University of Chile

Stacking Ensemble Learning for Copper Grade Prediction at the Sungun Porphyry Copper Deposit: Statistical Performance Versus Geological Coherence

Mineral resource estimation has traditionally relied on geostatistical techniques such as Ordinary Kriging (OK), which explicitly account for spatial continuity but may introduce smoothing effects and require extensive manual parameterization. In parallel, Machine Learning (ML) m...

From Open Sun to Advanced Hybrid Systems: A 50-Year Journey of Solar Drying Evolution Through Bibliometric Insights

Solar drying is a foundational dehydration technique that has evolved significantly from its empirical origins to become a sophisticated engineering discipline. This study presents a comprehensive bibliometric mapping of 50 years of solar drying research (1976–2025) using 4384 do...

Collective phases in overdamped magnetic self-propelled spherocylinders

We study the collective dynamics of self-propelled spherocylinders carrying magnetic dipole moments in two dimensions. Magnetic interactions are modeled as two opposite monopoles ± Q separated by a distance ℓ along the particle orientation axis, an idealized dumbbell model that r...

Active nuclease inhibition over passive freezing secures the genomic archive of fish eye lenses

Abstract Fish eye lenses offer a chronological archive of individual life histories and preserve genomic DNA. However, integrating ecological and genetic data is hindered by post‐mortem nuclease degradation, and standardized DNA preservation protocols for this tissue remain undef...

PEEK Pectus Bar: Evaluation of a New Material for Pectus Excavatum Repair in Children and Teenagers

The Nuss procedure for Pectus Excavatum repair has relied on metallic bars for the past 3 decades. The technical efforts have focused on the improvement of stability and the reduction of the associated risks. However, some challenges still remain, like metal ion release, thoracic...

Alveolar bone loss and dentoalveolar remodelling in pre-Columbian human remains from northern Chile

Alveolar bone loss in archaeological human remains is a composite skeletal outcome influenced by biological ageing, occlusal function, compensatory eruption, antemortem tooth loss, and inflammatory destruction. Accordingly, cementoenamel junction–alveolar crest (CEJ–AC) distance...

Message in a bottleneck: Nested founder effects from French Polynesia to Rapa Nui and Hawaiʻi

Founder effects can lead to strong, population-specific allele frequency differentiation, including autosomal recessive conditions. Their characterization in European-descent groups, such as the Finnish and Amish, has resulted in actionable genetic tests for each. We show that Po...

Embryos resolve the enigmatic origin of the theropod wishbone

The origin of the avian wishbone (furcula)—present since theropod dinosaurs—remains unsolved. Its homology is still debated, with competing hypotheses proposing derivation from the clavicles, the interclavicle, or both. To obtain comparative developmental evidence, we studied oss...

Trophic position structures physiological trade-offs between metabolic and detoxification pathways in sympatric passerines

Abstract Resource use links ecological context to organismal performance, yet whether dietary breadth or trophic position is more closely associated with physiological state in wild birds remains unclear. We used a natural trophic gradient in a sympatric passerine assemblage to t...

Timing and trajectory of acute kidney injury predict mortality in alcohol-associated hepatitis: A multinational cohort study.

BACKGROUND: Acute kidney injury (AKI) is common in alcohol-associated hepatitis (AH) and associated with poor outcomes, yet the prognostic implications of AKI timing and early renal trajectory remain unclear. METHODS: In this prospective multicenter cohort from the Global AlcHep...

On the double-adiabatic equations in the relativistic regime

We revisit the double-adiabatic evolution equations and extend them to the relativistic and ultrarelativistic regimes. We analytically solve the relativistic, time-dependent drift kinetic equation for a homogeneous, magnetised, collisionless plasma and obtain a solution explicitl...

Impaired Regulated Exocytosis and GLUT4 Trafficking in Dysferlin-Deficient Human Myoblasts: A Pilot Study

Background/Objectives: Dysferlinopathies are inherited muscular dystrophies caused by DYSF mutations that lead to progressive muscle degeneration. Proteomic analyses of patient muscle reveal altered abundance of proteins involved in regulated exocytosis and energy metabolism, ref...

When does brand purpose stop creating brand equity? The moralizations trap of strategic self-sabotage

Purpose This study aims to conceptualize article challenges the assumption that brand purpose inherently strengthens brand equity. Drawing on hybrid logics theory, brand meaning theory and event system theory, the study examines the conditions under which brand purpose shifts fro...

Standards for practical management of drug hypersensitivity reactions to intravenous drugs and proactive early allergy involvement before referral: A WAO Statement

Hypersensitivity reactions to intravenous therapies—including antibiotics, chemotherapeutics, biologics, anesthesia agents, and contrast media—pose significant challenges in acute care settings. These reactions often occur outside the purview of allergy specialists, leading to de...

Short-term macronutrient-specific diets induce distinct metabolic changes detectable in blood and saliva

Background Tools to non-invasively capture dynamic metabolic responses to diet in humans remain limited. Saliva has emerged as an accessible complementary biofluid, but its responsiveness to diet-induced metabolic adaptations remains insufficiently characterized. Methods In this...

Seed storage reduces the optimal temperature for germination of wild castor seed accessions

Castor plant ( Ricinus communis L.) is a non-edible raw material of importance for several industries, including cosmetics, pharmaceuticals, and energy. However, its commercial production is limited by seed dormancy, which affects germination rate and germination temperature unde...

Association between the accumulation of unhealthy lifestyle factors and musculoskeletal pain in older adults

Abstract Background Although previous studies have examined individual lifestyle behaviors in chronic musculoskeletal pain outcomes, the cumulative impact of unhealthy lifestyle behaviors remains unclear. Objective To assess whether the accumulation of unhealthy lifestyle behavio...

Gas-Phase Photocatalytic Nitrogen Conversion over Nanostructured Metal-Modified Fe2O3: The Role of Surface Chemistry, Band Alignment, and Hydrogen Activation

Abstract Photocatalytic nitrogen conversion over iron oxide-based materials remains challenging, particularly under gas-phase conditions, where reaction pathways and product distributions are poorly understood. Herein, nanostructured Fe2O3 and metal-modified Fe2O3 photocatalysts...

Increasing rates of hospitalizations with autoimmune hepatitis as the primary discharge diagnosis in Chile: a national analysis from 2001 to 2024

Autoimmune hepatitis (AIH) is a chronic immune-mediated liver disease with limited epidemiological data from Latin America. We aimed to evaluate temporal trends, demographic characteristics, and clinical outcomes of hospitalizations with AIH as the primary discharge diagnosis in...

Error Bounds for Physics Informed Neural Networks in Generalized KdV Equations Placed on Unbounded Domains

In this paper we study a rigorous setting for the numerical approximation via deep neural networks of the generalized Korteweg-de Vries (gKdV) model in one dimension, for subcritical and critical nonlinearities, and assuming that the domain is the unbounded real line. The fact th...