Virginia Tech

Subtyping metabolic dysfunction-associated steatotic liver disease using electronic health record-linked genomic cohorts reveals diverse etiologies and progression

Metabolic dysfunction-associated steatotic liver disease (MASLD) is a heterogeneous condition with diverse etiologies and clinical presentations. Yet, a consensus of subtypes is lacking in MASLD. Based on latent class analysis of significant MASLD-related clinical variables, we i...

Counterfactual Behavior Cloning: Offline Imitation Learning from Imperfect Human Demonstrations

Learning from humans is challenging because people are imperfect teachers. When everyday humans show the robot a new task they want it to perform, humans inevitably make errors (e.g., inputting noisy actions) and provide suboptimal examples (e.g., overshooting the goal). Existing...

Multiobjective Risk-Based Renewal Prioritization of Water Pipeline Systems Using Genetic Algorithm

Abstract Water utilities must choose a small set of mains to renew each year under tight budgets and delivery limits, yet practice relies on heuristic rankings and ad hoc adjustments, with little evidence on how to design multiobjective, constraint-aware portfolio models. We have...

Multifunctional antagonistic mechanisms of the soybean nodule endophyte Pseudomonas sp. JDE115 against Agroathelia rolfsii

Soil-borne pathogens such as southern blight, caused by Agroathelia rolfsii , threaten soybean production and are difficult to control with chemicals. To reduce reliance on fungicides, we evaluated the soybean nodule endophyte Pseudomonas sp. JDE115 as a sustainable biocontrol ag...

ORCHA: A performance portability system for extreme heterogeneity

Heterogeneity is the prevalent trend in the rapidly evolving high-performance computing (HPC) landscape in both hardware and application software. The diversity in hardware platforms, currently comprising various accelerators and a future possibility of specializable chiplets, po...

Mono‐Material Polydisulfides for Pressure Sensitive Adhesive Tapes With Closed‐Loop Recyclability

ABSTRACT Conventional PSAs are multi‐layer materials that contain numerous additives, rendering them non‐recyclable. Efforts to develop more sustainable PSAs have predominantly focused on the adhesive layer with less attention toward the backing layer, which is typically a petrol...

Deterring Greenwashing in Travel: A Multistakeholder Action Framework

Extant research has identified positive and negative consequences of greenwashing, creating a paradox because the phenomenon is inherently deceptive and detrimental to environmental and societal well-being. This study examines these paradoxical consequences across micro-, meso-,...

System Dynamics Analysis of Construction Workforce Development

Abstract The US construction industry faces a significant workforce shortage, which is expected to increase due to the projected growth of this industry along with retirement of the current aging workforce. The workforce composition of the construction industry shows several demo...

Edible pedagogies: Designing with food, memory and emotion in the Bagel Studio

This article explores how food-making can support emotional, sensory and reflective learning in design education. Using a 15-week undergraduate and graduate industrial design studio as a case study, the project engaged 23 students in baking bagels to examine intersections of food...

Pedagogical Moves for Provoking Prospective Teachers’ Intellectual Needs while Connecting Abstract Algebra and Secondary Mathematics

Researchers have exhibited ways in which prospective secondary mathematics teachers can connect content from abstract algebra with secondary mathematics in ways that reshape their understanding of secondary mathematics and thereby support their teaching of that content. However,...

What Is the Return on Investment of Digital Engineering for Complex Systems Development Schedules? Findings From a Mixed‐Methods Case Study on the Post‐Production Design Change Processes of Navy Assets

ABSTRACT Complex engineered systems routinely face schedule and cost overruns, along with poor post‐deployment performance. Both INCOSE and the U.S. Department of Defense (DoD) have championed Digital Engineering (DE) as a potential remedy, yet most of DE's purported benefits rem...

Feeding regime alters mitochondrial metabolism in beef skeletal muscle

Abstract Plane of nutrition influences animal growth rate and muscle fiber composition, potentially through altering skeletal muscle metabolism. The objective of this study was to evaluate changes in skeletal muscle metabolism in response to altering diet without changes in growt...

Symmetric Hermite Quadrature‐Based Balanced Truncation for Learning Linear Dynamical Systems From Derivative Data

ABSTRACT Data‐driven reduced‐order modeling is an essential component in the computer‐aided design of control systems. In this work, we present a novel symmetric Hermite formulation of the quadrature‐based balanced truncation algorithm that constructs linear reduced‐order models...

Second-order AAA algorithms for structured data-driven modeling

Abstract The data-driven modeling of dynamical systems has become an essential tool for the construction of accurate computational models from real-world data. In this process, the inherent differential structures underlying the considered physical phenomena are often neglected m...

From bird viremia to bird surveillance: identifiability in a multi-scale vector-borne model of Usutu virus infection

Abstract Usutu virus is an emerging mosquito-borne flavivirus, maintained through an enzootic cycle involving wild birds and mosquitoes, with occasional spillover to humans. Understanding how interactions across these biological scales shape transmission dynamics is essential for...

Chemosymbiotic trophic strategy in an Ediacaran tubular animal

Chemosymbiosis may have been a key driver of early animal evolution and diversification. Yet evidence for animal–microbe nutritional partnerships in the fossil record of early metazoans remains scarce, largely owing to the limited availability of robust geochemical proxies and su...

Phenology-adaptive machine learning for early mapping of field-scale corn crop yield using fusion of Sentinel-2 satellite spectral imagery, and weather-based accumulated heat units

Abstract Purpose Timely, accurate, and field-scale crop yield mapping is essential for precision crop management, yet most existing studies rely on late- or full-season data, limiting in-season decision-making. This study aims to develop a stage-aware earliest possible corn yield...

Fortunate people in a fortunate land: At home in Santa Monica’s rent-controlled housing , by Lauren E. M. Everett

Few housing policies today provoke as much disagreement as rent control.1 The terms of this debate have largely been set by economists, who have long argued that these policies depress housing supp...

Torsional wake stiffness and the dynamic response of tethered tandem cylinders in the subcritical and critical regimes

This study experimentally investigates the stationary and dynamic characteristics of a tandem cylinder configuration in which the downstream cylinder is confined to rotate about a pivot point centered at a fixed upstream cylinder with a specified cylinder-to-cylinder spacing. Res...

Driving anger reduces the evasive response likelihood in near-crash events: Insights from SHRP 2 Naturalistic Driving Study

Introduction: Anger is a prevalent emotion that has been shown to negatively impact driving behavior, contributing to aggressive driving and road rage—both of which are well-known threats to traffic safety. This study investigated the effects of driving anger on evasive maneuvers...