University of Cincinnati Medical Center

Empowering leaders, empowering teams: fostering wellness through leadership

Pediatric radiology is deeply meaningful work, yet increasing workplace stress and burnout threaten workforce engagement, retention, and the delivery of high-quality patient care. Historically, many wellness initiatives have focused on individual-level interventions, such as resi...

Prescription Patterns of Cardiovascular Medications in the Adolescent and Adult Population With Fontan Circulation—A Report From the Multicenter Single Ventricle Outcomes Network

BACKGROUND: There are limited data on prescription patterns in adolescents and adults with Fontan circulation. METHODS: We conducted a retrospective analysis of patients 13 years of age and older enrolled between 2022 and 2024 in the Fontan Outcomes Network (now SV-ONE [Single Ve...

Supporting clinical guidelines for opioid conversion to methadone and tapering to prevent withdrawal in critically ill children using physiology based pharmacokinetic modeling and simulation

Long-term opioid use is common in critically ill children and can cause withdrawal symptoms at discontinuation. To avoid withdrawal, short-acting opioids are usually converted into a long-acting drug, such as methadone, which is then carefully tapered. However, the exact conversi...

Responding With Evidence and Access for Childhood Headaches ( REACH ) study: A comparative effectiveness trial of cognitive behavioral therapy monotherapy versus combined cognitive behavioral therapy–pharmacotherapy with amitriptyline for the prevention of childhood migraine—The study protocol

Migraine is one of the most common chronic health problems in children and adolescents, resulting in high levels of functional disability. Symptoms frequently persist into and impact the course of adulthood for affected individuals. Current practice recommendations include a comb...

Household Food and Nutrition Security Among Publicly Insured Families of Hospitalized Children

OBJECTIVE: To characterize household food and nutrition security among families during hospitalization and examine associations with government benefits and neighborhood conditions. We hypothesized Special Supplemental Nutrition Program for Women, Infants, and Children (WIC) or S...

Machine Learning Guided Discovery of Microbiome Metabolites That Inhibit HDAC

Abstract Histone deacetylase (HDAC) is a family of key epigenetic regulator implicated in inflammation, metabolism, and cancer. Microbiome metabolites can modulate host histone acetylation, yet systematic identification of metabolites that target HDAC remains limited. Here we pre...

Precision diagnostics in pediatric bone tumors: practical considerations and practice updates

Pediatric bone tumors are increasingly sampled through image-guided biopsies. Evolution of molecular and diagnostic adjuncts have enabled diagnosis of these challenging lesions with limited diagnostic tissue. Radiologic correlation remains critical in the evaluation of these lesi...

The informativeness of stock price at dual-class firms

Abstract We examine whether disproportionate insider control, or the divergence between insider voting and cash flow rights at dual-class firms, influences the extent to which stock price reflects information about future firm performance. We find that current returns incorporate...

Global variability in cardiovascular care of pediatric cancer patients and survivors: survey results from the International Cardio Oncology Society (ICOS)

Childhood cancer survivors (CCS) are at elevated risk for cardiovascular disease due to cardiotoxic cancer therapies. Different international guidelines and recommendations for follow-up were published. However, global practices surrounding cardiovascular risk assessment, screeni...

Identifying Contextual Factors affecting Hospital In Home Program Implementation within the Veterans Health Administration

Abstract Background and Objectives Understanding the factors that enable or hinder successful implementation is essential for improving patient outcomes. Hospital in Home (HiH) programs provide hospital-level care in patients' homes to reduce hospitalization, enhance satisfaction...

The History of Neurosurgery at New York Medical College and Westchester Medical Center

The history of the Department of Neurosurgery at the New York Medical College (NYMC) began in New York City in the early 20th century. The purpose of this manuscript is to educate on the history of neurosurgery at NYMC and Westchester Medical Center (WMC) from its early beginning...

Program Directors’ Varied Conceptions of Practice Readiness

BACKGROUND: Residency graduates must be "practice ready" by the time they leave training. This study explored how pediatric residency program directors view their role and responsibility in determining practice readiness and examined how characterizations of practice readiness di...

The human cytomegalovirus vGPCR UL33 is essential for efficient lytic replication in epithelial cells

ABSTRACT Human cytomegalovirus (HCMV) is a β-herpesvirus that is ubiquitous in the human population. HCMV has the largest genome of the human herpesviruses and encodes an array of genes that affect pathogenesis in different cell types. Given the ability of HCMV to replicate in a...

Sociodemographic and Clinical Factors Associated With Nirsevimab Receipt Among Children Aged Younger Than 20 Months in the New Vaccine Surveillance Network in 2023 to 2025

OBJECTIVES: We aim to evaluate the association of sociodemographic and clinical factors with nirsevimab receipt among children with medically attended acute respiratory illness (ARI) across multiple seasons and beyond birth hospitalization. PATIENTS AND METHODS: We included nirse...

Effect of Perioperative Tranexamic Acid on Blood Loss in Posterior Acetabular Fracture Fixation

OBJECTIVE: To evaluate the impact of perioperative intravenous (IV) tranexamic acid (TXA) on total blood loss (TBL) and transfusion requirements in patients who underwent acetabular fracture fixation (AO/OTA 62) via a posterior surgical approach. The authors hypothesized that pat...

Scope, Scholarship, Sustainability: Unpacking the Pediatric Hospitalist Workforce

As the landscape of pediatric hospital medicine (PHM) has evolved, the role of the hospitalist has become increasingly diverse. The broad scope of practice encompasses an assortment of clinical and nonclinical roles, with varied expectations in workloads, shift types, and adminis...

TRANCE is a unique marker of chronic pancreatitis in children

BACKGROUND Elucidating immune signals through well-defined cohorts of pediatric acute pancreatitis (AP) and chronic pancreatitis (CP) patients is critical. This study aimed to evaluate plasma chemokine and cytokine levels in pediatric participants with CP, compared with AP and he...

Clinical and mechanistic validation of skin gravitational stretchability as a new metric for skin aging assessment

Maintaining the skin’s dynamic resilience and youthful compliance is crucial to resisting the visible signs of aging, particularly sagging. We modified a previously reported non-invasive tensile method that simulates the gravitational pull on facial skin for the direct measuremen...

Variation in In-Hospital Emergency Transfer Rates Across Pediatric Hospitals

BACKGROUND: Clinical deterioration with late escalation, termed emergency transfer (ET), is a key safety metric. However, national benchmarking is limited by variable definitions. We sought to estimate pooled ET rates and assess variation across pediatric hospitals. METHODS: We p...

Continuous Publishing as Next Step in Continuous Improvement at Hospital Pediatrics

We are excited to announce that Hospital Pediatrics has moved to a continuous publishing model. What is continuous publishing? It is a relatively new model in which articles are published shortly after acceptance versus the historical model of publication occurring when space was...