Université de Lille

The interplay of time pressure and AI assistance reveals moral responsibility recalibration in high-stakes decisions

As artificial intelligence (AI) systems are increasingly integrated into high-stakes decision-making environments, understanding how humans interact with these systems under time pressure is critical for ethical and effective human-AI teaming. While previous research has shown th...

Synthesis of functional unknown input observers for MIMO systems with arbitrary relative degree

This paper addresses the design of functional unknown input observers for multi-input multi-output linear time-invariant systems. In contrast to many existing approaches, the proposed method is applicable to systems with arbitrary relative degree, which significantly enlarges the...

The Relationship Between Physical Fitness and Physical Literacy: Empirical Evidence Linking Two Physical Activity-Health Concepts

Research on promoting physical activity (PA) primarily revolves around two key concepts: physical fitness (PF), defined as a set of measurable physical capacities (strength, speed, endurance and coordination), and physical literacy (PL), a multidimensional construct encompassing...

Looking back over 20 years of research into ‘parkour and urban space’

Parkour is a lifestyle sport that originated in the Parisian suburbs in the 1990s. It has sparked research in various fields, with studies examining either the activity itself or using it as a stage to discuss broader or relatively distinct topics. As no systematic review of the...

Daratumumab, lenalidomide, and dexamethasone in transplant-ineligible newly diagnosed multiple myeloma: MAIA final survival analysis

Abstract In previous analyses of MAIA, daratumumab plus lenalidomide/dexamethasone (D-Rd) significantly improved progression-free survival and overall survival (OS) versus lenalidomide/dexamethasone (Rd) in transplant-ineligible newly diagnosed multiple myeloma (NDMM). We report...

Configurational Approaches to Optimal Distinctiveness: Exploring Signal Sets and Originality for Entrepreneurship Legitimacy

For entrepreneurs, the legitimisation process in the early stages is crucial for acquiring essential resources and ensuring the viability and growth of their new ventures. Drawing on signalling theory and optimal distinctiveness literature, the article investigates the configurat...

Identification of living (Rose Bengal)-stained benthic foraminifera using automated image recognition

Abstract. Living and fossil benthic foraminifera are widely used as bioindicators of ecosystem quality, but their analysis is time-consuming. With the help of artificial intelligence, models for the automatic identification of fossil planktonic foraminifera and, more recently, be...

PLCG2 downregulation impairs synaptic function and increases Alzheimer’s disease hallmarks in neuronal cultures

We developed a high-content screening to investigate how Alzheimer’s disease (AD) genetic risk factors may affect synaptic mechanisms in rat primary neuronal cultures. Of the target genes identified, we found that Plcg2 downregulation in mouse dentate gyrus neurons consistently d...

Homicide at home: setting the agenda for an international collaboration to improve support for children bereaved due to family violence

Background: Bereavement due to fatal family violence (e.g. intimate partner homicide, filicide, parricide, siblicide) is a profoundly disruptive experience for children, with lifelong psychosocial consequences. Although the need for fatal family violence prevention is increasingl...

Visible-Light-DrivenPorphyrin/ZnO Nanohybrids forUltrasensitive Room-Temperature Triethylamine Sensing

Abstract Real-time monitoring of toxic triethylamine (TEA) at room temperature remains a significant challenge for metal oxide chemiresistors due to their typically high-power consumption and thermal requirements. This work presents a highly responsive, visible-light-activated ga...

Data-driven mapping of known and novel fluid biomarker progression profiles in genetic frontotemporal lobar degeneration

Abstract Introduction Recent proteomic studies have identified both established and novel proteins in genetic frontotemporal lobar degeneration (FTLD). However, it remains unclear at what point in the disease these proteins deviate from normal levels and how their trajectories re...

Adrenaline Use and Request for Emergency Medical Assistance to Manage Food Anaphylaxis

Summary Adrenaline was rarely used, medical assistance being requested in two thirds of anaphylaxis cases. Medical assistance request was less frequent if milder or no cardiovascular anaphylaxis symptoms.

Coordinative chain transfer homopolymerization and copolymerization of bio‐sourced β ‐myrcene and butadiene promoted by iminopyridine iron complexes

Abstract A family of iron complexes bearing iminopyridine (ImPy) ligands with systematic variations on the N ‐aryl and pyridine moieties was evaluated as pre‐catalysts for the coordinative polymerization of β‐myrcene and butadiene. Upon activation with Al i Bu 3 and trityl borate...

Visible mould and blood inflammatory phenotypes of asthma in adults: the CONSTANCES cohort

Studying the associations between indoor mould contamination and blood inflammatory phenotypes may provide further insight into the mechanisms by which this environmental factor affects asthma. Among 1870 adults with current asthma from a population-based cohort, 29.6% reported v...

A Phenomenological Framework for Structured Light in the Claro-Torsion Metric Cosmology: Toward the NovaFusion Experimental Approach

This manuscript develops a revised phenomenological formulation of the Claro-Torsion Metric (CTM) cosmology, with a particular emphasis on structured light as a physically meaningful carrier of topology, polarization, phase, and information. The model is reformulated with explici...

Conformal principal-asymptotic nets: Parametric design and modular construction of elastic gridshells

Current modular design approaches often rely on numerical optimization to satisfy fabrication constraints, which can be computationally intensive and sensitive to initial geometric conditions. This work introduces a parametric design algorithm based on Conformal Principal-Asympto...

Identification of Activity, Insulin, and Dietary Thresholds Associated With Exercise‐Related Hypoglycaemia and Hyperglycaemia in Children With Type 1 Diabetes: A Free‐Living Study Using Explainable Machine Learning

ABSTRACT Aims Some studies have explored associations between physical activity (PA) and hypoglycaemia in real‐life in type 1 diabetes (T1D) but without fully accounting for two major confounders, diet and insulin. We aimed to identify thresholds of PA characteristics, insulin, a...

FGFR3-driven gene regulatory network analysis reveals a protumoral role for p63 in luminal bladder tumors

Fibroblast growth factor receptor 3 ( FGFR3 ) is one of the most frequently altered genes in bladder cancer, primarily through activating mutations that drive oncogenesis and are enriched in luminal tumors. However, the underlying gene regulatory network (GRN) remains poorly char...