University of Florida

Sorbitol dehydrogenase aids grain-fill and integrates carbohydrate metabolism with redox in the hypoxic maize endosperm

Abstract Extreme low oxygen is typical of microenvironments inside developing grains, thus requiring metabolic adaptations to hypoxia. Potential contributions from sorbitol dehydrogenase (SDH) are tested here for maize (Zea mays) since the reversible reaction (fructose + NADH ↔ s...

Neurodegeneration and inflammation in a novel spinocerebellar ataxia 13 preclinical model

Abstract Neuroinflammation is a critical pathological feature underlying neurodegenerative diseases. Spinocerebellar ataxia 13 (SCA13) is a heterogeneous ataxia with several allelic variations of differing phenotypes. All are neurodegenerative and currently without effective trea...

Inefficacy of essential oil-based products used as residuals for German cockroach (Blattella germanica L.) control

German cockroaches, Blattella germanica (L.) (Blattodea: Ectobiidae), remain one of the most challenging indoor pests to manage. Current pest management practices rely heavily on synthetic insecticides, but insecticide resistance has rendered many of these products ineffective. F...

Why Colonoware? Exploring Functional Variations in Hand-Built Coarse Earthenwares across the Historical Upper Southeast

Abstract Colonoware, a hand-built, low-fired coarse earthenware, appears on archaeological sites occupied from the mid-seventeenth to the mid-nineteenth century throughout the southeastern United States. Although colonoware is highly variable in appearance and abundance, it is ev...

Gross Agricultural Emissions and Unequal Mitigation Pathways in the Brazilian Legal Amazon: Implications for Climate Justice and the Sustainable Development Goals

ABSTRACT Climate mitigation policies in the Brazilian Legal Amazon have largely focused on aggregate or net emissions, providing limited evidence on how gross agricultural emissions reveal the intensity of productive emission sources independently of carbon removals. This gap con...

Identifying the state dependent drivers associated with Florida red tide (Karenia brevis) initiation, proliferation, and termination

Harmful algal bloom (HAB) initiation, proliferation, and termination occur across highly variable spatial and temporal scales, complicating efforts to link bloom dynamics to environmental drivers. This study presents a novel approach to identify state-dependent factors associated...

Coupling Soil Testing Data with Machine Learning Algorithms to Predict Plant Responses to Phosphorus in Sub-Saharan Africa

Abstract Optimizing phosphorus (P) management in agriculture is critical for food security and sustainable development. In this study, using maize as a model crop, we propose and validate a machine learning–based framework that integrates soil testing data, management practices,...

Nitrous oxide emission from croplands: biogeochemical drivers, nitrification inhibitors, policy implications, and future directions

Abstract Nitrous oxide (N 2 O) emissions from croplands are a distinct environmental challenge because N 2 O is both a potent greenhouse gas and a major contributor to stratospheric ozone depletion. Emissions arise largely from agricultural nitrogen (N) inputs and microbially med...

Agriscience teachers’ perceptions of integrating science within plant science curricula after an immersive professional development program

Abstract Secondary education focused on building students' science, technology, engineering, and mathematics (STEM) literacy is crucial for maintaining the United States' innovation workforce. However, few studies have examined how immersive, content‐specific professional develop...

Large‐scale nuclear and plastid phylogenomic analyses inform an updated Angiosperm Phylogeny Group classification: APG V

Abstract We present here a revision of the APG classification that considers the extensive recent analyses of hundreds of nuclear and plastid genes for many angiosperm species. Although previous versions of the APG classification were largely based on uniparentally inherited mark...

A yeast model for the functional analysis of SRP54 mutations associated with severe congenital neutropenia

Mutations in the human SRP54 gene are linked to the pathophysiology of severe congenital neutropenia (SCN). SRP54 is a key protein comprising one of the six protein subunits of the signal recognition particle responsible for cotranslational targeting of proteins to the ER. Crysta...

Structural Control of Phthalate Toxicity in Agricultural Soil Biofilms: Aliphatic-Chain-Length-Driven Hazards Revealed by Field Evidence, Multiomics, and Quantum Chemical Analysis

Abstract Phthalates (PAEs) pose significant ecological risks in greenhouse soils because of their hydrophobicity and persistence. This study combined field survey, microcosm experiments, multiomics analysis profiling, and quantum chemical calculations to investigate how the aliph...

Identifying and characterizing eating disorder discourse on Chinese social media: a machine learning approach

Eating disorders (EDs) are severe psychiatric conditions with high mortality and substantial medical complications. In China, underdiagnosis and low treatment engagement hinder timely intervention. Social media platforms provide a naturalistic lens into ED-related experiences, ye...

Molecular Detection and Phylogenetic Characterization of CPV-2c in Apparently Healthy Domestic Cats in the Guadalajara Metropolitan Area, Mexico

Carnivore protoparvovirus 1 variants (CPV-2a, CPV-2b, CPV-2c) have progressively expanded their host range to domestic cats (Felis catus), causing subclinical infection or panleukopenia-like disease. CPV-2c dominates among dogs in Western Mexico, but its presence in the local fel...

KRstereo: Predicting β-Hydroxy Stereochemistry in Polyketides Using Protein Language Models

Abstract Polyketides are a major class of bioactive natural products whose activities are often determined by the stereochemistry of β-hydroxyl groups. In type I polyketide synthases (PKSs), ketoreductase (KR) domains establish these stereocenters, making accurate prediction of K...

Score Reliability and Validity of a Mexican Dialect Spanish Translation of the Flourishing Scale With Mexican Earthquake Survivors

ABSTRACT The Flourishing Scale (FS) scores have demonstrated acceptable psychometric properties in general adult populations, but no previous research has validated its use among natural disaster survivors. This study examined the reliability, validity, and measurement invariance...

Case Study: Electrophoretic separation of bovine myosin heavy chain in samples stored long term at −20°C

ABSTRACT Objective Samples used for skeletal-muscle, fiber-type profiling are traditionally collected fresh and stored at −80°C until analysis. This study aimed to assess the vi-ability of using aged beef samples in prolonged storage at −20°C for muscle fiber typing. Materials an...

Living across landscapes: spatial and temporal strategies of crab-eating fox in structurally distinct environments

Abstract Habitat generalists exhibit broad ecological plasticity, yet their space-use strategies may be shaped by intrinsic traits and environmental heterogeneity. We investigated how crab-eating foxes ( Cerdocyon thous ) adjust spatial and temporal behaviors across two contrasti...

Role of Ion Channels in the Pathophysiology of SARS-CoV-2

In the pathophysiology of SARS-CoV-2, the critical role of ion channels has become increasingly evident during the COVID-19 crisis. This review offers a comprehensive analysis of the functions of ion channels, including viroporins, in both the viral life cycle and the host immune...

Non-coding regulatory variants in adolescent idiopathic scoliosis risk and pathogenesis

Adolescent idiopathic scoliosis is a common pediatric musculoskeletal disease that has significant impacts on childhood quality of life. Recent genome-wide association studies have identified dozens of genetic risk loci and hundreds of risk variants that primarily reside in non-c...