Université de Tours

Combined prognostic value of age at onset and socioeconomic status for long-term survival in metastatic breast cancer

We investigated the combined long-term prognostic value of age at onset and socioeconomic status (SES) on breast cancer overall survival (OS) and metastasis-free survival (MFS) in a cohort of women with metastatic breast cancer. Age at onset was defined as the age at primary diag...

Describing the emotional change experienced by patients with chronic somatic diseases who took part in a supportive program with complementary therapies: a qualitative study

Quantitative studies have suggested that complementary therapies (including mind-body and art therapies) are relevant to support patients with chronic somatic diseases. The “Health Promotion Education” department of Nantes University Hospital created in 2012 an association entitl...

Simulation of the Rotational Molding Process of Polyethylene Using the Smoothed Particle Hydrodynamics Method

ABSTRACT This work presents the development of a numerical model based on the smoothed particle hydrodynamics (SPH) method to simulate the rotational molding process of powder thermoplastic polymers, used in the manufacture of liners for high‐pressure hydrogen tanks. Rotational m...

Evaluation of Disease Severity Using CSF Biomarkers in Patients With Probable Cerebral Amyloid Angiopathy

Cerebral amyloid angiopathy (CAA) is currently diagnosed using MRI-based Boston criteria. However, imaging markers represent downstream consequences of vascular injury and may not fully reflect disease severity. CSF biomarkers, particularly β-amyloid 1–42 (Aβ42) and β-amyloid 1–4...

Towards a deep-learning genomic tool for risk stratification and diagnostic support in sporadic ALS

Abstract Background A variety of common and rare genetic factors have been implicated in the development of amyotrophic lateral sclerosis (ALS), and the evidence is that a genetic component is present in most affected individuals. However, our current understanding of ALS genetic...

Psychological capital and gender: entrepreneurial orientation

Purpose This study examines the associations of psychological capital (PsyCap) and gender with entrepreneurial orientation (EO) among Ecuadorian entrepreneurs, providing evidence from an underexplored Latin American context. Design/methodology/approach Survey data were collected...

A Survey on Clustered Federated Learning: Taxonomy, Analysis and Applications

As Federated Learning (FL) expands, the challenge of non-independent and identically distributed (non-IID) data becomes critical. Clustered Federated Learning (CFL) addresses this by training multiple specialized models, each representing a group of clients with similar data dist...

Unraveling HBV Life Cycle by Fluorescent Microscopy Imaging

The hepatitis B virus (HBV) is a worldwide hepatotropic virus despite the availability of a highly effective vaccine. Currently, the most efficacious treatment against HBV infection is the use of interferon and nucleos(t)ide analogs, which effectively suppress viral replication b...

Exposure to workplace and domestic violence as differential risk factors for stress and depression

Exposure to interpersonal violence is a well-established determinant of poor mental health. However, violence often occurs across multiple life domains rather than in isolation, and its psychological consequences may differ depending on the context and outcome considered. This st...

Comparison of Materno-Neonatal Outcomes Between Cook Balloon and Prostaglandin Methods in Labor Induction Among Pregnancies Complicated by Fetal Growth Restriction: A Retrospective Cohort Study from France

Background: To evaluate whether the methods of induction of labor (IOL) used for pregnancies complicated with fetal growth restriction (FGR) have different impacts on materno-fetal outcomes. Methods: This was a single-center, retrospective cohort study conducted over a one-year p...

On the effects of using nonlinear springs in mono-coupled periodic structures

Abstract Many strategies are employed to control structural vibration. One of them is to design structural elements in a periodic arrangement to obtain the so-called bandgap effect. For infinite periodic structures, bandgaps are defined as frequency ranges where waves do not prop...

Queen loss fails to elicit physiological and transcriptional responses in workers of the invasive garden ant Lasius neglectus.

Colonies of insects with morphologically distinct castes have been called superorganisms because the function of their queens and workers is analogous to the germline and soma in metazoan bodies. In the case of formicoid ants, workers typically have lost the sperm storage organ,...