University of Luxembourg

Causal analysis of Alzheimer’s disease molecular data

Abstract Background Genome-wide studies have revealed many molecular associations with Alzheimer’s disease (AD), but association alone does not identify cause, mechanism, or treatable target. This review surveys methods used to infer causal relationships from AD molecular data an...

Convivialism discovers the subject: A mostly appreciative commentary on the Third Convivialist Manifesto

The Third Convivialist Manifesto marks a shift: while its two predecessors located the displacement of conviviality in a material-economic logic, its current iteration relocates it in a psycho-political one. It foregrounds ‘the subjective’ – diversity, identity, and the struggle...

Physics vs. AI in weather prediction: evaluating GraphCast, AIFS, and FuXi against an observation-corrected WRF model for flash floods

Abstract. Data-driven artificial intelligence (AI) weather models are increasingly positioned as alternatives or complements to physics-based numerical weather prediction (NWP) systems, yet systematic model evaluation studies that compare both paradigms under controlled experimen...

Evaluating OpenMP Offloading for Intra-Node Multi-GPU Programming Across NVIDIA, AMD, and Intel Architectures: A 3D Heat Transfer Case Study

Currently, many of the leading supercomputers are equipped with GPUs from manufacturers such as NVIDIA, AMD, or Intel, which provide substantial parallelism and high throughput. It is common for a single compute node to host multiple GPUs (typically four or more); we refer to thi...

Disease Duration Differentiates Freezing of Gait Response to Subthalamic and Nigral Stimulation for Parkinson's Disease in an Exploratory Multicenter Controlled Trial

BACKGROUND: Freezing of gait (FoG) belongs to most pressing unmet symptoms in the treatment of Parkinson's disease. OBJECTIVES: To explore whether combined subthalamic and nigral (STN + SNr) deep brain stimulation improves FoG compared with optimized STN stimulation alone; to ide...

Neoliberal policies as catalysts of inequality after disasters: Mapping (Im)mobilities and the effects of floods in Porto Alegre, Brazil

The 2024 floods in Porto Alegre, Brazil, suggest how urban planning shaped by neoliberal reforms may intensify vulnerability during climate disasters. Using spatial analysis, policy review, and a survey of 417 residents across five neighborhoods, this study finds that the privati...

Driving sustainability, resilience, and digitalisation in automotive supply chains: A stochastic maturity model for future-oriented transformation

Digitalisation, resilience, and sustainability are key drivers of contemporary supply chain transformation, requiring organisations to make strategic decisions under conditions of uncertainty. To support such decisions, this paper presents a stochastic maturity model that support...

Freely adding one layer of quantifiers to a Boolean doctrine

We describe the layer of quantifier alternation depth at most one of the quantifier completion of a Boolean doctrine over a small category. This amounts to a doctrinal version of Herbrand's theorem for formulas with quantifier alternation depth at most one modulo a universal theo...

Complementary Eigen–Zundel Interpretation Reconciles Thermodynamics and Spectroscopy of Excess Protons in Aqueous HF Solutions

ABSTRACT Aqueous solutions of HF and HCl behave very differently at intermediate concentrations: HCl dissociates completely, whereas HFonly partially dissociates and forms bifluoride (). This should lead to markedly different excess‐proton spectra in HF and HCl solutions, in cont...

Two protons, two positrons, and four electrons: Covalent bond with van der Waals characteristics

Classifying interactions is key in the physical sciences, and bonding mechanisms in matter-antimatter systems remain particularly enigmatic. Here, we focus on a paradigmatic example of positronium hydride (PsH) dimer composed of two protons, two positrons, and four electrons, who...

When German Soldiers Became Belgian Veterans: A Cross-Border Mixed Economy of Veteran Welfare After the First World War

When the regions of Eupen, Sankt Vith and Malmedy switched from German to Belgian state sovereignty in the aftermath of the First World War, the local inhabitants who had served in the German army had welfare needs, demands or aspirations that could no longer be legitimated by me...

Cost learning and strategic inventory: who should carry inventory in a vertical supply chain?

Problem Definition: In a decentralized supply chain, the downstream retailer (he) may strategically carry inventory to induce lower future wholesale prices, triggering the upstream manufacturer (she) to raise the early-period wholesale price to deter such behavior. In the presenc...

The two square root laws of market impact and the role of sophisticated market participants

The goal of this paper is to disentangle the roles of volume and of participation rate in the price response of the market to a sequence of transactions. To do so, we are inspired the methodology introduced in (Quant. Finance 15 (2015) 1123–1135; Math. Finance 30 (2020) 1309–1336...

Between Sex and Work: Regulating Webcamming Under the Platform Work Directive

Abstract This article examines the European Union Platform Work Directive (PWD) through the lens of webcamming, a form of platformised sex work largely excluded from regulatory debates on platform labour. Drawing on legal analysis and empirical research with webcam performers and...

LangBiTe: model-driven bias testing of text-to-text large language models

Large language models (LLMs) have rapidly gained popularity across a wide range of applications, from customer support to content generation and decision support systems. However, LLMs have also been found to exhibit social biases, reflecting and amplifying stereotypes and prejud...

The same model, different responsibilities: Responsible NLP under the EU AI Act

Abstract The European Union’s Artificial Intelligence Act changes the governance environment in which natural language processing (NLP) systems are developed and deployed. Its central lesson for Responsible NLP is that responsibility does not follow automatically from a model’s a...

Curriculum development in midwifery education: a systematic literature review

Midwifery has undergone a significant transformation in recent decades, evolving from vocational training to university-based education. Despite international recommendations supporting competency-based education and professional regulation, little is known about how midwifery cu...

Awareness of age-related changes and happiness in daily life: Moderating effects of perceived control.

= 7.76). On the between-person level, age-related losses were related to lower levels of happiness only for individuals who reported low perceived control. On the within-person level, days with more losses or fewer gains were days with lower happiness, and these relations were mo...

Activities and Role Perceptions of Clinical Research Nurses in Participating Italian Scientific Research Hospitals: A Multicentre Cross-Sectional Survey

Background/Objective: Clinical research nurses (CRNs) support participant care and trial conduct, yet their role is inconsistently recognised and integrated in Italian Scientific Institutes for Research, Hospitalisation and Healthcare (IRCCSs). This study aimed to describe the pe...

What if it was not about human extinction at all, but a glitch inside the frontier lab matrix?

This Perspective asks whether some of the most unsettling recent developments in frontier artificial intelligence may point to a different class of risk than the familiar narrative of human extinction. Drawing on recent agentic security incidents, research on reward hacking and e...