University of Pecs

Optimizing genotype and nitrogen management for improved yield and agronomic efficiency in dry direct seeded rice under temperate ecology

Rice production through conventional transplanting is becoming increasingly difficult because of limited water resources and labor shortages. Dry direct-seeded rice (DSR) offers a practical alternative with lower water and labor requirements. However, the success of DSR depends o...

Pelvic floor muscle function, pain, and symptom burden in women with endometriosis: a pilot case–control study

Chronic pelvic pain is one of the most disabling manifestations of endometriosis and is frequently associated with impaired quality of life, bladder dysfunction, and sexual dysfunction. Pelvic floor muscle (PFM) dysfunction may contribute to a potential contributor to symptom per...

Viral Metagenomic Analysis of Bat Fly Pupae

Bats are important reservoirs of zoonotic viruses, yet the role of their obligate ectoparasites, particularly bat flies, in viral maintenance and transmission remains poorly understood. Although viral sequences have been detected in adult bat flies, vertical transmission to their...

AI: The Illusion of Understanding

In 1980 John Searle imagined a man locked in a room with a rulebook, shuffling Chinese characters he could not read, and asked whether anything there understood anything. The thought experiment has framed the debate ever since. This paper argues that it no longer fits the machine...

Novel avian calicivirus genome with type IV internal ribosomal entry site (IRES) in black-headed gull (Chroicocephalus ridibundus) in Hungary

Abstract In this study, a taxonomically novel avian calicivirus detected and characterized by next generation sequencing, RT-PCR and Sanger sequencing methods in faecal specimen collected from black-headed gull ( Chroicocephalus ridibundus ) in Hungary. The complete genome length...

Motivational drive influences motor and cerebellar alterations in the triple transgenic Alzheimer’s disease model

Abstract Alzheimer’s disease (AD) is accompanied by early motor alterations, yet the contribution of motivational state and testing history to these changes remains poorly understood. We examined locomotor, fine-motor, and molecular profiles in 6–8-month-old male 3xTg-AD mice acr...

The Global Mode of Experience in Psychodynamic Movement and Dance Therapy - Bodily Awareness as a Therapeutic Factor: Effects and Clinical Considerations.

Bodily awareness has become a central therapeutic factor in psychodynamic and body-oriented psychotherapies, yet its clinical effects and theoretical status remain insufficiently integrated. This paper offers a clinically grounded account of bodily awareness work in Psychodynamic Mov...

From targeted SCN1A analysis to whole exome sequencing: clinical utility and novel genetic findings in a Hungarian paediatric epilepsy cohort

Abstract Epilepsy represents a highly prevalent neurological disorder with a significant genetic component, particularly implicating ion channel genes, including SCN1A . In this study, 431 individuals with heterogeneous paediatric-onset epilepsy phenotypes were assessed at the De...

Metamodernism Manifesto

Metamodernism Manifesto is a short illustrated essay that defines metamodernism through a single organising question: how much trust does an artist place in reality? Its opening claim is deliberately plain — reality has not become more complicated; we have simply begun to notice...

Cancer in systemic sclerosis: clinical associations and prognostic impact from the EUSTAR registry

BACKGROUND: Cancer represents a major cause of mortality in systemic sclerosis (SSc). Established risk factors are limited to specific subsets, particularly early diffuse anti-RNA polymerase III (POLR3)-positive disease, needing further exploration. METHODS: We performed a nested...

The effect of food price volatility on under-5 child mortality in Ethiopia

Abstract Food price volatility has posed a persistent challenge in Ethiopia for more than five decades, raising concerns about its long-term implications for child survival in the context of chronic food insecurity. Although previous studies have explored food prices and child he...

Softening the Emergency Room Experience

Emergency departments (EDs) are critical healthcare environments designed for rapid medical response; however, their spatial and sensory conditions often intensify patient anxiety and fear. While emergency architecture traditionally prioritizes efficiency, visibility, and clinica...

The clinical and molecular spectrum of AGO2-associated Lessel-Kreienkamp neurodevelopmental syndrome

Abstract Background Pathogenic variants in AGO2 ,encoding a central component of the RNA-induced silencing complex (RISC), cause the neurodevelopmental disorder Lessel-Kreienkamp syndrome (LESKRES). The variant spectrum and associated molecular mechanisms underlying phenotypic va...

P1.017. Innovative Applications of the Internal Mammary Artery in Supercharged Colon Replacement

Abstract Topic Benign Disease: Esophageal Surgery Background Esophageal reconstruction poses significant challenges, particularly when traditional methods are not viable. This study explores innovative applications of the internal mammary artery (IMA) in supercharged colon replac...

From general-purpose models to purpose-built artificial intelligence Systems for Health economic Modeling

INTRODUCTION: Health economic models (HEMs) provide a solid foundation for reimbursement policy decisions that shape patient access to new treatments and the allocation of scarce healthcare resources. Model development is labor-intensive and time-consuming, often requiring months...

Acute adaptations in dynamic torque and torque control to practicing with known and unknown sequences of concentric and eccentric muscle contractions in healthy young adults

Abstract Background During human movement, the neuromuscular system continuously adapts to varying and differently predictable demands. Practicing with sequences of known and unknown types of muscle contractions could train force control of muscle. We compared the acute effects o...

Availability and representativeness of freshwater macroinvertebrate data to enable Europe-wide assessment of biodiversity trends

Freshwater ecosystems, though covering less than 1% of Earth's surface, harbor around 10% of all species. Pressures like pollution, water extraction, and habitat loss can exhibit complex interactions in their effects on freshwater biodiversity. Understanding the effects of these...

Concurrent validity of wearable inertial sensors for postural sway assessment during quiet standing compared with force plates: a systematic review and meta-analysis

Abstract Wearable inertial sensors are increasingly used for postural sway assessment, but their concurrent validity with force plates during quiet standing has not been quantitatively synthesized. This systematic review and meta-analysis (PROSPERO: CRD42024596870) pooled concurr...

Technology-enhanced learning in nursing education: a systematic review

Abstract Background Technology-enhanced learning (TEL), including artificial intelligence (AI), virtual reality (VR), high-fidelity simulation (HFS), and gamification, is increasingly used in nursing education to address limitations in clinical training and support the developmen...

Robust LigandDocking into Challenging Hydrated BindingPockets

Abstract Correctly positioning water molecules at the drug-target interface is a major challenge in structure-based drug design. Predicting how water structure reorganizes during drug docking into the target pocket is particularly difficult. Previously, a molecular dynamics-based...