University of Chinese Academy of Sciences

Magnetic Field‐Modulated Ion Migration in Electrochemical Cells

Ion migration within electrochemical cells fundamentally governs interfacial reaction kinetics, charge transport, and the formation of electric double layers, thereby critically determining the overall performance of electrochemical devices. However, conventional regulation strat...

siRNA-mediated mismatch repair disruption synergizes with oxaliplatin to restore immune surveillance in microsatellite-stable colorectal cancer

Proficient mismatch repair/microsatellite-stable colorectal cancer (pMMR/MSS CRC), which represents the majority of clinical cases, exhibits low tumor mutational burden and minimal responsiveness to immune checkpoint blockade. Disrupting the MMR system has been shown to resensiti...

Need-responsive accessibility supports equitable sustainable development and reshapes migration as evolving human needs

Realizing the Sustainable Development Goals’ commitment to “leave no one behind” requires accessibility that responds to evolving human needs, yet prevailing accessibility assessments remain static and sector-specific, overlooking hierarchical need evolution and behavioral feedba...

The comprehensive detection of hemoglobinopathy variants via long-read sequencing

ABSTRACT BACKGROUND The genetic complexity of hemoglobin genes, characterized by high GC content and homologous sequences, poses significant challenges for detecting hemoglobin variants in clinical settings. METHODS A long-read indexed PCR method utilizing the novel CycloneSEQ na...

Chiral Iridium(III)Microcrystals with Mechano-TunableCircularly Polarized Luminescence

Abstract Multidimensional optical materials are of interest for high-security information encryption and anticounterfeiting, whereas conventional single-channel luminescent systems have low coding capacity and limited security. The combination of mechanochromic luminescence (MCL)...

Changes of Precipitation Extremes and Persistence Over the Tibetan Plateau Projected by a Convection‐Permitting Model

Abstract Extreme precipitation has increased over many regions in recent decades, but the simulation and projection remain particularly challenging over complex terrains, such as the Tibetan Plateau (TP). Here, we investigate the future changes in precipitation extremes and persi...

Constructing zero-external-pressure high-performance sulfide all-solid-state pouch cells via asymmetric interfacial electrophilicity

Sulfide solid electrolyte (SSE)–based all-solid-state lithium metal batteries (ASSLBs) attract great attention owing to high ion conductivity and mechanical deformability. However, the practical application of pouch cells is hindered by their heavy reliance on high-external-press...

Synergistic Dual‐Channel Charge Separation in Cr‐TiO 2‐x for Solar H 2 O 2 Synthesis

ABSTRACT Solar‐driven hydrogen peroxide (H 2 O 2 ) synthesis offers a sustainable alternative to the energy‐intensive anthraquinone process, yet its efficiency is fundamentally constrained by the inability to simultaneously harness photogenerated electrons and holes in a balanced...

Synergistic Dual‐Channel Charge Separation in Cr‐TiO 2‐x for Solar H 2 O 2 Synthesis

ABSTRACT Solar‐driven hydrogen peroxide (H 2 O 2 ) synthesis offers a sustainable alternative to the energy‐intensive anthraquinone process, yet its efficiency is fundamentally constrained by the inability to simultaneously harness photogenerated electrons and holes in a balanced...

Changes in the tropical rainfall seasonal cycle dominated by mesoscale convective systems

Global warming is reorganizing atmospheric circulation and hydroclimate, and tropical rainfall is a key manifestation of this response. Yet how these large-scale changes are translated into the tropical rainfall seasonal cycle remains uncertain because organized convection, which...

Building a Physics-Aware AI Ecosystem for Solid-State Hydrogen Storage Materials

Abstract Hydrogen storage remains a central bottleneck for scalable hydrogen energy systems due to the multiscale and coupled nature of the thermodynamics, kinetics, and microstructural evolution of hydrogen storage materials (HSMs). Although artificial intelligence (AI) has acce...

Atmospheric Blocking Pattern as the Primary Driver of Subseasonal Greenland Ice Sheet Summer Melt Variability

ABSTRACT The anomalous summer melting of the Greenland Ice Sheet (GrIS) is one of the key signals of ongoing climate system changes. The complex spatiotemporal characteristics of GrIS and its impacts on global sea‐level rise have attracted increasing attention. Although previous...

Sustainable Recovery of Platinum Group Metals via Oxysalt Phase Reconstruction and Subsequent Deep Eutectic Solvent Leaching

Abstract The recycling of platinum group metals (PGMs) underpins sustainable development across semiconductors, new energy devices, and catalytic materials. Efficiently enriching and extracting these sparsely distributed PGMs from solid wastes such as spent catalysts still pose a...

GPU-accelerated finite-element method for the three-dimensional unstructured mesh atmospheric dynamic framework

Abstract. The three-dimensional unstructured-mesh finite-element atmospheric dynamical framework is gaining significance owing to its flexibility in representing complex topography and capability for multi-scale simulations in high resolutions. However, this framework has substan...

EEG-Neurofeedback Targeting Gamma Oscillations at the Parieto-Occipital Region Reduces Pain Perception

Pain is closely associated with both spontaneous and stimulus-evoked gamma oscillations, which differ in their phenomenology and their relationship to pain perception. These associations make gamma oscillations a promising target for pain interventions, such as closed-loop real-t...

Kinetically ProgrammedThermoresponsive PolyethyleneGlycol Shedding from Lipid Nanoparticles Improves mRNA Delivery

Abstract Polyethylene glycol (PEG) can stabilize nanoparticles and facilitate transport across biological barriers, yet the same PEG layer suppresses cellular uptake─a trade-off known as the PEG dilemma. Current strategies seek to overcome this limitation by enabling PEG shedding...

A Novel n-Hexadecane-Degrading Bacterium Provisionally Named “Thermalkanevorax longiformis” Isolated from a Deep-Sea Hydrothermal Vent

Hydrothermal systems contain diverse alkanes derived from biological and geological processes, providing potential carbon and energy sources for microorganisms. However, cultivated thermophilic alkane-utilizing bacteria from hydrothermal environments remain poorly characterized....

ODARRL: Obstacle- and Disturbance-Aware End-to-End Residual Reinforcement Learning for Underwater Robot Trajectory Tracking with Obstacle Avoidance

ROVs are essential for marine exploration and underwater operations, yet conventional teleoperation relies heavily on skilled human operators, and many autonomous methods stop at high-level planning rather than low-level actuation, limiting robustness in disturbed and cluttered e...

Accelerating theDiscovery of Deep-Ultraviolet NonlinearOptical Materials by Combining Machine Learning Interatomic Potentialswith First-Principles Calculations: A Case of LiB2O3F

Abstract Discovering deep-ultraviolet (deep-UV) nonlinear optical (NLO) crystals is hampered by the vast structural search space and the cost of first-principles screening. Here, we establish an integrated framework coupling machine learning interatomic potential (MLIP) construct...

Plant species identification by genome skimming across the vascular plant tree of life

Summary Accurate species identification is essential for biodiversity conservation and sustainable use, yet standard plant DNA barcoding often fails to achieve species‐level resolution. We present a large‐scale empirical evaluation of genome skimming as a tool to improve plant sp...