University of Gdańsk

The representation of order and randomness in the auditory cortex

Perception fundamentally relies on the brain’s ability to extract structure from its sensory environment. The auditory cortex possesses significant sensitivity to statistical regularities in tone sequences. To examine this phenomenon at the single-neuron level, we used multitone...

Integrating Drug Physicochemistry and Hfq-Dependent Regulation of Ciprofloxacin Accumulation in Escherichia coli

Ciprofloxacin (CIP), an amphoteric fluoroquinolone, undergoes pH-dependent changes in protonation state that influence membrane permeability and intracellular accumulation. Here, we investigated how drug physicochemistry and bacterial regulatory pathways jointly determine CIP acc...

DAPEG, a Modular Peptidomimetic Concept for Intracellular Delivery: Architecture, Trajectory, and Outlook in the Context of Peptidomimetic Transfection Reagents

Abstract Cell-penetrating peptides (CPPs) remain a leading nonviral strategy for the intracellular delivery of polynucleotides and folded proteins, but native α-peptide CPPs are constrained by proteolysis, dose-dependent cytotoxicity, and endosomal entrapment. Peptidomimetic rede...

Unveiling the Identity of Unio crassus (Bivalvia: Unionidae) in Central and Eastern Europe

Background/Objectives: Freshwater mussels (Bivalvia: Unionida) are among the most endangered faunal groups. This study examines the genetic diversity of Unio crassus, a species critically endangered in Europe. Methods: Using novel (nadh3-tRNA-nadh2) and existing (cox1) mitochondr...

Why don't all birds lay early? Causes and consequences of breeding timing for a long‐lived migratory seabird

The relationship between earlier laying and higher breeding success is well-established in avian species. However, a wide distribution of breeding timings is often maintained within a population, and the causes and consequences of this variation require further exploration, parti...

Overland corridors as a substitute for ocean freight in China–Europe trade

Overland corridors offer alternatives to ocean freight, but rising railway traffic does not by itself demonstrate maritime substitution. This study evaluates the scale, direction, and commodity composition of reported modal reallocation in China–European Union trade. An original...

Urban Ecosystem Services for Climate-Resilient Landscapes: Evidence, Trade-Offs, and Multifunctionality in Green Spaces, Urban Forests, and Blue–Green Infrastructure

Cities worldwide face mounting resilience challenges as climatic threats intersect with rapid urbanisation, declining ecosystem services and biodiversity, growing socioeconomic inequality, reduced human–nature integration, and environmental issues such as soil sealing, pollution,...

The AML-Associated A338V Mutation Rewires GPR183 Signaling through C-Terminal Ensemble Redistribution

Abstract G protein–coupled receptors (GPCRs) rely on dynamic conformational ensembles to coordinate G protein activation and recruitment of regulatory transducers such as GPCR kinases and β-arrestins. The oxysterol receptor GPR183 has been implicated in hematological malignancies...

Genome-wide synthetic lethality screen of Bam complex-associated genes in Escherichia coli

Abstract Biogenesis of the bacterial outer membrane is key to bacterial survival and antibiotic resistance. Central to this is the β-barrel assembly machine (Bam) complex and its associated chaperones, which are responsible for transport, folding and insertion of outer membrane p...

Towards local and compositional measurements in quantum field theory

A universal framework for the joint measurement of multiple localized observables in quantum field theory satisfying spacetime locality and compositionality is still lacking. We present an approach to the problem that is based on the one hand on the positive formalism, an axiomat...

Ultrasound-Induced Mechanoluminescence: From Remote Activation to Emerging Photonic and Biomedical Applications

Abstract Mechanoluminescence (ML) has traditionally been understood as a mechanically induced light emission phenomenon activated by direct contact stimuli such as fracture, deformation, or friction. The emergence of ultrasound (US) as a remote, noncontact mechanical excitation s...

Mitochondrial transcript abundance in breast cancer circulating tumour cells may reflect both blood-derived transcripts and biological heterogeneity

Circulating tumour cells (CTCs) are rare cells frequently profiled on a single cell level. A key indicator of single-cell transcriptome quality is the percentage of reads encoded by genes in the mitochondrial genome (MT-reads). No systematic data exists on MT-reads content in CTC...

Counterion Structure Tunes Cetyltrimethylammonium Association in Water: Thermodynamics and Weak-Contact Networks

Abstract The role of counterion structure in the stability and interaction mechanisms of cetyltrimethylammonium ion pairs was investigated by employing isothermal titration calorimetry (ITC), molecular dynamics simulations, and quantum-chemical calculations. Alkyl sulfate anions...

Self-Consistent Diagrammatic Theory of Energy Migration and Trapping on Spherical Nanoparticles

Abstract We present, for the first time, a comprehensive theoretical model that elucidates multistep energy migration, including its remigration in the donor ensemble, followed by nonradiative excitation transfer to acceptors, on a finite-radius spherical nanoparticle labeled wit...

Time symmetry in quantum theories and beyond

There exists a stark tension among different formulations of quantum theory as some are inherently time-symmetric while others are time-asymmetric. This tension is crisply captured when considering physical theories as theories of processes. We present the process theory of quant...

Chirality enhances diffusion in disordered environments

Chirality, a systematic rotational bias in the motion of a particle, arises in a wide range of physical and biological systems, from charged colloids in magnetic fields to swimming bacteria near surfaces. While its effects in homogeneous environments are well understood, the inte...

Poland's state capitalism, state dirigisme and the European Games

This article examines Poland's organisation of the 2023 European Games as a case study of state capitalism and dirigisme under the Law and Justice (PiS) government. Drawing on qualitative analysis of official documents, public statements and media coverage, the study examines the...

The new settlement landscape of Kuyavia in the second half of the 5th millennium BCE: Longhouses as emblems of identity, drivers of agglomeration, and components of central settlements

Around 4350 BCE, the region of Kuyavia witnessed profound social and cultural transformations that led to the emergence of the Brześć Kujawski culture (hereafter BKC). The principal marker of this new identity, as well as a fundamental component of a complex settlement system, wa...

Environmental versus endogenous drivers of body condition in the Mute Swan (Cygnus olor): a comparison of coastal and inland wintering populations

Body condition reflects energy acquisition and is a key trait in studies of animal behaviour, ecology, and conservation. We examined age-, sex-, and region-related variation in the body condition of Mute Swans ( Cygnus olor ) wintering in coastal and inland regions differing in m...

Automorphisms of the Pants Graph of a Nonorientable Surface

We prove that, except in certain low-complexity cases, the automorphism group of the graph of pants decompositions of a nonorientable surface is isomorphic to the mapping class group of that surface.