‑enhanced, scenario‑based teaching model integrated with a multidisciplinary team approach in gastroenterology residency training

The first year of standardised residency training is a critical transition from medical student to clinical practitioner, during which trainees struggle to integrate theoretical knowledge with clinical competencies. Traditional teaching often lacks active learning and authentic c...

Divergent Forest Cover Changes Dominate Inter‐Model Spread in Near‐Surface Wind Speed Trends Over China

Abstract Near‐surface wind speed (NSWS) regulates the intensity of land‐atmosphere fluxes and the viability of wind energy systems, playing a pivotal role in human adaptation to climate change. However, at the current stage, global climate models exhibit a wide inter‐model spread...

Spatiotemporal Variation of Vegetation and Its Responses to Climate Change in Pakistan

Abstract Changes in vegetation cover and its relationship with climate factors are crucial for ecosystem stability, especially in arid and semiarid regions like Pakistan. However, the impact of temperature and precipitation fluctuations on vegetation dynamics in these regions rem...

Electron transfer kinetics and molecular structural basis of dissolved black carbon as an electron shuttle

Dissolved black carbon (DBC) serves as a crucial electron shuttle in various biogeochemical cycles owing to its highly mobile and redox-active nature. Prior work on DBC electron-shuttling has focused on thermodynamic metrics—electron donating capacity (EDC) and electron accepting...

2-Alkynyl-1-Naphthoate:A Reactive and Base-TolerantLeaving Group for Gold(I)-Catalyzed Glycosylation

Abstract 2-Alkynyl-1-naphthoate is disclosed as a reactive, base-tolerant leaving group for gold(I)-catalyzed glycosylation. Relocating the alkyne from C8 to C2 reduces steric congestion, facilitating donor preparation while preserving the anomeric ester under saponification cond...

Electrode placement effects on Joule heating and thermal uniformity in an AC zinc-smelting furnace

The steady electrothermal behavior of AC zinc-smelting furnaces is governed by current redistribution and Joule-heat localization, which directly affect bath-temperature uniformity and refractory thermal loading. A three-dimensional one-way coupled electromagnetic-thermal-flow mo...

Lost balance: synergy-redundancy dysfunction in Alzheimer’s disease

<title>Abstract</title> Alzheimer’s disease (AD) is the most common neurodegenerative disorder, yet reliable early biomarkers are still lacking, which greatly hinders timely intervention for AD. This study employed an integrated information decomposition framework to systematical...

Fe(III)-MediatedOxidative [5 + 1] Cyclization forthe Highly Site-Selective Synthesis of Functionalized Quinoline Derivatives

Abstract We describe a method for the construction of highly functionalized quinoline derivatives from enaminones via an oxidative [5 + 1] cyclization. A plausible mechanism may involve a cascade sequence including single-electron transfer (SET), radical Michael addition, elimina...

Perylenediimide Halogen Substitution-Modulated Photochromism and Photocatalytic Activity in Metal−Organic Frameworks

Abstract Perylenediimides (PDIs), which feature strong visible-light absorption, π-electron-deficient planes, and photochemical characteristics, offer a versatile platform for developing tunable and efficient metal−organic framework (MOF) materials through modulation of their bay...

Cross-sectional associations of generative AI acceptance with self-efficacy and well-being among students recruited from seven Chinese universities

Generative artificial intelligence (AI) is increasingly used in higher education, but its associations with students’ broader psychological outcomes remain uncertain. This cross-sectional study examined generative AI acceptance, general self-efficacy, and well-being among 495 stu...

Atmospheric Blocking Pattern as the Primary Driver of Subseasonal Greenland Ice Sheet Summer Melt Variability

ABSTRACT The anomalous summer melting of the Greenland Ice Sheet (GrIS) is one of the key signals of ongoing climate system changes. The complex spatiotemporal characteristics of GrIS and its impacts on global sea‐level rise have attracted increasing attention. Although previous...

AgEuPS4: Unlocking the CentrosymmetricShackle of Rare-Earth Thiophosphates via Microscopic Distortion Cascadingfor Enhanced Second-Harmonic Generation Response

Abstract Breaking the rigid centrosymmetric (CS) shackles of rare-earth thiophosphates remains a significant challenge for designing high-performance mid-to-far-infrared (MFIR) nonlinear optical (NLO) materials. Herein, using the CS LiEuPS4 (I41/acd) as the structural template, a...

Increasing Climate Constraint on Vegetation Productivity Under Rising CO 2 in Northeast Asia

Abstract Elevated atmospheric CO 2 enhances vegetation productivity through direct physiological and indirect climate‐mediated pathways. However, how the balance between these mechanisms evolves under continued CO 2 rise remains unclear. Here, we use CMIP6 Earth system models to...

Healing intervention for improving the efficiency and stability of tandem devices on industrial textured silicon

Monolithic perovskite/silicon tandem solar cells are widely regarded as the next-generation, low-cost, high-efficiency photovoltaic technology. However, achieving high-quality wide-bandgap perovskite top cells on industrial textured silicon, particularly using hybrid two-step dep...

Unlocking biological insight from single-cell data with an interpretable dual-stream foundation model

Abstract Deep learning foundation models are revolutionizing single-cell biology, yet learning holistic and discriminative representations from complex, high-dimensional data remains a central challenge. Although Transformer-based single-cell language models have shown significan...

Intra‐Bacterial Supramolecular Assembly of Peptide With RNA Activates MRI/Fluorescence Imaging and Avoids Drug Resistance

ABSTRACT Multidrug‐resistant Gram‐negative bacteria present a critical challenge for both diagnosis and therapy because diagnostic and therapeutic molecules have difficulty entering Gram‐negative bacteria, and these molecules can also be expelled by bacteria using efflux pumps. H...

Microglial immunometabolism in Alzheimer's disease: A stage-resolved trajectory from adaptive remodeling to the metabolic paradox

Microglia are central regulators of the cellular phase of Alzheimer's disease (AD). Under chronic exposure to amyloid-β, pathological tau, and aging-associated bioenergetic decline, these cells undergo immunometabolic remodeling that may initially be adaptive. As stress persists,...

Impact of ozone pollution on gross primary productivity during a large-scale emission reduction: Implications for strengthening carbon sink over megacity clusters in China

Ozone (O 3 ) pollution poses a significant threat to plant growth and diminishes ecosystem carbon sequestration capacity in China, representing a critical challenge to achieving “dual carbon” goals. A large-scale emission reduction that occurred during the Coronavirus disease 201...

Heavy‐Halide Coordination and Lattice‐Confined Molecular Alignment Enable Giant Birefringence in Hybrid Metal Halides

ABSTRACT High‐birefringence materials are essential for polarization optics, yet it remains difficult to translate anisotropic molecular building blocks into a strong directionally accumulated crystal‐scale optical anisotropy. Here, we establish a hybrid metal halide engineering...

Glymphatic-meningeal lymphatic dysfunction drives remote organ injury after aneurysmal subarachnoid hemorrhage: a unified neuroimmune framework and time-stratified therapeutic roadmap

Aneurysmal subarachnoid hemorrhage (aSAH) confers substantial mortality and morbidity driven not only by primary brain injury but also by systemic remote organ complications across the pulmonary, cardiac, renal and gastrointestinal systems. Despite growing recognition of neuroimm...