Yunnan University

All-solid-waste modified phosphogypsum-based backfill: Synergistic hydration, contaminant immobilization, and environmental assessment

Large-scale use of solid-waste-modified phosphogypsum (PG) backfill is vital for sustainable mining, but its hydration and contaminant immobilization mechanisms remain unclear. This study systematically reveals the multi-scale synergy, links mix design, microstructure, and macro-...

SIL1 modulates Reelin signaling during cortical neuron migration

Abstract SIL1 , a nucleotide exchange factor for the endoplasmic reticulum chaperone BiP, primarily binds nascent polypeptides to facilitate proper protein folding. It is a causative gene of Marinesco-Sjögren syndrome (MSS). Previous studies have indicated that SIL1 dysfunction d...

Impurities and defects in Czochralski silicon: mechanisms of their effects on carrier lifetime, power conversion efficiency, and resistivity uniformity

Monocrystalline silicon grown by the Czochralski (CZ) method is the dominant material for crystalline silicon solar cells; in this material, impurities and defects directly determine wafer quality and device performance by governing three core metrics: minority carrier lifetime,...

Evaluation of Atractylodes macrocephala Koidz Extract as a Multi-Functional Natural Ingredient for Skin Barrier Repair

Epidermal barrier damage triggers sensitive skin disorders. Synthetic skin repair agents frequently incur irritation, whereas medicinal and edible herbal ingredients offer milder alternatives. As a traditional Chinese medicinal herb, Atractylodes macrocephala Koidz remains inadeq...

Metabolic Engineering of Saccharomyces cerevisiae for Flavonoid Synthesis from Acetate

Abstract Acetate is a sustainable C2 feedstock derived from CO2 electroreduction, but its conversion to complex natural products is constrained by impaired cell growth and poor metabolic compatibility. Adaptive laboratory evolution generated an evolved Saccharomyces cerevisiae st...

Homework Responsibility and Parent–Adolescent Communication: Maternal and Paternal Associations with Academic and Psychological Adjustment Among Chinese Adolescents

Responsibility for homework and parent–adolescent communication may have different associations with adolescent adjustment. Using two waves of the China Education Panel Survey (2013–2015), we examined these parent-specific behaviors in outcome-specific analytic samples ranging fr...

Development of a New Analytical Model for Hysteretic Behavior of Precast Segmental Self‐Centering Pier Columns

ABSTRACT This paper presents a comprehensive analytical model for predicting the hysteretic behavior of precast segmental self‐centering (PSC) pier columns with different energy dissipation (ED) device arrangements. Three typical PSC pier configurations are considered: no energy...

Large Electrostrain and High Optical Transmittance via Oxygen Octahedron Rotation Disordering in KNN Ceramics

ABSTRACT Lead‐free K 0.5 Na 0.5 NbO 3 (KNN)‐based ceramics are promising candidates for multifunctional electronic materials. Nevertheless, the synergistic optimization of electrostrain and optical transmittance in KNN polycrystalline ceramics remains a critical challenge, owing...

Liver regeneration governed by zonated PIEZO1 mechanotransduction

Mechanical forces are recognized as regulators of organ development, homeostasis, and regeneration, yet how physical cues are sensed in a region-specific manner within the liver remains unclear. In a Science article, Zhang and colleagues identify DPP4-positive zone 2 hepatocytes...

Dynamic event-triggered adaptive cooperative control for robotic manipulator with output constraints and model uncertainties

This paper introduces an adaptive fuzzy-based dynamic event-triggered adaptive cooperative control to address the challenge of achieving high-performance control for robotic manipulators under model uncertainties and output constraints. This strategy designs a signal-processing-b...

Revealing the diurnal spatiotemporal dynamics and drivers of urban traffic congestion resilience

Urban traffic congestion imposes recurrent stress on urban transport systems and varies substantially across the day. This study conceptualises urban traffic congestion resilience (UTCR) as an hourly proxy state under recurrent congestion conditions and develops an integrated roa...

Reversible Inhibition of Ammonia Monooxygenase by 1,9-Decanediol Triggers a RegB-RegA-Associated Energy Crisis and Stress Response in Nitrosomonas europaea

Abstract 1,9-decanediol, a rice-derived biological nitrification inhibitor (BNI) suppresses soil nitrification and nitrous-oxide emissions, but the mechanisms of action against ammonia-oxidizing bacteria remain unclear. Combining physiology and transcriptomics in Nitrosomonas eur...

Tunable Noncovalent Interactions for Stereodivergent Organo/Metal Dual Catalysis: Asymmetric Allenylation of Both 3-Alkyl and 3-Aryl Oxindoles

Abstract The development of advanced catalytic paradigms for the precise synthesis of all stereoisomers of chiral molecules has long been an important yet challenging pursuit. Organo/metal dual catalysis represents a powerful platform for stereodivergent construction of vicinal s...

Identification of rainfall-activated multi-indicator pollution pulses and lagged responses in Erhai Lake based on continuous water quality monitoring

Rainfall runoff can activate non-point source pollution and generate short-term water-quality anomalies in plateau lake basins, but event-scale multi-indicator responses remain difficult to identify using conventional mean-based assessments. Here, water-quality records available...

Scalable quaternary topological insulator for low-power spintronics

Topological insulators (TIs) with spin-momentum-locked surface states exhibit high charge-to-spin (C2S) conversion efficiency. However, binary and ternary TIs are constrained by a narrow tunable composition window for their insulating bulk states, which limits spintronic performa...

Emerging roles of long non-coding RNA CASC2 in tumor chemoresistance – a review

Malignant tumors remain a leading cause of global mortality, and the development of chemoresistance represents a major obstacle to effective cancer treatment. Long non-coding RNAs (lncRNAs) are important regulators of tumor progression and therapeutic response. Cancer susceptibil...

Low dose methotrexate enhances lymphocytic JAM-A expression in rheumatoid arthritis

Objectives Endothelial Junction Adhesion Molecule A (JAM-A) functionally manages immune cell infiltration via tight junctions during the pathological development of human immune diseases. However, the expression and function of JAM-A on peripheral lymphocytes are yet to be well u...

Does international collaborative R&D expand the boundaries of regional low-carbon innovation?

Amid intense market competition, this study examines how international collaborative R&D influences the boundaries of regional low-carbon innovation. Using the “Behavior-Capability-Outcome” analytical framework and provincial panel data for China’s manufacturing industry from 201...

A polyphyodont, semiaquatic eutriconodontan mammal from the Early Cretaceous of China

Diphyodonty (the presence of two generations of teeth) characterizes extant mammals and has long been regarded as pivotal to the evolution of other mammalian traits, including precise occlusion and determinate growth. Nevertheless, our understanding of the pattern of dental repla...

Huangqi Guizhi Wuwu Decoction Ameliorates Cachexia in Lung Cancer Mice Through Regulating Amino Acid Metabolism: Insights From Transcriptomics, Metabolomics and Experimental Validation

ABSTRACT The effects and mechanisms of Huangqi Guizhi Wuwu Decoction (HGWD) in cancer cachexia remain unclear. We generated an in vivo cachexia model by implanting Lewis lung carcinoma cells into mice and treated animals with HGWD. We evaluated muscle function using grip strength...