Université Toulouse III - Paul Sabatier

Perinatal exposure to nano-polystyrene: deleterious imprinting on inflammatory bowel diseases

The extent of production and use of plastics leads to release of nanoplastics (NPL) into the environment, where they undergo weathering that could alter their toxicological properties. NPL enter the human food chain via contaminated food, and food packaging, and within the body t...

Androgen receptor imprints satellite cell stemness and preserves their reservoir for lifelong regeneration and optimal repair

Skeletal muscle stem cells (MuSC) are the guardians of muscle regeneration, sustaining tissue integrity through a delicate balance of quiescence, activation, and lineage commitment. While numerous molecular cues have been implicated in regulating these processes, the influence of...

Ground states on a fractured strip and one-dimensional reduction

We consider the nonlinear Schrödinger equation on a strip with Neumann boundary conditions and a delta condition at x = 0 . We first show the existence of ground states as minimizers of the action or of the energy under suitable constraints. We then prove that the energy minimize...

Revealing archaeological olive diversity: insights from stone geometric morphometrics, experimental charring, and varietal identification (Port-la-Nautique, France, Roman period)

The cultivated olive tree, domesticated in the Levant by the mid-5th millennium BCE, spread westward across the Mediterranean to reach southern France by 600 BCE. Although geometric morphometrics applied to archaeological olive stones has provided insights into this diffusion, mo...

Association of plasma growth differentiation factor-15 with the frailty phenotype – Evidence from the COGFRAIL study

Background Growth differentiation factor-15 (GDF-15) has been consistently associated with physical frailty. However, it remains unclear whether GDF-15 further discriminates adverse outcomes among older adults who are already physically and cognitively impaired. Objectives To eva...

Stereoselective trans -1,4 Polymerization of Isoprene and β -Myrcene Mediated by Iron Complexes Bearing 1,1-Diaryl- N -(quinolin-8-yl)methanimine Ligands

Abstract Although iron has emerged as an earth-abundant alternative for 1,3-diene coordinative polymerization, stereoselective iron systems remain uncommon and are often associated with limited catalytic activity. Here, we report three iron(II) complexes supported by 1,1-diaryl-N...

NucGen3D: A synthetic framework for large-scale 3D nuclear segmentation with open-source training data and models

A bstract Robust nuclear segmentation in 3D microscopy images is a critical yet unresolved challenge in quantitative cell biology, hindered by the scarcity and variability of annotated volumetric datasets. Because such data are difficult to obtain, most state-of-the-art approache...

Zoological biobanks as a resource for microplastic analysis: a Py-GC-MS/MS case study on sea cucumbers

Microplastics have spread through every ecosystem studied. Yet, documenting their spatiotemporal distribution remains challenging, particularly in marine environments where sampling is costly and difficult. Archived specimens in zoological biobanks offer an underused resource for...

Leveraging human-trained neural networks for cross-species chromatin regulation annotations

Abstract Analogous to the Encyclopedia of DNA Elements (ENCODE) project, the Functional Annotation of ANimal Genomes (FAANG) consortium has produced chromatin annotations for domesticated animals, albeit in smaller amounts. Although acquiring experimental data is more accessible...

Refinements on higher order Weil–Oesterlé bounds via a Serre type argument

Abstract Weil's theorem gives the most standard bound on the maximum number of points of a curve of genus over a finite field . This bound was improved by Ihara and Oesterlé for larger genus. A recent point of view allows one to recover these bounds by solving a sequence of semi‐...

Formal moduli problems and derived Lie algebras

We show that derived Lie algebras and restricted Lie algebras classify formal moduli problems on Artin divided power algebras and truncated algebras respectively. This article is part of the theme issue 'Derived Lie algebras in geometry and topology'.

Convergence Rates for Polynomial Optimization on Set Products

Abstract. We consider polynomial optimization problems on Cartesian products of basic compact semialgebraic sets. The solution of such problems can be approximated as closely as desired by hierarchies of semidefinite programming relaxations, based on classical sums of squares cer...

A Survey on Clustered Federated Learning: Taxonomy, Analysis and Applications

As Federated Learning (FL) expands, the challenge of non-independent and identically distributed (non-IID) data becomes critical. Clustered Federated Learning (CFL) addresses this by training multiple specialized models, each representing a group of clients with similar data dist...

Characterization of tensile and torsional fatigue behaviors of additively manufactured super duplex stainless steel SAF 2507

Abstract Super duplex stainless steels (SDSSs) are well known for their good mechanical properties and corrosion resistance inherited from the dual-phase microstructure with equivalent proportion of ferrite and austenite. The development of additive manufacturing has given rise t...

Effect of the WHO ICOPE prevention program on falls and mobility functions : a retrospective study in France

Abstract Background World Health Organization developed the Integrated Care for Older People (ICOPE) prevention program in order to promote the maintenance of intrinsic capacities for older adults, based on six key domains. Each key domain is a risk factor for falls in older adul...