University of Southampton

Neuromuscular electrical stimulation for pre- and post-knee replacement surgery: a qualitative study

Total knee replacement effectively relieves pain and restores function in end-stage osteoarthritis, but rehabilitation is essential to optimize outcomes. Postoperative pain, quadriceps weakness, and limited mobility can restrict participation in conventional exercises. Neuromuscu...

Volatility ≠ Risk: When Timing Alpha in Crypto Markets Reflects Mispricing

ABSTRACT Volatility timing in cryptocurrency markets generates significant alpha, but only during periods of loose monetary policy and high uncertainty. Analyzing S&P crypto indices (2017–2023) dominated by large‐cap assets, we show realized volatility can reflect noise‐driven sp...

Cyclic Peptide PROTACs Restore VHL-Mediated HIF-1α Degradation in Hypoxia

Abstract We report a systematic approach to convert cyclic peptide protein–protein interaction (PPI) inhibitors into functional degraders. We compare traditional PEG-based linkers with custom bifunctional amino acids that embed a Von Hippel-Lindau (VHL)-recruiting ligand and vari...

Thermophysiological and perceptual responses to exercise heat stress in people with cystic fibrosis on Elexacaftor/Tezacaftor/Ivacaftor

Abstract The objective of this study was to investigate thermophysiological and perceptual responses to exercise heat stress in people with cystic fibrosis (pwCF) on Elexacaftor/Tezacaftor/Ivacaftor (ETI) versus healthy controls, and to explore their lived experiences of heat str...

Deep-Learning-Assisted Single-Shot Plasma Emission Imaging for Pollen Morphology Reconstruction and Apparent Hydration-State Classification

Abstract Monitoring pollen is important for crop productivity, plant breeding, and environmental forecasting, yet current approaches remain limited in throughput and physiological insight. Here, we combine single-shot plasma emission imaging with artificial intelligence for polle...

The Impact of Sustainability Audit on Climate Change Performance: The Role of Governance Quality and Greenwashing

ABSTRACT This study investigates how sustainability audit quality influences corporate climate change performance and examines the moderating roles of governance quality and greenwashing. Using panel regressions on 6140 firm‐year observations from 39 countries between 2008 and 20...

Seamless grid following and grid forming inverter mode transition enabled by machine-learning based SCR estimation and smooth switching control

The increasing penetration of inverter-based resources has led to converter-dominated power systems in which grid strength varies significantly and strongly influences inverter control performance. Grid-following (GFL) and grid-forming (GFM) control strategies offer complementary...

Joint XMM-Newton and NuSTAR Observations of Type I X-ray Bursts from the Dipping Low-Mass X-ray Binary 4U 1323–62

Abstract In this study, we report partly simultaneous XMM-Newton and NuSTAR observations of the bursting, dipping low mass X-ray binary, 4U 1323–62 obtained in 2024. 4U 1323–62 is one of the well-known persistent bursters, with bursts occurring roughly every three hours. It is al...

Mitigating artificial intelligence-related animal welfare risks in animal farming

In animal farming, artificial intelligence (AI) is increasingly promoted as a means to enhance productivity, reduce greenhouse gas emissions, and improve animal welfare. However, discussion of the animal welfare risks arising from these technologies, particularly emerging generat...

Dielectric Permittivity Tensor of Muscovite for Next Generation All Van Der Waals Broadband Photonic Components

ABSTRACT We report a comprehensive determination of the dielectric permittivity tensor of van der Waals (vdW) muscovite, also referred to as mica, establishing it as a low‐index, low‐loss platform for next‐generation nanophotonics. Resolving its anisotropic vibrational response a...

MooBench: A micro-benchmark for performance overhead measurement of observability tools

MooBench: A micro-benchmark for performance overhead measurement of observability tools EventType Research Software Publication Abstract Understanding the runtime behavior of software is inherently difficult due to the unpredictability of the software's behavior itself and the no...

Beyond remembrance: a community-engaged framework for education for disaster justice after the Grenfell Tower Fire

Disasters expose deep-seated social inequalities and injustices, producing impacts that extend far beyond the immediate event. Although education is central to collective memory and learning from disasters, how recent tragedies might be taught meaningfully to younger generations...

Continuous-time random walk description of anomalous spin transport in dilute dipolar networks

Nuclear spin diffusion is often summarized by a single diffusion coefficient, but this coarse-grained description can fail in dilute solids where positional disorder and long-range dipolar couplings generate a broad distribution of hopping rates. We develop a continuous-time rand...

The UK RSE Community

The UK Community presentation from the RSE Worldwide Session at RSECon26, 9 September 2026.

Multiple-use prediction and calibration for all future values: Exact simultaneous tolerance bands for multiple and polynomial regressions

Multiple-use prediction and calibration for all future values play an important role in many areas, including health and medical research. Simultaneous tolerance bands (STBs) can be employed for these purposes. This article studies the construction of exact STBs for multiple regr...

Finding the thin ice before you fall through: identifying the critical software you rely on

Do you know what software you use? Do you know what software you rely on? Do you know what you would do if you couldn’t use it any more? Research Software Engineers and digital Research Technical Professionals rely on software everyday. That software relies on other software, cre...

Exogenous GA3 promotes flower bud differentiation in Lycoris aurea by modulating hormone signaling and carbohydrate metabolism

Lycoris aurea Herb. (golden spider lily) exhibits a prolonged vegetative phase and delayed flowering, limiting its ornamental and commercial value. Gibberellins, particularly GA 3 , are well-known regulators of flower bud differentiation in plants. Here, we investigated whether e...

DIALOR (DIgitAL cOaching for fRailty): a feasibility and acceptability study of a digital health coaching intervention for older people with frailty in primary care

Abstract Purpose To assess the acceptability and feasibility of a digital health platform for long-term disease management combined with health coaching for people living with mild-moderate frailty in Southwest England. Methods Older adults (65 years+) with frailty (using electro...

A year-long upper-ocean dataset from a submesoscale- and mesoscale-resolving mooring array in the Northeast Atlantic

Submesoscale processes are central to upper-ocean stratification, cross-scale energy transfers, and vertical tracer transport, yet observations that resolve their transient variability over seasonal timescales remain scarce. Here, we present a year-long record of upper-ocean obse...

A year-long upper-ocean dataset from a submesoscale- and mesoscale-resolving mooring array in the Northeast Atlantic

Submesoscale processes are central to upper-ocean stratification, cross-scale energy transfers, and vertical tracer transport, yet observations that resolve their transient variability over seasonal timescales remain scarce. Here, we present a year-long record of upper-ocean obse...