University of Messina

Postpandemic Trends in Pediatric Respiratory Virus Hospitalizations: A Multicenter Study, 2019–2025

ABSTRACT Background The COVID‐19 pandemic profoundly altered the circulation of respiratory viruses in children, changing the epidemiology of acute lower respiratory tract infections. In the postpandemic period, respiratory pathogens showed marked temporal variability. The 2024–2...

Clinical, biochemical and genetic spectra of carnosinemia: a systematic review of case reports and case series

Abstract Carnosinemia, also referred to as carnosinase 1 (CNDP1) deficiency, is an ultra-rare inborn error of metabolism characterized by impaired CNDP1 activity and carnosine degradation. The clinical significance and phenotypic spectrum of this condition remain poorly defined,...

Differential Associations of Emotion Regulation Strategies and Sexual Attitudes with Sexual Shame: A Generalized Additive Model Analysis

Sexual shame is a complex, self-conscious emotion that can severely disrupt sexual and relational well-being. While emotional experiences and cognitive beliefs heavily influence human sexuality, the specific roles of emotion regulation strategies and sexual attitudes in predictin...

Two-dimensional shear wave elastography assessment of testicular stiffness in healthy cats

Two-dimensional shear wave elastography (2D-SWE) provides quantitative information on tissue stiffness over a broad field of view, but physiological values for feline testes remain poorly defined. This study aimed to characterize testicular stiffness in clinically healthy cats an...

Backward Plasma Acceleration of Aluminum, Copper, Silver, and Tantalum Ions From 10 10 up to 10 15 W/cm 2 Pulse Laser Intensity

ABSTRACT Measurements of ion acceleration in laser‐generated plasma obtained at intensities from 10 10 up to 10 15 W/cm 2 using IR laser ablation of aluminum, copper, silver, and tantalum in high vacuum are presented. At low intensity, data were acquired from the MIFT Department...

Deciphering the genomic signatures of climate vulnerability across 77 sheep breeds

Abstract Among domesticated species, sheep ( Ovis aries ) have achieved a wide geographic distribution due to their mobility, rusticity and ability to adapt to diverse environments and climatic conditions. Here, we characterise the genome-wide diversity of >1,000 sheep representi...

Qualitative and Quantitative Differences between GSR and non-GSR Source Particles Revealed by Raman Spectroscopy

Analysis of Gunshot Residue (GSR) is relevant to forensic science by providing a correlation between an individual and a firearms incident. Detection of GSR is usually made by using Scanning Electron Microscopy (SEM) coupled with energy dispersive X-ray spectroscopy (SEM-EDX). Pa...

Extracorporeal Free-Light-Chain Removal in Myeloma Cast Nephropathy: Plasma Exchange and Hemodialysis Strategies in the Era of Effective Antimyeloma Therapy

Renal impairment affects up to half of patients with newly diagnosed multiple myeloma, and roughly 2–4% require dialysis at presentation, most often because of light-chain cast nephropathy. In these patients, renal recovery is associated with the speed and magnitude of serum free...

Virologic, Lipid, Renal and Hepatic Laboratory Outcomes After Switching to Doravirine/Lamivudine/Tenofovir Disoproxil Fumarate in Treatment-Experienced People with HIV: Real-World Evidence from the SHINe-SHIC Cohort

Background/Objectives: Doravirine/lamivudine/tenofovir disoproxil fumarate (DOR/3TC/TDF) is used as a switch regimen in treatment-experienced people with HIV (PWH), particularly when simplification, lipid improvement, or avoidance of interaction-prone regimens is needed. We evalu...

Nebulized Epinephrine Versus Placebo in Infants with Moderate-to-Severe Bronchiolitis: A Randomized Controlled Trial

Background: International guidelines do not support the routine use of nebulized epinephrine for acute viral bronchiolitis. Despite its vasoconstrictive and bronchodilator properties, evidence remains inconclusive. Objectives: Day-6 fraction of inspired oxygen (FiO2) adjusted for...

Neural Interfaces for Bidirectional Sensory Restoration in Limb Prostheses: Current Evidence and Clinical Translation

Background: Restoration of sensory feedback has become one of the major goals of modern bidirectional neuroprosthetic rehabilitation, enabling the transition from conventional prosthetic replacement toward bidirectional neuroprosthetic systems capable of restoring physiological s...

An innovation-oriented multi-criteria framework for prioritizing return management strategies in e-commerce: an AHP-TOPSIS approach with VIKOR-based robustness analysis

Purpose This study investigates the main barriers affecting return management (RM) in e-commerce, where the rapid growth in product returns, further accelerated by the COVID-19 pandemic, has made reverse logistics an increasingly complex managerial challenge. The study aims to de...

Technique Analysis of Filter-Clogging Particulate Matter in Eddy Covariance Systems in a Volcanic Environment

The eddy covariance (EC) technique is a key tool in environmental monitoring, enabling continuous and non-invasive measurement of carbon dioxide (CO2) fluxes at the ecosystem–atmosphere interface. In environments characterized by high levels of airborne particulates, such as volc...

Personalized Sequential Nephron Blockade for Diuretic Resistance in Acute Decompensated Heart Failure: A Narrative Review for the Cardiorenal Clinician

Heart failure affects more than 64 million people worldwide, and admissions for acute decompensation account for a substantial proportion of cardiovascular healthcare expenditure. Achieving complete decongestion remains the principal objective of inpatient management, yet many pa...

First-Line Immune Checkpoint Inhibitors in Older Patients with Advanced Urothelial Carcinoma: A Systematic Review and Meta-Analysis

Urothelial carcinoma predominantly affects older patients, who often exhibit frailty, comorbidities, renal impairment, and reduced physiological reserve. We evaluated overall survival (OS) and progression-free survival (PFS) with first-line immune-based strategies in patients age...

Breaking the black box of SEAA: the internal drivers of authentic ESG performance

Purpose In response to calls for more critical paradigms in Social and Environmental Accounting and Accountability (SEAA), this study challenges the treatment of corporate sustainability as a “black box.” We investigate the internal mechanisms that drive authentic Environmental,...

Clinical Psychological Correlates of Malocclusion: Body Image Concerns and Oral Health-Related Quality of Life

Background: Malocclusion is a highly prevalent condition, affecting approximately 56% of the global population. Beyond its functional and physical characteristics, malocclusion has been associated with psychosocial outcomes, particularly body image concerns and perceived quality...

Data analytics and last-mile delivery in urban areas: challenges and opportunities

Purpose This research explores how data analytics can address last-mile delivery (LMD) challenges in urban areas. LMD is the most expensive, least efficient, and most environmentally damaging supply chain phase, yet analytics adoption remains uneven. Design/methodology/approach A...

Classification of Seasonal Allergic Rhinitis Patients by Prospective Patient‐Recorded Symptoms: The @ IT .2020 Project

BACKGROUND: Seasonal allergic rhinitis (SAR) has been so far classified according to frequency and severity by retrospective information based on the ARIA (Allergic Rhinitis and its Impact on Asthma) classification. Electronic symptom diaries (e-Diaries) are feasible tools to col...

Salivary hormones and adipokines are associated with glycemic control and early renal and cardiometabolic markers in children and young adults with type 1 diabetes

Abstract Purpose Type 1 diabetes (T1D) is recognized as a complex metabolic condition associated with hormonal dysregulation and early complications. This study aimed to evaluate salivary metabolic hormones and adipokines in children and young adults with T1D, and to assess their...