University of Delaware

The Use of Clonidine in Patients With ADHD and Comorbid ODD

Background Attention-deficit/hyperactivity disorder (ADHD) co-occurs with oppositional defiant disorder (ODD), which lacks an approved treatment. Clonidine, an alpha-2 agonist approved for ADHD, is used off-label to target aggression, impulsivity, and hyperactivity, though eviden...

Death and chemotaxis: Bacterial chemotaxis enables collective escape from phage predation

Bacteriophages (“phage”) are viruses that prey on bacteria in diverse environments, from biological tissues to soils. In many of these environments, bacterial hosts are constantly migrating, yet how bacterial migration is influenced by phage predation remains poorly understood. U...

Source Identification via Path-Wise Gradient Estimation

Abstract. In the context of PDE-constrained optimization theory, source identification problems traditionally entail particles emerging from an unknown source distribution inside a domain, moving according to a prescribed stochastic process, e.g., Brownian motion, and then exitin...

Nd isotopes as a paleocirculation tracer: consideration of sedimentary context and assessment through a north-south Atlantic transect

Authigenic neodymium (Nd) isotope ratios have been extensively used over the past two decades to reconstruct past changes in the global ocean circulation. Nevertheless, their effectiveness as a water mass tracer is currently strongly disputed based on the potential for modificati...

Deeply nonlinear magnon-photon hybrid excitation

We investigate the microwave-power dependence of magnon-photon coupling in a yttrium iron garnet-sphere/split-ring resonator hybrid system at room temperature and demonstrate that nonlinear spin-wave interactions suppress the coupling through power-induced dissipation of magnetos...

Mapping the Landscape of State-Level Cybersecurity Planning: An Analysis of 50 U.S. States from 2015 to 2021

The cybersecurity planning landscape across U.S. state governments is both critically important and surprisingly understudied. This article provides a systematic document-based comparative analysis of publicly available cybersecurity planning materials across all 50 U.S. states....

High diversity but limited expression of biosynthetic gene clusters in a peatland microbial community

Abstract The in situ relevance of biosynthetic gene clusters (BGCs) remains poorly understood. We apply meta-omics to characterize BGC diversity and activity along a peatland redox gradient. From seven metagenomes, we recover 9,694 BGCs, spanning diverse taxa, most lacking close...

Implementation-Oriented design in CARICOM regional policies: A theory informed configurational evaluation

This study evaluates implementation-oriented design in nine Caribbean Community (CARICOM) regional policy documents, a governance setting marked by fragmented authority and sovereignty constraints. Using fuzzy-set Qualitative Comparative Analysis (fsQCA) as a configurational mapp...

A new species of planthopper in the genus Bothriocera (Hemiptera: Auchenorrhyncha: Cixiidae) from Osa peninsula, Costa Rica on palms (Arecaceae)

Recent survey efforts on palms (Arecaceae) in Costa Rica have resulted in the discovery of many new species of cixiid planthoppers. A recent expedition resulted in the discovery of a new species, Bothriocera aurea sp. nov., from palms on the Osa peninsula. Herein, the novel taxon...

Programmable Assembly of Higher‐Order DNA Nanostructures from Microbial ssDNA Staple Libraries

Bottom-up manufacturing of structural DNA nanotechnology requires a long single-stranded DNA (ssDNA) scaffold and hundreds of short (∼30 nt) ssDNA staples. However, large-scale production is limited by the high cost and environmental impact of solid-phase chemical staple synthesi...

Frontline Perspectives: WIC Clinic Emergency Preparedness Following Hurricane Helene

Abstract Introduction The Special Supplemental Nutrition Program for Women, Infants, and Children (WIC) targets nutrition and health behaviors of high-risk populations. WIC is administered by the U.S. Department of Agriculture and provides services in 4 areas: nutrition education...

Harnessing the Microbial Iron Redox Chain: Liquid Organic Acid Fertilizer and EDTA-Fe Drive Unexpected Cadmium Passivation in Alkaline Upland Soils

Abstract The immobilization of cadmium (Cd) in weakly alkaline upland soils, a major agricultural system in northern China, remains a challenge. This study examined whether liquid organic acid (OA) fertilizer and EDTA-Fe could stimulate Fe redox to stabilize Cd. OA fertilizer (ac...

Preliminary investigation into the maternal‐embryo stable isotope dynamics and nutrient routing in an oophagous elasmobranch, the Common Thresher Shark ( Alopias vulpinus )

Abstract Two opportunistic sampling events were used to analyse the isotopic composition of different tissue constituents (protein and lipid) to explore maternal investment routing pathways from pregnant Common Thresher Sharks ( Alopias vulpinus ) to their near‐term embryos. Prot...

Mixed Valence-Driven Phase Evolution and Property Tuning in PdSe2

Abstract Layered palladium diselenide (PdSe2) is an emerging functional dichalcogenide whose structural flexibility enables tunable electronic, magnetic, and transport properties. However, controlled access to compositionally substituted and metastable polymorphs remains challeng...

Comparative evaluation of different sol–gel processed M-type barium hexaferrite on structural and antimicrobial efficacy

Barium hexaferrite has gained increasing attention for biomedical applications, including antimicrobial coatings and targeted drug delivery alongside its established use in magnetic solid-state devices. Therefore, understanding how synthesis routes influence its formation and bio...

Inositol Hexakisphosphate Promotes Open Pore State in HIV Capsid Protein Lattice by Reconfiguring Subunit Contacts

Abstract The mature human immunodeficiency virus (HIV-1) capsid is composed of approximately 250 capsid protein hexamers, each containing a central pore delimited by a β-hairpin and an α-helix from each monomer. The cellular metabolite inositol hexakisphosphate (IP6) binds this p...

Satellite based inference for disaster induced power outages using daily nighttime light observations

Abstract Power systems are vital to society, but remain vulnerable to natural disasters that cause widespread outages. Satellite-captured nightlights offer a global opportunity to monitor electricity disruptions. Prior work has typically relied on aggregating nightlight observati...

Hygrothermal durability of fiber anchors for externally bonded CFRP strengthening of reinforced concrete members

Externally bonded carbon fiber-reinforced polymer (EB-CFRP) sheets are now widely used for strengthening and repair of reinforced concrete structures. To mitigate debonding failure, FRP sheets are often mechanically anchored to the substrate using fiber anchors, which have gained...

Generative AI for NSF Grant Prewriting: Zero-Shot Protocol Prompting for Tactical Competitive Intelligence

Libraries are increasingly positioned to support faculty grant development, yet proposal-prewriting assistance remains uneven across institutions, particularly where research-development infrastructure is limited. This article presents a practical generative AI workflow for trans...

Walking Speed Can Be Modulated on an Adaptive Split-Belt Treadmill

Adaptive treadmills (ATMs) that change speed based on the users’ gait mechanics can allow for healthy stride-to-stride variability observed during overground walking while maintaining the benefits of traditional treadmill training for gait rehabilitation. To enable unilateral mod...