University of East Anglia

Well-being in digital-free tourism: A mixed-methods rhythmanalysis

Tourism research has largely treated well-being as a motivation or outcome, neglecting how it unfolds in-situ and relying on self-report data. Through a mixed-methods rhythmanalysis, this study examines how well-being emerges and evolves in digital-free tourism. Following 23 part...

A broad-host-range Rhizobium rhizogenes strain enables transient expression across diverse crop species

Agrobacterium -mediated transient expression has revolutionised plant research, enabling numerous landmark discoveries across diverse areas of plant biology. Yet this powerful approach remains largely confined to solanaceous species, leaving most economically important crop famil...

Belonging for Women, LGBTQ+ and Black and Ethnically Minoritised People With Learning Disabilities: Findings From a Qualitative, Co‐Produced Study in England

ABSTRACT Belonging is a key aspect of human experience. This qualitative study examined where diverse people with learning disabilities feel belonging, what shapes belonging and how it affects their health. Focus groups were held with people with learning disabilities across Engl...

Clinical Outcome Differences in Asia Versus Non-Asia Intracerebral Hemorrhage: IPD Analysis From BP-Lowering Clinical Trials

BACKGROUND: Evidence of regional differences in clinical outcomes after intracerebral hemorrhage (ICH) is still scarce. We quantified differential outcomes and response to early intensive blood pressure lowering treatment by region in the Blood pressure in Acute Stroke Collaborat...

Intensification of near-inertial currents in the Atlantic Ocean over the past two decades

Near-inertial currents (NICs) play a key role in surface material redistribution and ocean mixing, yet their long-term variability remains poorly known. Using in situ current measurements from surface drifters, we provide observational evidence for a pronounced intensification of...

Antarctic sea ice response to meltwater due to Antarctic ice sheet mass loss in a multi-model ensemble

Abstract. We present the first multi-model study of the Antarctic sea ice response to enhanced meltwater due to dynamic mass loss from the Antarctic ice sheet. This meltwater flux (and its future increase under global warming) is not included in the most recent state-of-the-art c...

Optimisation of Baby, Me & NRT: a nicotine replacement therapy adherence intervention for pregnancy

OBJECTIVE: Nicotine Replacement Therapy (NRT) is effective for quitting smoking, but pregnant women appear to benefit less than others. Likely reasons include poor adherence due to erroneous beliefs about NRT. We developed a theory-guided, blended interpersonal and digital NRT ad...

Implementation of electronic signposting to interventions that prevent cancer: A realist review

Uptake of evidence-based interventions that prevent cancer is very low. Electronic signposting using digital messages sent via electronic healthcare systems is increasingly utilised to improve service reach and uptake. However, theory for optimising the implementation of electron...

Limits of Memory-Assisted Coherence in Cavity-Embedded Molecules

Abstract Strong light–matter coupling in optical cavities is being widely explored as a strategy for modifying molecular dynamics and enhancing coherence. At the same time, structured vibrational environments can exhibit non-Markovian memory that promotes information backflow and...

Relating object memory to word learning: Data from a new test of toddlers' object recognition

Abstract Learning names for concrete objects, which dominate early vocabularies, relies on visual processes such as object recognition and memory for previously named objects. We examined the relation between memory for pairs of familiar and novel objects and early vocabulary dev...

Generalized Nonlinear Bayesian Pulsar Timing with ENTERPRISE

Abstract We use the Bayesian methods in the ENTERPRISE package to examine the fully general parameterization of pulsar timing models in tandem with noise. We investigate four pulsars, PSRs J1600–3053, J2043+1711, J0740+6620, and J1640+2224, through the lens of Bayesian timing. We...

Impact of a Mediterranean diet and physical activity intervention on the gut microbiome and faecal metabolites: findings from the MedEx-UK randomised controlled trial

Abstract Diet and physical activity (PA) are potential modulators of the gut microbiome, although research findings are inconsistent, and few studies have explored their combined effects. This study used data from ninety-three participants (forty-seven with pre- and post-interven...

Systemically delivered Bacteroides thetaiotaomicron -derived bacterial extracellular vesicles inhibit primary and metastatic melanoma growth

ABSTRACT The gut microbiome can contribute to anti-tumor immunity and cancer therapy responses, but translating live microbe-based interventions remains challenging due to safety, controllability, and delivery constraints. Bacterial extracellular vesicles (BEVs) are an attractive...

Gestational Changes in Placental Iron Homeostasis are Associated With Ferroptosis‐Associated Redox Signaling and Trophoblast Behavior

Well-regulated trophoblast proliferation, migration, invasion, and cell turnover are essential for normal placental development in humans and rodents. Given the established role of oxidative stress in placentation and the redox activity of iron, we investigated whether ferroptosi...

Labeling and Folding Multi-Labeled Trees

In 1989 Erdős and Székely showed that there is a bijection between (i) the set of rooted trees with \(n+1\) vertices whose leaves are bijectively labeled with the elements of \([\ell]=\{1,2,\dots,\ell\}\) for some \(\ell \leq n\), and (ii) the set of partitions of \([n]=\{1,2,\do...

Treat (the whole of) me: a systematic review and qualitative meta-ethnographic synthesis of the experiences of women with POP, SUI or mesh complications in the context of surgical treatment

Abstract Background Stress Urinary Incontinence (SUI) and Pelvic Organ Prolapse (POP) are common pelvic floor disorders that may significantly impact women’s quality of life. Surgical interventions are available to treat these conditions, some using synthetic mesh. Whilst most wo...

Negotiating multiple faces in social work spaces: ethnographic insights into the performance of professional identity across adult and child and family teams

This article explores how professional identity is enacted in social work practice, drawing together two ethnographic studies of adult and child and family social care services in Scotland and England. Through ethnographic observation, interviews, and reflective fieldnotes, the s...

Effectiveness of Interventions for Reducing Loneliness Among Adult Cancer Survivors: A Systematic Review and Meta-Analysis

Background/Objectives: Loneliness in adult cancer survivors is a frequent and disruptive psychosocial sequela with important consequences for overall health. Psychosocial interventions designed to address this issue are crucial. This systematic review and meta-analysis aimed to e...

Approved mental health professionals (AMHPs) decision-making regarding detention of adults diagnosed with borderline personality disorder (BPD)

The present study explored the decision-making of Approved Mental Health Professionals (AMHPs) for compulsory admissions for Borderline Personality Disorder (BPD) under the Mental Health Act, 1983 (MHA). A sample of 101 AMHPs were recruited from across England and randomised to a...

The Onychomys pangenome reveals the unique molecular adaptations that confer toxin resistance

Abstract Background Predatory grasshopper mice ( Onychomys sp.) have co-evolved resistance to painful and lethal neurotoxins produced by their scorpion prey. Previous studies have reported that structural and functional modifications of the sodium channel Nav1.8 block the effect...