University of East Anglia

Populism and academic freedom

Abstract Academic freedom empowers scholars to influence public discourse and debate, cultivate critical reasoning, discuss ideas that challenge traditional values, and impose a soft check and balance on governments. For those reasons, governments have specific preferences regard...

Institutionalizing portfolio entrepreneurship: the Venture Studio model

Venture Studios (VSs) are organizations that create start-ups by acting as founders or co-founders and operating through standardized venture creation processes conducted in parallel. To examine this organizational model and delineate its distinctiveness from others, we developed...

Krill defecation at depth reduces carbon flux attenuation in the Weddell Sea euphotic zone

Abstract. The Weddell Sea, Southern Ocean, is a highly productive location of deep-water formation and a globally important site of carbon sequestration. Here, the biological carbon pump is dominated by particulate processes (e.g. zooplankton faecal pellets and phytoplankton detr...

Epistemic politics of research funding: a social network analysis of knowledge production

Unequal power dynamics in knowledge production and dissemination are central to decolonisation debates, shaping whose knowledge is recognised, funded, and circulated. Knowledge produced in the Global North is often treated as universally applicable, while knowledge from the Globa...

Clinical integration of trabecular bone score in precision osteoporosis care: a position statement by the Egyptian academy of bone and muscle health

Abstract Background Dual-energy X-ray absorptiometry (DXA)-derived bone mineral density (BMD) has long been the gold standard for osteoporosis diagnosis, yet its inability to account for bone quality leads to a significant “sensitivity gap” in fracture risk prediction. This posit...

Electronic cigarettes for smoking cessation

RATIONALE: Electronic cigarettes (EC) are handheld electronic vaping devices that produce an aerosol by heating a liquid. People who smoke, healthcare providers, and regulators want to know if EC can help people quit smoking, and if they are safe to use for this purpose. This upd...

A conserved small RNA-generating gene cluster undergoes sequence diversification and contributes to plant immunity

Abstract Small RNA-mediated gene silencing contributes to plant immunity. The secondary small interfering RNA (siRNA) pathway promotes defense by silencing target genes in invading fungal and oomycete pathogens. Many secondary siRNAs are derived from transcripts potentially encod...

P1.200. Reducing Failure to Rescue Improves Long Term Survival After Oesophago-Gastric Cancer Surgery

Abstract Topic Esophageal Cancer: Surgical Treatment of Esophageal Cancer – early outcomes and complications Background Outcomes after oesophago-gastric cancer surgery have improved over time, and this is likely to be multifactorial. In addition to better oncologic treatments, sa...

Concurrent Peripheral Arterial Disease Predicts Re-Intervention Following Abdominal Aortic Aneurysm Repair: A Single-Centre Propensity Matched Retrospective Study

Purpose: Abdominal aortic aneurysm (AAA) and peripheral arterial disease (PAD) share common risk factors and may co-exist in patients undergoing AAA repair. The impact of concomitant PAD on clinical outcomes post AAA repair remains unclear. This study aims to evaluate whether con...

P1.201. Textbook Outcome After Oesophago-Gastric Cancer Surgery: Temporal Change Over 24 Years and Association With Survival

Abstract Topic Esophageal Cancer: Surgical Treatment of Esophageal Cancer – early outcomes and complications Background Outcomes after oesophago-gastric cancer surgery have improved over the last two decades, but it is unclear whether this reflects fewer complications, improved s...

Arming the archipelago: explaining A2/AD divergence in the South China Sea

How do secondary powers develop anti-access/area denial (A2/AD) capabilities when facing asymmetric threats? This article explains variation in Southeast Asian maritime defense strategies through a novel framework that distinguishes between anti-access (A2) and area denial (AD) b...

Genomic catalogue of giant viruses reveals expanded diversity and functional potential

Nucleocytoplasmic large DNA and Mirusviricota viruses exhibit taxonomic richness which continually expands due to metagenomic sequencing. Here we curate a database of giant virus metagenome-assembled genomes (GVMAGs V2), comprising 8,508 species-level representatives from 18,727...

Habitat insularization alters taxonomic and functional beta diversity of understorey birds in Amazonian forest islands

Abstract Habitat fragmentation can profoundly alter the composition of biological communities, modifying patterns of beta diversity among areas. These effects are manifested through different components of beta diversity: differences in richness, which reflect variation in specie...

When education sticks: early imprints and sociopreneurship in emerging economies

This study examines how entrepreneurship education and training (EET) influences sociopreneurship in emerging economies. Drawing on dynamic imprinting theory, we argue that EET received at different stages of life leaves imprints of unequal durability, and that the expression of...

Retinoic Acid Receptor γ Is a Ligand-Activated Gatekeeper to Stem Cell Developmental Progression

RARγ is expressed during embryogenesis by stem/primitive progenitor cells, indicating a role in controlling their development. Supporting this view is that a physiological level of 10 nM of the RARγ agonist AGN205327 blocked stem/progenitor cell differentiation during zebrafish e...

Healthcare professionals’ knowledge and experiences of identifying and supporting young carers: a literature review

Young people who have caring responsibilities, usually for a family member, can experience a range of adverse mental and physical health outcomes. Healthcare professionals have a crucial role in providing these individuals with support, however there is inadequate recognition and...

Awake craniotomy for drug-resistant non-oncological epilepsy: a systematic review of feasibility, reported safety, and seizure outcomes

Abstract Introduction Complete resection of the epileptogenic zone offers the best chance of seizure control in patients with drug-resistant epilepsy. However, surgical management remains challenging when the epileptogenic zone is located within or adjacent to eloquent brain regi...

Incidence and relative risk of negative outcomes of psychological interventions for pediatric posttraumatic stress disorder: a systematic review and meta‐analysis of randomized controlled trials

Background Negative outcomes of psychological treatments for pediatric posttraumatic stress disorder (PTSD) have been underresearched. Although reporting has increased over the years, a comprehensive systematic review and meta‐analysis is lacking. Methods We conducted a preregist...

Applying the International Classification of Functioning, Disability and Health to Classify Upper Limb Outcome Measures in Stroke Rehabilitation: A Construct-Driven Perspective

INTRODUCTION: Accurate evaluation of upper limb recovery after stroke is essential for guiding rehabilitation targeting specific impairments and activity limitations. To achieve this, outcome measures must clearly reflect what they assess, whether neuromuscular impairments or act...

ZPY-CpG-Ch, a broad coverage vaccine against Streptococcus pneumoniae

Existing licensed pneumococcal vaccines, including Prevnar-13 and its higher-valency successors, have played a major role in reducing invasive pneumococcal disease worldwide. However, their effectiveness is increasingly threatened by the rise of multidrug-resistant strains and th...