Xi'an Jiaotong University

Flt3-dependent mitochondrial transfer from macrophages alleviates heart failure after myocardial infarction through SEC22B de-ISGylation

Abstract Fms-related receptor tyrosine kinase 3 (Flt3) is upregulated in ischemic hearts, yet its macrophage-specific role in post-ischemic remodeling remains unclear. Here, we identify macrophages as the predominant Flt3-expressing cells in the infarcted heart and demonstrate th...

Experimental study on plasma-assisted atomization characteristics of n-Dodecane sprays

In response to the global demand for low-carbon transportation, enhancing fuel combustion efficiency is essential to reducing emissions. In high-temperature and high-pressure combustion chambers, the extremely short residence time hinders effective atomization and secondary dropl...

CTCF-FXN regulatory axis plays critical roles in clinical assessments and disease progression of primary open-angle glaucoma

Primary open-angle glaucoma (POAG) is an irreversible ophthalmic disease that is the leading cause of blindness. Oxidative stress (OS) is considered an important contributor to POAG pathogenesis. However, its mechanism of action in POAG remains vague. FXN was identified as a cand...

Cordwood space-coiling metasurface and its frequency band control method for noise reduction

Following the principles of acoustics, designing building blocks with different functions and constructing acoustic metasurfaces through block splicing is of practical importance in engineering due to its advantages of quick installation, wide application, and reusability. In thi...

Rapid inverse design of large-scale freeform meta-optics with the neighborhood-attention transformer

Abstract Metasurfaces are progressively reshaping traditional optical paradigms and pushing the boundaries in complex applications where compact designs are essential. However, the design of metasurfaces demands substantial computational resources to numerically solve Maxwell's e...

Chronic Inflammation, Fibrotic Remodeling, and Regenerative Failure in Duchenne Muscular Dystrophy: Mechanisms and Therapeutic Opportunities

Duchenne muscular dystrophy (DMD) is an X-linked disorder initiated by dystrophin deficiency, but disease progression reflects more than sarcolemmal fragility. Recurrent myofiber injury sustains sterile inflammation through damage-associated innate immune signaling and downstream...

Degradation-Informed Resource Recovery of Spent Graphite Anodes for Sustainable Lithium-Ion Battery Recycling

Abstract As lithium-ion batteries enter the terawatt-hour era, spent graphite can no longer be treated as a low-value residue within metal-centered recycling schemes. The central challenge is not simply impurity removal but the misrecognition of degradation itself. Interlayer exp...

Out-of-distribution challenges in intelligent fault diagnosis: a survey of generalization and detection

Deep learning (DL)-based intelligent fault diagnosis (IFD) has achieved strong performance in mechanical systems, but its reliability can deteriorate when deployment data differ from the training distribution because of changes in operating conditions, equipment, sensing environm...

Over 20% Efficiency in As–Cast Organic Solar Cells Enabled by Flory–Huggins Parameter Engineering

ABSTRACT The realization of high–efficiency as–cast organic solar cells (OSCs) represents a key step toward simplified processing and scalable fabrication for commercialization. However, achieving high–performance as–cast devices remains challenging because it demands delicate ba...

Catalytic hydrothermal liquefaction of chrome-tanned leather scrap: Bio-oil upgrading, chromium migration and recovery of chromium-containing product

Chrome-tanned leather scrap (CLS) is a hazardous solid waste rich in protein and chromium, posing environmental risks while offering significant resource recovery potential. In this study, an integrated catalytic hydrothermal liquefaction (HTL) strategy was developed to couple bi...

Compact low-voltage waveplate-free burst-mode EO Q-switched Nd:YAG laser based on a thermally self-biased PIN-PMN-32PT crystal

We demonstrate a compact burst-mode electro-optically Q-switched Nd:YAG laser using a thermally self-biased PIN-PMN-32PT relaxor ferroelectric crystal. The crystal exhibited a half-wave voltage of 490 V under transverse EO modulation, which is substantially lower than that of con...

High‐Performance Violet Phosphorene‐Based Device via Tellurium Doping‐Induced Contact Resistance Reduction

ABSTRACT Two‐dimensional materials have attracted much attention in various research fields. The phosphorene structures with various allotropes, another type of elemental 2D materials after graphene, have been demonstrated to have unique optoelectronic and photoelectronic propert...

Magnetoreceptor Promotes Hepatocellular Carcinoma Development and Blunts Sorafenib‐Induced Ferroptosis by Regulating Iron Homeostasis

ABSTRACT Iron homeostasis plays a critical role in the pathogenesis and therapeutic management of hepatocellular carcinoma (HCC). Magnetoreceptor (MagR), also known as iron‐sulfur cluster assembly protein 1 (ISCA1), is a conserved protein maintaining iron homeostasis, plays an un...

Bio‐Memristor Based on Clinical Bile Samples: A Proof‐of‐Concept Pilot Study for Detection of Gallbladder Cancer

ABSTRACT Gallbladder cancer (GBC) is the most common malignant tumor of the biliary system, and the 5‐year survival rate of GBC patients is only 5% due to delayed diagnosis. The sensitivity and specificity of existing clinical testing equipment for gallbladder malignancy remain i...

Percolation‐Driven β ‐Relaxation Enables Resonant Acceleration of Crystallization in Amorphous Phase‐Change Materials

ABSTRACT Amorphous phase‐change materials enable fast and reversible switching in optical and electronic devices, yet crystallization kinetics are still controlled primarily through empirical thermal protocols. Here we identify a microscopic picture governing crystallization in t...

Major adverse cardiac events and mortality associated with ADHD and its treatment in adults with type 2 diabetes: a multi-national cohort study

Abstract Background Attention-deficit/hyperactivity disorder (ADHD) has been linked to elevated risk of type 2 diabetes (T2D). However, the impact of ADHD and ADHD medication use on prognosis and health outcomes in T2D remains unclear. This study investigates the associations of...

A dynamic adaptive multi-source aggregated transfer learning framework for individual thermal comfort prediction

Occupants’ thermal comfort is critical for building operation and energy management. However, thermal comfort is influenced by multiple factors and changes dynamically, making accurate prediction challenging. As a result, existing methods face key challenges, including limited ac...

Photovoltaic-phase change material systems: A review from thermal managements to system optimizations

This article starts from the core issues of photovoltaic thermal management, systematically reviews the mechanism of temperature's impact on photovoltaic efficiency. The analysis compares active and passive cooling technologies to highlight the distinct advantages of phase change...

Gaussian process-based dynamic eigenvalues as early warning signals for neuronal firing activity

Abrupt transitions in neuronal dynamics, including changes from resting to repetitive spiking, can be viewed as critical transitions in nonlinear systems. Anticipating these transitions from voltage time series is difficult because governing equations are often unavailable. Class...

IRF1-mediated thioredoxin (TXN) protects multiple myeloma cells from ferroptosis through remodeling of PUFA-containing phospholipids

Abstract Multiple myeloma (MM) is a hematologic malignancy characterized by uncontrolled plasma cell proliferation and frequent therapeutic relapse. Ferroptosis, an iron-dependent form of regulated cell death driven by lipid peroxidation, has emerged as a promising therapeutic vu...