University Hospital Leipzig

From mother’s plate to newborn’s health: dietary patterns and pregnancy outcomes—a cohort study

Abstract Background Maternal nutrition during pregnancy significantly influences both maternal and neonatal health outcomes, yet distinct dietary patterns and their impacts remain underexplored. The objective of this study was to identify dietary patterns during pregnancy and to...

Growth parameters and IGF-1 axis biomarkers differ among omnivorous, vegetarian, and vegan children

Abstract Purpose Whereas an increasing number of families choose a vegan or a vegetarian diet, the effects of a plant-based nutrition on height and BMI of children and their IGF-1- and IGFBP-3-serum concentrations as measures for growth and development are not entirely described....

Variation in meningioma recurrence risk estimates across observational cohorts: the influence of calendar time, WHO classifications, geographical settings, and healthcare systems

Abstract Purpose Recurrence risk estimates underpin meningioma research, including molecular classification and clinical trial benchmarking, yet are often based on retrospective or historical data. The aim of this study was to assess the variation of recurrence risk estimates acr...

Post-COVID-19 Condition has High Prevalence in Patients with Immune-mediated Inflammatory Diseases and Negatively Impacts Quality of Life

Abstract Introduction: Pandemic situation by severe acute respiratory syndrome coronavirus 2 and the associated disease (coronavirus disease 2019 [COVID-19]) presents broad challenges. Post-COVID-19 condition represents a continuum of persistent symptoms following the acute cours...

Accelerating Translation of NK Cell Therapies to the Clinic: A European Perspective

Adoptive immunotherapies have emerged as a promising strategy in the treatment of hematological malignancies. To date, seven chimeric antigen receptor (CAR)-T cell products have obtained market authorization in Europe for B-cell malignancies, where they have revolutionized treatm...

Real-world data on patient-reported outcomes and potential factors associated with pain after thyroid/parathyroid surgery: a prospective QUIPS registry analysis of a large cohort – sparking new pain management concepts

Abstract Background Although thyroid and parathyroid surgeries are common elective procedures in Germany, postoperative pain management remains unstandardized. This prospective study sought to quantify postoperative pain intensity after thyroid and parathyroid surgery and to exam...