University of Birmingham

Promises and pitfalls of mRNA-based vaccines as cancer treatment

The success of mRNA-based COVID-19 vaccines has accelerated interest in applying mRNA technology to oncology. mRNA cancer vaccines offer the potential for precise, patient-specific treatment with reduced off-target effects and may become an important component of future cancer ca...

Stakeholder Integration, Ethical Orientation, and Environmental Performance: Evidence From SMEs in Ghana

ABSTRACT This paper offers a novel theoretical account of how and when stakeholder pressures translate into environmental performance. Building on the Natural Resource‐Based View, we develop a moderated‐mediation model showing (a) stakeholder integration mediates the effect of pr...

Optimization of thermal comfort in residential buildings: analysis of indoor thermal energy cycle in low-carbon green design

Abstract With the intensification of global climate change and energy crisis, people’s attention to thermal comfort and low-carbon design of building environment is increasing day by day. Indoor thermal comfort not only affects the health and quality of life of residents, but is...

Reporting of justifications for withholding established effective interventions in randomised placebo-controlled trials: a systematic review

Randomised-controlled-trials (RCTs) are crucial for assessing the efficacy of new treatments. Some RCTs are placebo-controlled, which is uncontroversial when there is no established effective intervention or when a placebo is added to one. However, withholding an established effe...