University of Kansas Medical Center

Pediatric Mental Health Screening Practices Across Health Systems: A Multistate Survey

Despite an ongoing youth mental health crisis, mental health screening practices by pediatric health systems are unknown. The aim of the current study is to describe mental health screening practices in pediatric health systems and identify potential targets for improvement. Pedi...

Exploration of the genetic architecture of ANCA-associated vasculitis

Background Antineutrophil cytoplasmic antibody-associated vasculitis (AAV) is a complex autoimmune disease with distinct clinical and serological subtypes. Previous genome-wide association studies (GWAS) have identified several susceptibility loci, particularly within the major h...

Impact of resistance training on mobility among obese individuals living in the US

Date presented: April 23, 2026 Primary Author and Speaker: Thomas Rosenblum, thomas.rosenblum@spartans.ut.edu

Clinical Outcomes and Hospital Resource Utilization Among Patients with Sepsis and COVID-19 Infection: Insights from the United States National Inpatient Sample Analysis, 2020–2022

Background/Objectives: Clinical studies have shown that patients who had sepsis with COVID-19 infection had worse clinical outcomes; however, there is a paucity of data on the association between concurrent COVID-19 infection and outcomes among patients with sepsis. Hence, we con...

Health Inequalities, Intersectionality, and Justice

Policy Points Population health science that uses large data sets to study health inequalities increasingly draws on intersectionality, the idea that overlapping forms of disadvantage shape health inequalities. This approach is essential to the pursuit of health equity because it...

Autism Severity, Behavioral Interventions, and ADL Difficulties in Children 6–17 Years

Date presented: April 24, 2026 Primary Author and Speaker: Cara E. Nightlinger, nightlinger147@gmail.com

Medicaid utilization in children: Condition‐specific incidence and spending

Abstract Medicaid insures over half of US children, yet gaps remain in understanding how funds are allocated across the care of nonchronic conditions, the care of chronic conditions, and preventative services. We conducted a retrospective analysis of 7.2 million Medicaid‐enrolled...

High-resolution binding data of TFIID and cofactors show promoter-specific differences

Abstract TFIID is instrumental in recognizing promoter sequences and initiating transcription, yet a cohesive understanding of how this complex engages and functions at different promoter types in vivo is still lacking. Here, we employed ChIP-nexus to capture high-resolution bind...

Claudin-2 protects from enteropathogenic E. coli-infection and colitis by promoting crypt fetalization via β1-integrin/FAK/YAP signaling

Abstract Citrobacter rodentium ( Cra ) infection, a murine model of enteropathogenic Escherichia coli (EPEC) infection, induces crypt proliferation that potentially promotes mucosal healing and pathogen clearance, yet the underlying molecular mechanisms remain poorly understood....

Prognostic implications of complications during VA-ECMO for cardiogenic shock

PURPOSE: Veno-arterial extracorporeal oxygenation (VA-ECMO) provides comprehensive cardiopulmonary support in patients with cardiogenic shock (CS), but may result in complications. While complications rates are known, their impact on risk of death remains largely unknown. METHODS...

Metabolic and neural responses to ultraprocessed foods: a randomized, controlled, crossover study

Dietary patterns worldwide have shifted toward increased consumption of ultraprocessed foods (UPFs), which has been linked to higher disease burden. One proposed mechanism underlying both UPF consumption and metabolic disease is altered post-ingestive responses relative to nutrit...

Low dose methotrexate enhances lymphocytic JAM-A expression in rheumatoid arthritis

Objectives Endothelial Junction Adhesion Molecule A (JAM-A) functionally manages immune cell infiltration via tight junctions during the pathological development of human immune diseases. However, the expression and function of JAM-A on peripheral lymphocytes are yet to be well u...

When Caregivers Disagree: Clinical Decision Making in High-Conflict Custody Arrangements

High-conflict custody arrangements introduce additional complexity into child psychiatric care, particularly in the domains of consent, communication, and continuity of treatment. In these settings, clinical decision-making must extend beyond diagnosis and pharmacological managem...

Timing and trajectory of acute kidney injury predict mortality in alcohol-associated hepatitis: A multinational cohort study.

BACKGROUND: Acute kidney injury (AKI) is common in alcohol-associated hepatitis (AH) and associated with poor outcomes, yet the prognostic implications of AKI timing and early renal trajectory remain unclear. METHODS: In this prospective multicenter cohort from the Global AlcHep...

Ferroptosis in liver biology and diseases.

Ferroptosis is a form of non-apoptotic cell death driven by iron-dependent lipid peroxidation (LPO). Ferroptosis is closely associated with hepatic metabolic pathways, particularly those involving iron, fatty acids, amino acids, and redox changes. This review aims to provide a co...

A Systematic Review and Meta-Analysis of the Prevention and Management of Pediatric Urinary Tract Infection and Suspected Urinary Tract Infection: Technical Report

BACKGROUND AND OBJECTIVE: Urinary tract infection (UTI) is a common bacterial infection during childhood. This article reports on a technical review investigating the management of UTI to inform the development of an updated clinical practice guideline (CPG) by the American Acade...

Clinical Practice Guideline for the Diagnosis and Treatment of Urinary Tract Infection in Children From 8 Days to 5 Years of Age

Urinary tract infection (UTI) is one of the most common bacterial infections in infants and young children, with a prevalence of 7% in infants with fever. This clinical practice guideline (CPG) provides an update of the literature and clinical recommendations of the 2011 American...

Urinary Tract Infection Diagnosis—A Companion to the American Academy of Pediatrics’ 2026 Clinical Practice Guideline on the Diagnosis and Management of Urinary Tract Infection: Technical Report

Accurate diagnosis is essential to appropriate care. Although urinary tract infection (UTI) is one of the most common bacterial infections in children, there is no gold standard for its diagnosis. During the American Academy of Pediatrics' revision of its Clinical Practice Guidel...

A Systematic Review and Meta-Analysis of the Role of Ultrasonography for the Diagnosis of Vesicoureteral Reflux in Pediatric Patients Following Urinary Tract Infections: Technical Report

BACKGROUND: Vesicoureteral reflux (VUR) may be present in as many as 40% of children without known underlying neurogenic bladder or anatomic abnormalities in whom a first urinary tract infection (UTI) is diagnosed. This article reports on a technical review investigating the diag...

Financial Toxicity and Quality of Life After Bone Marrow Transplant: A Longitudinal, Prospective Study

PURPOSE Financial toxicity is common after bone marrow transplant (BMT) and is associated with worse quality of life, but longitudinal patterns remain poorly understood. METHODS We conducted a prospective cohort study of insured adults undergoing allogeneic BMT (2018-2023). Finan...