University of Exeter

Between Sex and Work: Regulating Webcamming Under the Platform Work Directive

Abstract This article examines the European Union Platform Work Directive (PWD) through the lens of webcamming, a form of platformised sex work largely excluded from regulatory debates on platform labour. Drawing on legal analysis and empirical research with webcam performers and...

Brain Injury in Domestic Abuse Related Death Reviews: Missed opportunities: a retrospective analysis of DARDR reviews

Domestic abuse related death reviews record events capable of injuring the brain for most of the people who died. Agencies almost never considered brain injury as a result, and what the reviews record is associated with abuse towards a person and not with abuse by them. A coded f...

Natural methane emissions feedbacks in MAGICC v. 7.6

Literature estimates of natural methane emissions, particularly from wetlands, have a wide range of uncertainty. Meanwhile, few Earth System Models (ESMs) explicitly model wetlands as a potential source of methane. As a result, Simple Climate Models that aim to emulate the behavi...

Sport, exercise, and physical activity in children with cardiovascular disease. A Clinical Consensus Statement of the European Association of Preventive Cardiology (EAPC) of the ESC, the Association of Cardiovascular Nursing & Allied Professions (ACNAP) of the ESC, and the Association for European Paediatric and Congenital Cardiology (AEPC)

Regular physical activity offers numerous benefits to children's health and well-being and is essential for reducing cardiovascular risk in children with cardiovascular disease. Despite increasing evidence supporting its benefits, many young patients remain insufficiently active...

Modelling spatial deficits in citizen science recording: a case study from UK butterflies

Abstract Citizen science data are increasingly used to infer species distributions and monitor biodiversity at large spatial scales. However, recording effort is often uneven across space, potentially biasing inferences about species’ distributions. We analysed 51,045 butterfly r...

An early shift from wetland-adjacent to upland farming in the Maya lowlands

Maize is a seed grain of global social and economic importance. It has a mutualistic relationship with humans that evolved in parallel with the decisions of farmers who intensified its production. This occurred in the context of climate change, human selection for improved variet...

Climate risk is not climate determinism

Climate economics necessarily simplifies the relationship between a changing climate and economic outcomes. Reduced-form relationships linking temperature to aggregate output compress heterogeneous hazards and their effects on labour, capital and productive systems into models th...

Microscopic dissection of chirality-induced spin selectivity in cryptochrome

Chirality-induced spin selectivity (CISS) has been proposed as a mechanism that enhances magnetic field sensitivity of radical pairs in magnetosensitive proteins, such as cryptochrome, through the recruitment of net spin polarization during radical pair formation and recombinatio...

Microbiome Dynamics During Translocation of the Critically Endangered Frog Craugastor ranoides

ABSTRACT Amphibian populations are declining, and species are going extinct due to habitat loss, climate change, and emerging infectious disease, prompting the increasing use of translocations as a conservation tool. Skin‐associated bacterial communities play a key role in amphib...

A qualitative exploration of information access and provision for cancer survivors experiencing chronic bowel symptoms after pelvic radiotherapy: informing a framework to guide improvements to information provision

Abstract Purpose For people living with and beyond cancer, access to clear, accurate, relevant information is crucial for meaningful participation in shared decision-making and is associated with better quality-of-life. Many cancer patients who undergo pelvic radiation experience...

Performance of a multi-cancer early detection test in the randomized controlled NHS-Galleri trial

Abstract The NHS-Galleri trial was a randomized controlled trial evaluating a multi-cancer early detection (MCED) test added to usual care. We reported elsewhere that the primary endpoint of a reduction in the incidence of stage III/IV cancer diagnoses in the intervention arm ver...

Effect of diet on cognition, mental health and wellbeing among adolescents: a systematic review

A healthy diet is crucial for adolescents’ health and wellbeing. Current literature on dietary intake and its association with cognition, mental health and wellbeing has mainly focused on younger children. The aim of this systematic review was to explore the evidence for these as...

Multifactorial and multiple component interventions for preventing falls in older people living in the community

RATIONALE: Multifactorial fall prevention interventions are those where intervention components are tailored to each person's individual fall risk factor profile. Multiple component interventions provide the same components to everyone. The evidence on the effects of these interv...

Lysosomal signaling pathways influence heart rhythm, and regulate atrial function

AIMS: In the heart, endogenous nicotinic acid adenine dinucleotide phosphate (NAADP) triggers lysosomal calcium (Ca2+) release to augment sarcoplasmic reticulum (SR) Ca2+ sequestration, producing larger Ca2+ transients. However, the role of lysosomal Ca2+ signals in pacemaker act...

Corporate Political Ideology and Environmental Strategy: Evidence From US Toxic Releases

ABSTRACT This paper examines whether corporate political ideology shapes firms' environmental strategy and realized environmental performance. Using US political donation data matched to facility‐level toxic releases from the Toxics Release Inventory from 2000 to 2014, we measure...

Modulating splicing in 5ʹ untranslated regions to treat rare haploinsufficient disease

Abstract Background Rare genetic disorders collectively impact over 300 million people worldwide, yet around 95% have no specific treatments. For the many rare disorders caused by haploinsufficiency, effective therapies need to upregulate protein expression. However, therapeutic...

Prevalence and penetrance of heritable retinoblastoma in two adult population cohorts: implications for genomic newborn screening

Abstract Retinoblastoma (Rb) is a rare childhood eye cancer. Almost half of cases are heritable, associated with germline RB1 pathogenic variants that pre-dispose to Rb and extraocular cancers. This study aimed to investigate the prevalence and penetrance of RB1 -heritable Rb in...

The Cloud Feedback Model Intercomparison Project (CFMIP) contribution to CMIP7

Cloud processes constitute one of the key uncertainties for climate change projections. The fourth iteration of the Cloud Feedback Model Intercomparison Project, CFMIP4, contributes to the Coupled Model Intercomparison Project phase 7 (CMIP7), by providing a set of global climate...

Morphology of the Devonian mandibulate arthropod Rhyniognatha and its implications for the timing of insect evolution

Abstract Insects are phenomenally diverse, yet their evolutionary origins remain poorly understood. The fossil Rhyniognatha hirsti from the Early Devonian Rhynie chert (ca. 408 Ma) has been widely accepted as the earliest insect and a crown-group pterygote (flying insect), based...

Implementing a peer-support programme for surgeons following adverse events

Introduction Despite the known impact of adverse events (AEs) for surgeons, and the potential for AE peer-support models, little is known about usefulness of AE peer-support initiatives in UK surgical settings. This study evaluated: (1) surgeons’ perceptions of current AE support...