University Hospital Centre Zagreb

Delayed normalization of tissue transglutaminase antibodies in children with celiac disease and type 1 diabetes mellitus

OBJECTIVES: Diabetes mellitus type 1 (T1DM1) and celiac disease (CD) can coexist in a patient. The aim was to evaluate the characteristics of children with both CD and T1DM and children with CD alone and to compare normalization rates of tissue transglutaminase immunoglobulin A c...

Brain MRI Features of Human Neuroinvasive Usutu Virus Infections

Background/Objectives: Neuroradiological features of neuroinvasive Usutu virus (USUV) infection are poorly understood, as current knowledge is largely limited to case reports. This study aimed to describe brain MRI patterns, and assess disease severity and vital and functional ou...

Immunohistochemistry for c-MET, HLA class II, and CD68 does not show prognostic value in early-stage classic Hodgkin lymphoma patients in the EORTC-GELA H9 intergroup randomised trial

Background In classic Hodgkin lymphoma (cHL), identifying high-risk patients is crucial for tailored treatment. Clinical risk factors are useful, but there is room for improvement. Although many diagnostic tissue-based biomarkers have been described to correlate with prognosis, n...

Biventricular vs conduction system pacing after atrioventricular node ablation for heart failure with atrial fibrillation: the CONDUCT-AF trial.

BACKGROUND AND AIMS: Randomized evidence comparing conduction system pacing (CSP) and biventricular pacing (BVP) following atrioventricular node ablation in patients with refractory atrial fibrillation (AF) and heart failure (HF) remains limited. This study evaluated whether CSP...

Evaluation of Services of a Multidisciplinary Team for Supportive and Palliative Care for Persons with Advanced Cancer at the Tertiary Hospital in Croatia over First Three years: A Retrospective Study

BACKGROUND: Supportive and palliative care, delivered by a multidisciplinary team, plays a crucial role in improving the quality of life for people with advanced cancer by addressing physical, psychological, and social needs. There are no published data evaluating the work of suc...

Cloud Noticing and Forest-Therapy Elements in a Coastal Resort: An Exploratory Randomised Field Study

Wellness resorts often market natural scenery without knowing whether a structured way of attending to it changes guests’ immediate experience. We examined cloud noticing and forest-therapy elements as two low-infrastructure forms of nature-directed hospitality programming. This...

The SISAQOL-IMI glossary: harmonising terminology for patient-reported outcomes in cancer clinical trials

Abstract Background This study presents the development of a glossary designed to harmonize terminology, foster consensus and support the successful implementation of the Setting International Standards in Analysing Patient-Reported Outcomes and Quality of Life Endpoints in Cance...

I Want to Live More : Self-Talk Under the Pressure of Breast Cancer

In this study, self-talk is conceptualized as a self-regulatory intrapersonal communication process that integrates emotional, cognitive, and social dimensions. Unlike prior studies that focus on the frequency or valence of self-talk, as well as the effectiveness of psychoeducati...

Contemporary Landscape of Active Clinical Trials in Pancreatic Ductal Adenocarcinoma: A ClinicalTrials.gov–Based Narrative Review with a Scoping Approach

Background: Pancreatic adenocarcinoma (PDAC) remains one of the most lethal malignancies, with limited survival gains despite advances in systemic therapy. However, rapid expansion of biomarker-directed therapies, immunotherapy, and novel treatment modalities has created an incre...

European S2k guidelines for hidradenitis suppurativa/acne inversa Part 1. Epidemiology, diagnosis and clinical assessment

BACKGROUND: This first part of the S2k guidelines is an update of the 2015 S1 European guidelines based on the structured assessment of clinically relevant topics by the panel of experts. It is complemented by Part 2, which deals with treatments. OBJECTIVES: These guidelines aim...

Superficial Temporal Artery Access for Angiography in a Patient With Leriche Syndrome, Subclavian Artery Occlusions, Multiple Acute Arterial Thromboses, and Heart Failure

Despite significant progress in revascularization techniques, the vascular approach itself can still be a challenge in complex polyvascular disease. In this case report, we describe the feasibility of a potentially underutilized alternative vascular approach in a patient with mul...

3D-printed cranioplasty molds – a technical note on lessons learned and things to avoid

Abstract 3D cranioplasty for cranial defects is growing ever more prevalent. As the technology becomes more accessible, the number of professionals being introduced to it is constantly on the rise. Herein we share our experience with 3D cranioplasty, point out the pitfalls and th...

Course of Portal Hypertension and Its Prognostic Impact After Liver Transplantation

ABSTRACT Background While portal hypertension (PH) typically resolves after liver transplantation (LT), persistence of PH may affect post‐transplant outcomes. We assessed the evolution of PH after LT and its impact on adverse outcomes. Methods We recorded clinical, laboratory, an...

Usefulness of Automated Hematology System Sysmex XN‐3100 for the Quantification of Schistocytes and Early Detection of the Underlying Thrombotic Microangiopathy

ABSTRACT Introduction Light microscopy is still the gold standard method for schistocyte counting in the blood smear. Some hematology analyzers can quantitatively determine fragmented red blood cells (FRC) as part of the full blood count. We examined the usefulness of two quantit...

The Use of Extracorporeal Organ Support Therapies for Acute Kidney Injury in Cancer Patients

Acute kidney injury (AKI) is a frequent and serious complication in patients with cancer, associated not only with increased morbidity and mortality, but also with the interruption or modification of anticancer therapy. In critically ill patients with cancer, AKI arises from a co...