University of Macau

Integrated Multi‐Omics Reveals Cellular States and Microenvironmental Remodeling in Coexisting DCIS and IDC

ABSTRACT Ductal carcinoma in situ (DCIS) is a non‐invasive precursor of invasive ductal carcinoma (IDC), yet the biological mechanisms underlying the transition from DCIS to IDC remain incompletely understood. Here, we integrate spatial transcriptomics, single‐cell RNA sequencing...

Major adverse cardiac events and mortality associated with ADHD and its treatment in adults with type 2 diabetes: a multi-national cohort study

Abstract Background Attention-deficit/hyperactivity disorder (ADHD) has been linked to elevated risk of type 2 diabetes (T2D). However, the impact of ADHD and ADHD medication use on prognosis and health outcomes in T2D remains unclear. This study investigates the associations of...

Body mass index and semen quality in 11 154 men: evidence from a large-scale andrology dataset

Obesity has been increasingly linked to impaired male reproductive function, yet the association between body mass index (BMI) and semen quality remains unclear, particularly in large Asian populations. In this retrospective cross-sectional study, we analyzed 11 154 men aged 18–5...

Chronic carbonate alkalinity exposure impaired the mechanical properties of exoskeleton and the intestinal microbiota of juvenile Macrobrachium rosenbergii

Along with the global expansion of saline-alkali aquaculture, understanding the physiological adaptation of economically important species like Macrobrachium rosenbergii to alkaline stress is essential for sustainable aquaculture production. This study investigated the effects of...

Psychometric evaluation of the Chinese version of the desire to avoid pregnancy scale among emerging adults in China

BACKGROUND: Measures of fertility preference or intention, particularly those focused on fertility prevention, are increasingly needed in reproductive health, especially in countries such as China, which face challenges, such as declining fertility rates, an aging population and...

Self-organized optofluidic locking enables stable single-frequency lasing in dynamic liquid media

Liquid-state lasers are promising wavelength-agile, reconfigurable coherent light sources, but fluid gain media introduce Brownian motion, thermal transport, and refractive-index fluctuations that destabilize single-frequency emission. Here, we demonstrate that nonequilibrium flu...

Polarization-dependent nonlinear optical properties of aligned single-walled carbon nanotube arrays for actively controlled pulsed thulium-doped fiber lasers

Active control of laser operational parameters within a single fiber laser cavity remains a significant challenge due to the complex interplay between intracavity nonlinearities and loss dynamics. Here, well-aligned arrays single-walled carbon nanotubes (SWCNTs) were synthesized...

Characteristics, perceptions and challenges of popular music in mainland China’s primary and secondary music education: a systematic review

Abstract In mainland China, the Ministry of Education’s 2012 national music curriculum standards marked a growing policy emphasis on the inclusion of popular music in primary and secondary education; however, the nature and extent of its classroom implementation remain unclear. A...

An adaptive-problem structure framework for survival relevance in temporal processing

Research on survival-relevant cues and subjective time often groups stimuli into immediate-survival, reproductive, and social categories. These labels do not explain why cues within one category recruit different temporal processes across contexts and perceivers. The Adaptive-Pro...

\({\mathcal{W}}\)\({}_{\textrm{d}}\)-Convergence Rate of EM Schemes for Invariant Measures of Supercritical Stable SDEs

Abstract. By establishing the regularity estimates for nonlocal Stein/Poisson equations under [Formula: see text]-order Hölder and dissipative conditions on the coefficients, we derive the [Formula: see text][Formula: see text]-convergence rate for the Euler–Maruyama schemes appl...

Construction of LaFe0.5Ni0.5O3/g-C3N4 S-scheme heterojunction for dramatically enhanced photocarrier separation toward efficient photocatalytic deodorization of livestock wastewater: Based on in-situ irradiation XPS and fs-TAS analysis techniques

Odor emissions from livestock and poultry farms have become an urgent environmental challenge and a scientific concern. Indole is one of the predominant malodorous compounds responsible for this issue. To explore effective deodorization strategies, indole was selected as a model...

Multifunctional Roles of Magnesium Ions in Modulating Bone Regeneration-Related Cells

Magnesium ions (Mg2+) play pivotal roles in bone regeneration by regulating the biological functions of multiple bone repair-related cells. However, the effective concentration ranges and optimal concentration of Mg2+ for different cell types remain incompletely defined, which li...

An Integrated Fabric‐Pneumatic Soft Sensing System for Multi‐Site Muscle Activity Decoding

Force myography (FMG) decodes movement intent from muscle deformation rather than bioelectrical signals, avoiding electrode–skin coupling issues that constrain surface electromyography. Most FMG implementations rely on rigid force‐sensitive resistors with limited conformability....

Electrical feedthrough governs symmetry of phononic frequency combs in MEMS resonators

Understanding parasitic electrical feedthrough in microelectromechanical (MEMS) resonators is essential for controlling nonlinear spectral phenomena. Here, we demonstrate that electrical feedthrough fundamentally governs the symmetry of phononic frequency combs in a capacitively...

The social presence of artificial intelligence in the MICE industry: Conceptualization, scale development, and validation

Artificial intelligence is rapidly reshaping the meeting, incentives, conferences and events industry which forms part of the broader tourism industry. Social presence is a central construct in human-artificial intelligence interaction research, yet its conceptualization and meas...

Event-triggered neural network adaptive hybrid attitude control

In this paper, we develop an adaptive controller for rigid-body attitude tracking systems that combines a neural network architecture with an event-triggered mechanism. We design a quaternion-based nonlinear controller that employs a neural network to compensate for state-based d...

Can AI replace the stars? The effectiveness of celebrity avatars in emotional connections

Purpose This research aims to investigate how consumers respond to celebrity avatars compared to human celebrities in relational communication contexts. It examines whether parasocial bonds formed with real celebrities transfer to their AI-powered avatar representations. Specific...

Perioperative non-invasive neuromodulation for delirium and cognitive recovery: from preclinical evidence to clinical translation

Perioperative neurocognitive disorders (PND) are a challenge for patients to accelerate postoperative recovery, and exploring more effective interventions can help reduce long-term cognitive dysfunction. Non-invasive neuromodulation (NIN) has shown potential in improving postoper...

A Homozygous Variant in DMRTB1 Is Associated With Non‐Obstructive Azoospermia in Humans

ABSTRACT Non‐obstructive azoospermia (NOA) represents the most severe form of male infertility, and the pathogenesis in partial patients can be attributed to endocrine dysfunction or heritable genetic variants. Although the application of whole‐exome sequencing (WES) has facilita...

Probabilistic transient stability assessment of power systems with renewable energy using a bounded-Transformer embedding fault severity rules

The increasing penetration of renewable energy introduces significant uncertainty into modern power systems, posing an unpredictable challenge to their stable operation. However, conventional transient stability assessment methods only provide a deterministic result, ignoring the...