University of Parma

Dream experiences and psychological distress: a network analysis of pathological worry, depression, anxiety, and stress

Abstract Dreaming has long been implicated in emotional processing, yet the complex relationships between specific dream experiences and different dimensions of psychological distress remain insufficiently understood. This study explored the network relationships between dream-re...

The New Cardio-Oncology Frontier in Hematologic Cancers: Cardiovascular Toxicities of CAR-T Cells and Bispecific T-Cell Engagers

Chimeric antigen receptor T-cell therapy and bispecific T-cell engagers have transformed treatment of relapsed and refractory hematologic malignancies, achieving unprecedented response rates. However, their clinical adoption has revealed a complex spectrum of cardiovascular toxic...

Adult attachment, death anxiety, representation of death, and depression, anxiety, obsessive-compulsive, and somatic symptoms in early emerging adulthood: a moderated mediation model

Death anxiety has been increasingly recognized as a transdiagnostic factor associated with a wide range of internalizing symptoms, yet the psychological mechanisms linking existential concerns to psychopathology remain incompletely understood. Drawing on attachment theory and exi...

A proposed evaluation of new approach methodologies for dermal toxicity assessment of botanicals

Background Botanicals are widely used in topical formulations for cosmetics, hair care, and personal care products, reflecting consumer interest in plant-derived materials. Their complex and variable composition, presents challenges for traditional toxicological approaches develo...

Topical Ruxolitinib for Folliculitis Decalvans

The authors declare no conflicts of interest. The data that support the findings of this study are available from the corresponding author upon reasonable request.

Bimodal multiphoton catalysis via structural regeneration

Abstract Most of the current photocatalytic methodologies for the generation of reactive radical intermediates have limited redox windows and can operate within a single redox manifold. Here, to overcome these constraints, we report a purely organic photocatalyst that operates vi...

Widespread thermophilization but weak link to climate warming in Europe’s summit plant communities

Abstract Recent changes in alpine vegetation are often attributed to climate warming, particularly community composition shifts towards more warmth-associated species, or thermophilization. Here we assess the link between thermophilization and warming across 53 European mountain...

Measurement incompatibility in Bayesian multiparameter quantum estimation

We present a comprehensive and pedagogical formulation of Bayesian multiparameter quantum estimation. Within this framework, we analyse the role of measurement incompatibility and establish its quantitative effect on attainable precision. We achieve this by deriving upper bounds...

Global trends in pleural infection mortality: a WHO-mortality database analysis

Background Current data suggest that the incidence of pleural infection is rising worldwide, however mortality data on global rates, trends and variations are lacking. Objectives To estimate pleural infection mortality rates across 24 Countries from 1994 to 2020 worldwide, using...

From Geometric Complexity to Informational Dimensionality in Scaffold-Guided Tissue Regeneration

Scaffold architecture shapes tissue regeneration through the mechanical, topographical, and biochemical cues it presents to cells, yet geometrically elaborate scaffolds do not reliably produce more organized tissues, while comparatively simple architectures can exert strong organ...

Isocitrate dehydrogenase (IDH) as target for anticancer therapy in brain and gastrointestinal cancers

Isocitrate dehydrogenase (IDH) enzyme system plays a central role in cellular metabolism, growth, and differentiation, and its mutations are associated with alterations of the cell cycle and production of oncometabolites, promoting tumor development. In this narrative review, we...

Systemic Corticosteroids in Pediatric Community-Acquired Pneumonia: Evidence, Clinical Outcomes, and Phenotype-Based Therapeutic Considerations

Background: Community-acquired pneumonia (CAP) remains a leading cause of pediatric morbidity and mortality worldwide, particularly in low-resource settings. Although antimicrobial therapy is the cornerstone of treatment, disease severity is often influenced not only by pathogen...

Double functionalization in chitosan scaffolds for bone tissue engineering improvement

Abstract Chitosan is a natural polysaccharide produced by the deacetylation of chitin. It has been employed for several biomedical applications since it is biocompatible and biodegradable. In this work, two synthetic peptides were covalently grafted to chitosan to enhance cellula...

The impact of climate change on the river basins of Parma (Italy) and Kamianka (Ukraine): a comparative analysis

Abstract This study compares climate change impacts on two contrasting European river basins: the Parma River (Italy) and the Kamianka River (Ukraine) representing different ecoregions and climatic zones. The research used QGIS tools and satellite data from Landsat Collection 2 L...

Operation Melilli, forensic humanitarian medico legal activities on the largest known Mediterranean disaster: the shipwreck of April 18th, 2015

On April 18th, 2015, a boat carrying about 1,000 migrants sank in the Strait of Sicily, prompting one of the most complex recovery missions ever conducted in the Mediterranean. Operation Melilli was the first time a European Government authorized the recovery of a sunken migrant...

Regenerating bodies, shaping minds: school colonies in Italy between the First World War and the postwar years

Abstract This article examines the development and transformation of school colonies within the Italian child welfare system between the First World War and the immediate postwar period. Originally conceived as prophylactic institutions aimed at strengthening the bodies of frail...

Scanner-Measured Hand Hygiene Performance After Automated Visual Feedback-Supported Training: A Multicenter Quality Improvement Project in Italian Hospitals

Background: Healthcare-associated infections (HAIs) remain a major patient safety issue, and hand hygiene (HH) is a key preventive measure. Technologies providing immediate visual feedback may support HH training by allowing objective assessment of hand-rubbing technique. Methods...

When Pain Outruns Pathology: Toward a Bidirectional Model of Illness in Burning Mouth Syndrome

Burning Mouth Syndrome (BMS) is a chronic orofacial pain condition characterized by persistent burning sensations in the absence of consistently identifiable pathology. This mismatch between severe symptoms and inconclusive findings challenges conventional diagnostic reasoning, w...

Thermo‐Mechanical Topology Optimization: An Immersed FEM Level‐Set‐Based Approach

ABSTRACT This paper proposes a multi‐physics framework for topology optimization using an immersed level set‐finite element model. The work extends the capabilities of a recently developed immersed level‐set method to thermo‐mechanical problems, including coupling and material‐de...

Visible injury patterns in relation to reported sexual acts after sexual assault: a retrospective cohort study

Sexual assault may result in visible anogenital and extragenital injuries, but the absence of such findings remains a major challenge in forensic interpretation. This retrospective forensic outpatient study analyzed 306 adults examined after reported sexual assault at the Violenc...