University of Gdańsk

Long-Term Sequelae in Patients Treated for Recurrent CNS Relapses of Pediatric B-Cell Acute Lymphoblastic Leukemia: 20-Year Follow-Up, Neurological Consequences, and Survivorship Burden—A Case Report and Literature Review

Central nervous system (CNS) relapse remains a major cause of treatment failure in pediatric acute lymphoblastic leukemia (ALL). Repeated isolated CNS relapse is particularly rare and associated with poor prognosis, while optimal therapeutic strategies remain insufficiently defin...

Agile-mindset leadership as agile-cultural practice. Leaders’ and followers’ views per gender

Purpose This study aims to examine whether the agile-mindset leadership paradox, characterized by the inevitable tension between agile staff (minority) and non-agile staff (majority), can be catalyzed by an agile culture and how leaders and followers perceive the efficacy of this...

Anatomy, histology, and histochemistry of the harderian and lacrimal glands in the great spotted woodpecker (dendrocopos major)

Abstract The Harderian and lacrimal glands are the main orbital glands of the avian lacrimal apparatus and contribute to the tear film, nictitating membrane function, and local protection of the ocular surface. Although the ocular adnexa have been well described in domestic birds...

Efficacy and safety of seawater-based nasal irrigation on nasal congestion in infants and toddlers with common cold: a randomized controlled trial

Abstract Background Nasal congestion associated with the common cold is a frequent source of distress in infants and toddlers. While hypertonic seawater solutions offer a physiological mechanism for decongestion via osmosis, robust clinical evidence supporting their use as an adj...

Development of Functional Synbiotic-Designed Sorbets as Carriers of Lactiplantibacillus plantarum 299v and Fruit-Derived Bioactive Compounds: Probiotic Survival, Physicochemical Quality, Consumer Acceptance, and Purchase Intention

The growing demand for dairy-free functional foods has created a need for fruit-based products that simultaneously provide probiotics, prebiotics, and bioactive compounds. This study evaluated seven high-fruit synbiotic-designed sorbets prepared with raspberries, strawberries, ha...

When agile and non-agile mindsets collide: mastering paradox management to navigate the VUCA

Purpose Today’s volatile, uncertain, complex, and ambiguous (VUCA) world is driven by technology, agile leaders, and their diverse teams comprising employees with both agile and non-agile mindsets. Since the VUCA environment is full of paradoxes, the question arises: How does the...

Health as a Decision Problem in BioCognitive Architectural Design: A Critical Review and Physiological–Regulatory Perspective

BioCognitive Architectural Design (BCAD) positions architecture as an active modulator of human biological and cognitive processes, yet the operational status of health within architectural decision-making remains unclear. Although evidence linking built-environment conditions to...

Integrated in silico and experimental analysis of a stress-responsive DOXC21-A natural antisense transcript suggests small RNA-associated regulation in Arabidopsis thaliana

Abstract Background Natural antisense transcripts (NATs) represent an important regulatory layer that can modulate gene expression in plants. However, their functional relevance at specific stress-responsive loci and evolutionary emergence remain poorly characterized. The DOXC21...

Very-long chain fatty acids increase cell membrane thickness and impair mitochondrial function of aortic smooth muscle cells: implications for early vascular ageing

Aleksandra Hliwa-Ślazyk, Magdalena Narajczyk, Magdalena Dzitkowska-Zabielska, Marika Franczak, Tomasz Sledzinski, Krzysztof Narkiewicz, Adriana Mika; Very-

Temporal Histological Tissue Responses Following Fractional Non-Ablative 1470 nm Laser Exposure: A Pilot In Vivo Human Study

Abstract Background Fractional non-ablative lasers enable controlled dermal heating while preserving epidermal integrity. The 1470 nm wavelength shows strong water absorption and moderate penetration, but in vivo human histological data on early tissue responses remain limited. O...

Ordinal patterns with ties and tolerance provide a physiology-driven method to quantify cardiorespiratory interactions

We propose a new analytical approach based on ordinal pattern analysis to investigate respiratory heart rate variability (RespHRV, also called respiratory sinus arrhythmia), specifically modulation of heart rate across different phases of the respiratory cycle. The method uses RR...

Biomimetic Chromatography Profiling of a Neurotoxicology-Relevant Compound Panel: A Physicochemical Dataset for New Approach Methodologies

Developmental and adult neurotoxicity are hard to assess with conventional in vitro assays, which rarely account for how a chemical actually distributes once inside the body. Biomimetic chromatography offers a practical way to fill that gap, using stationary phases that mimic pho...

MSP4BIO Deliverable 3.4: Ecological toolkit (ESE1) for MPAs prioritization and networking

The Ecological Toolkit (ESE1) was developed to support the design, establishment and management of Marine Protected Areas (MPAs) by improving decision-making processes, focusing on prioritisation of areas, integration of connectivity processes and assessment of human impacts on m...

MSP4BIO Deliverable 3.4: Ecological toolkit (ESE1) for MPAs prioritization and networking

The Ecological Toolkit (ESE1) was developed to support the design, establishment and management of Marine Protected Areas (MPAs) by improving decision-making processes, focusing on prioritisation of areas, integration of connectivity processes and assessment of human impacts on m...

Unique geochemical conditions and microbial composition of pockmark sediments in a brackish-water eutrophic continental shelf sea

Abstract In marine pockmarks, interactions between outflowing gas, infiltrating freshwater, and increased input of organic matter (OM) affect the supply and utilization of particular electron acceptors required primarily for OM mineralization. Consequently, geochemical processes...

Cellular automata can really solve the parity problem

Abstract Determining properties of an arbitrary binary sequence is a challenging task if only local processing is allowed. Among these properties, the determination of the parity of 1s by distributed consensus has been a recurring endeavour in the context of automata networks. In...

Energy Crop Cultivation of Miscanthus × giganteus on Biochar‐Amended Marginal Soils With Conventional and Waste‐Derived Fertilization: Biomass Allocation and Nutrient Dynamics Toward Closing Nutrient Loops

ABSTRACT Sustainable production of lignocellulosic biomass on marginal lands requires strategies that enhance yield while minimizing nutrient losses and supporting circular resource use. In this study, a two‐year (2023–2024) greenhouse meso‐scale experiment was conducted using Mi...

N-terminal acetylation modulates peptide stability, fibrillogenesis and MMP-7 processing

Abstract Short self-assembling peptides are versatile building blocks for enzyme-responsive nanostructured biomaterials. Here, we investigate how N -terminal acetylation affects the stability, fibrillogenesis, and protease-mediated fragment formation of two modular peptides, ug51...

Whole-Genome Sequencing Identifies Potentially Causative Variants in SOX30, AKAP4, and RNF220 in Non-Obstructive Azoospermia

More than 70% of non-obstructive azoospermia (NOA) cases remain idiopathic, and the underlying genetic causes need to be investigated. In this study, we aimed to identify genes and variants associated with the etiology of NOA. Two NOA patients from consanguineous families, with n...

Day length may impose an ecological constraint on chick provisioning behaviour in a high-latitude seabird

Abstract Variation in daylight hours may shape light-dependent behaviours both across seasons and among latitudinally distinct breeding colonies. We investigated the influence of photoperiod variation on chick provisioning behaviour in a high-latitude seabird, the Manx shearwater...