University of Parma

Adaptive low-intensity pulsed ultrasound for accelerated fracture healing and chronic tendinopathic disorders: design and controlled clinical evaluation of a portable low-cost system

Although low-intensity pulsed ultrasound (LIPUS) has been widely investigated as a non-invasive regenerative therapy, optimization of stimulation parameters for different tissue conditions and fracture severities remains an active area of research. This study presents the design...

The Behavior of the External Limiting Membrane and Ellipsoid Zone in Diabetic Macular Edema: A Population AI-Assisted Optical Coherence Tomography Study

Purpose: To investigate the behavior of the external limiting membrane (ELM) and ellipsoid zone (EZ) in diabetic macular edema (DME) using artificial intelligence (AI)-based optical coherence tomography (OCT) quantification. Methods: This was a cross-sectional study. OCT scans of...

DARE to wear: digital health promotion and disease prevention using wearable devices

Global healthcare systems are under increasing strain to ensure long-term sustainability, necessitating a transition towards proactive, preventive healthcare strategies. Wearable sensor technologies are uniquely positioned to facilitate this paradigm shift by allowing continuous...

Integrating urgent care centers into primary care networks to reduce emergency department overcrowding: a real-world implementation and evaluation

Emergency Department (ED) overcrowding is a major challenge for health systems and is often driven by high volumes of low-acuity visits. In 2023, the Emilia-Romagna Region in Italy implemented a network of community-based Urgent Care Centers (UCCs) to provide timely care for low-...

A rare case of abdominal actinomycosis mimicking ovarian cancer with presumed hepatic involvement and abdominal wall involvement

species. Because of its infiltrative growth, abscess formation, and fibrotic reaction, it may closely mimic malignant disease. We report the case of a 53-year-old woman presenting with abdominal pain and a palpable epigastric mass. Imaging showed a pelvic mass with abdominal wall...

Biomass-Waste-Derived Silica for Solvent-Lean Cu-SSZ-13 Porous Catalysts in NH3-SCR NOx Remediation

The development of biomass-waste-derived functional porous materials can support resource-conscious strategies for environmental remediation. In this study, Cu-SSZ-13 porous catalysts were prepared from rice husk ash as a biomass-derived silica source and metakaolin as the alumin...

Metabolomic insights for the authentication and traceability of antibiotic‐free pork: a pilot study

BACKGROUND: H NMR-based metabolomics approach coupled to unsupervised (principal component analysis) and supervised (orthogonal partial least squares discriminant analysis) multivariate analyses was applied to kidney (n = 47) and diaphragm (n = 54) samples of pigs from four Itali...

Special Issue: “Advancements in Actuarial Mathematics and Insurance Risk Management”

Insurance has always relied on the possibility of identifying, modelling, pricing, and managing uncertainty [...]

The power of the dish for demand-driven dietary shifts towards biodiversity restoration and sustainable food systems

Abstract Food systems drive a third of global greenhouse gas emissions, half of habitat loss and the bulk of diet-related non-communicable disease, yet sustainability agendas continue to prioritise supply-side interventions over demand-side ones. We argue that dietary shifts cons...

Lignans as a Potential Metabolomic Biomarker for Nut Consumption and EAT-Lancet Diet Score Adherence

Abstract Metabolomic biomarkers may represent reliable objective measurements and can be useful for assessing dietary intake and avoiding biases. The objective of this study is to identify novel metabolomic indicators of dietary patterns. Dietary, anthropometric, blood biomarkers...

Management of Acute Periodontal Conditions—The EFP S2k Level Clinical Practice Guideline

BACKGROUND: The European Federation of Periodontology (EFP) has developed Clinical Practice Guidelines (CPGs) for the treatment of periodontitis and for the management of peri-implant diseases. In accordance with the 2018 Classification, acute periodontal conditions are character...

Prognostic Role of Adverse Events in a Worldwide Population of Patients with Biliary Tract Cancer Treated with Chemo-Immunotherapy

Background: Biliary tract cancers (BTCs) are aggressive malignancies with limited treatment options. The addition of durvalumab or pembrolizumab to cisplatin–gemcitabine improves overall survival (OS), but validated biomarkers of benefit remain limited. Immune-mediated adverse ev...

Axisymmetric gravity currents in porous media under the Darcy–Forchheimer regime

We investigate the spreading of axisymmetric Newtonian gravity currents (GCs) propagating within an infinite, saturated porous medium bounded below by a horizontal impermeable surface. The flow is driven by buoyancy, and the intruding fluid advances due to its higher density rela...

OurMED D3.4 Guidelines for Partners Capacity Development on Mediation Techniques. Version 1.2

This Deliverable (D3.4) stems from the OurMED Summer School on Participatory Processes and Environmental Conflict Mediation in Social-Ecological Systems, co-organised with the youth-led initiative NextGen4Med and held in Oristano (Sardinia, Italy) in September 2025. The guideline...

Pacemaker Implantation in Patients With Syncope, Bundle Branch Block and Negative Electrophysiological Study

ABSTRACT Introduction The long‑term need for permanent pacemaker (PM) implantation in patients with syncope, bundle branch block (BBB), and a negative electrophysiological study (EPS) is not well defined. Methods and Results We retrospectively analyzed consecutive patients underg...

The Least Trimmed Squares for time series (LTSts): extensions for policy support applications

Abstract International organizations need to monitor large amounts of economic and financial data to prevent or uncover potential problems in policies implementation. The analysis of such time series cannot ignore the potential presence of anomalies and structural changes. In thi...

Temporal Dynamics of Clinical Response Following Fecal Microbiota Transplantation in Dogs with Chronic Enteropathy

Fecal microbiota transplantation (FMT) is a promising adjunctive treatment for dogs with chronic enteropathy (CE), but response is usually assessed at scheduled follow-up visits, potentially overlooking day-to-day fluctuations. This prospective observational study evaluated tempo...

Proportional infinite-width infinite-depth limit for deep linear neural networks

In this paper, we study the distributional properties of linear neural networks with random parameters in the context of large networks, where the number of layers diverges in proportion to the number of neurons per layer. Prior works have shown that in the infinite-width regime,...

Harnessing Silicon-Based Growing Media for Sustainable Heavy Metal Remediation in Agricultural and Urban Green Systems: A Systematic Review

Heavy metal contamination of agricultural soils and urban green spaces has become a major environmental concern, threatening ecosystem functioning, food safety, and sustainable land management. Silicon-based growing media have emerged as an environmentally friendly approach for r...

Human Macrophage Polarization Dynamics on a 3D Fibrous Polydioxanone Mesh In Vitro

The host immune response plays a central role in determining biomaterial performance, particularly through early macrophage activation dynamics at the tissue–biomaterial interface. This study evaluated the response of THP-1-derived human macrophages cultured on a fibrous extracel...