University of Sassari

Neural encoding of symbolic, non-symbolic, and embodied non-symbolic numerical information in young and older adults

Numeracy has important implications across the lifespan, and age-related decline in this ability represents a vulnerability factor for older adults in managing everyday tasks, yet its mechanisms remain poorly understood. This study employed a parity judgment task to examine age-r...

Localized brain delivery of drugs via focused ultrasound-responsive bi-layer nanobubbles

Focused ultrasound (FUS) in combination with micro- or nanobubbles is a promising strategy for transiently and non-invasively opening the blood-brain barrier (BBB) to enable targeted drug delivery to the brain. Here, we report a FUS-responsive delivery system using bi-layer nanob...

Real-World Antibiotic Strategies for Multidrug-Resistant Pseudomonas aeruginosa: Evidence from the Italian SUSANA Multicentre Study

Background/Objectives: Multidrug-resistant (MDR) Pseudomonas aeruginosa pneumonia and bloodstream infections (BSI) remain challenging because of their severity, limited therapeutic options, and high mortality, despite the availability of novel β-lactam-based agents. We aimed to d...

Mycobacterium chelonae as an Underrecognized Cause of Granulomatous Disease in Fish and Humans: A Molecular One Health Study

Non-tuberculous mycobacteria are recognized as pathogens affecting aquatic animals and humans. Although Mycobacterium marinum is traditionally considered the principal etiological agent of fish mycobacteriosis and fish-tank granuloma in humans, the contribution of Mycobacterium c...

Real‐world outcomes of venetoclax plus hypomethylating agents in unfit acute myeloid leukaemia: Results of the GIMEMA AML2320 trial

Summary Venetoclax (VEN) plus hypomethylating agents (HMAs) represents the standard of care for newly diagnosed acute myeloid leukaemia (AML) patients unfit for intensive chemotherapy, but prospective real‐world observational data outside randomized clinical trials remain limited...

Speciation,Protein Binding, Biotransformation, andCytotoxicity of a VV–Lactate Complex

Abstract We studied the speciation, protein binding, biotransformation, and cytotoxicity of the dioxidovanadium(V) lactate complex Cs2[VV2O4(lact)2]·2H2O and compared the results with those obtained for the analogous malate compound. 51V NMR and ESI-MS results show that Cs2[VV2O4...

The Circular Cultural Landscape Model: Bridging Historic Urban Landscape and Circular Economy

This article examines the conceptual and practical relationships between UNESCO’s 2011 Historic Urban Landscape (HUL) Recommendation and the European Commission’s 2020 Circular Economy (CE) Action Plan, bringing together cultural heritage conservation and sustainable resource man...

Political context and system conditions for university community engagement

The paper explores whether the political context and institutional settings of the higher education system are elements that could affect the community engagement of universities and how much it is likely to be transformative for academia. The questions guiding the research are:...

Soundscape as a proxy for seagrass meadow condition and anthropogenic activity

Soundscape analysis has emerged as a relevant tool in functional marine ecology. However, how habitat-specific variables, environmental and biological components, and external pressures influence acoustic metrics requires further validation. This study investigates how soundscape...