Université de Bordeaux

LDL Cholesterol Lowering With Evolocumab Before Percutaneous Coronary Intervention for Acute Myocardial Infarction

Importance: Proprotein convertase subtilisin-kexin type 9 (PCSK9) inhibition is recommended as second- or third-line lipid-lowering therapy after myocardial infarction (MI), resulting in prolonged periods of inadequate low-density lipoprotein cholesterol (LDL-C) control. Whether...

Grassland destruction causes shifts in plant traits that persist during recovery

Old-growth grasslands assemble over millennia and support high biodiversity and many ecosystem services, but continue to undergo widespread destruction for production of crops, timber, and minerals. How biodiversity recovers after grassland destruction and the functional conseque...

Polyphenol-Rich Opuntia ficus-indica Cladodes: An Integrated Metabolomic, In Vivo and In Silico Study Supporting Their Hypolipidemic and Hepatoprotective Effects

Background: Hyperlipidemia is a major risk factor for cardiometabolic disorders, including non-alcoholic fatty liver disease (NAFLD), and is closely associated with oxidative stress. Opuntia ficus-indica (OFI) cladodes are recognized as a rich source of bioactive phytochemicals;...

Titanium‐Catalyzed Defluorination of Poly(Vinyl Fluoride) and Poly(Vinylidene Fluoride) Under Friedel–Crafts Conditions

ABSTRACT The defluorination of poly(vinyl fluoride) (PVF) and poly(vinylidene fluoride) (PVDF) fluoropolymers catalyzed by titanium species in the presence of triethylsilane (Et 3 SiH) and aromatic solvents is reported. Commercially available Ti complexes (e.g., [Cp 2 TiCl 2 ] (...

Titanium‐Catalyzed Defluorination of Poly(Vinyl Fluoride) and Poly(Vinylidene Fluoride) Under Friedel–Crafts Conditions

ABSTRACT The defluorination of poly(vinyl fluoride) (PVF) and poly(vinylidene fluoride) (PVDF) fluoropolymers catalyzed by titanium species in the presence of triethylsilane (Et 3 SiH) and aromatic solvents is reported. Commercially available Ti complexes (e.g., [Cp 2 TiCl 2 ] (...

Relationships between general practice residents’ level of reflection and their competencies development: results from a pilot cross-sectional study

Reflective practice is a cornerstone for developing professional competence. Despite its importance, the relationship between levels of reflection and competence remains underexplored in medical education. This association was described in trainee teachers. Along with initiating...

Elucidating anisotropic seed-mediated nanorod growth in solution

International audience

Polymer-Driven Self-Templated Synthesis of Boronate-COF Hollow Spheres: Toward the Development of Size-Selective Nanoreactors

Abstract Covalent organic frameworks are a family of porous crystalline structures gaining attention due to their promising applications. However, despite significant efforts, the synthesis and understanding of uniform and specific morphologies remain a challenge. Herein, we repo...

Predicting driving performance from resting-state EEG using explainable gradient boosting

Abstract Sleep deprivation substantially impairs driving performance, underscoring the need for Electroencephalography (EEG)-derived markers associated with driving-performance vulnerability under varying levels of sleepiness. In this study, resting-state EEG signals were recorde...

Efficacy of rTMS in Post‐Stroke Bilingual Aphasia: A Single Case Experimental Design

BACKGROUND: The application of non-invasive brain stimulation in the rehabilitation of bilingual individuals with aphasia following a stroke is understudied. Recent studies show benefits of anodal cerebellar transcranial Direct Current Stimulation in bilinguals, while in monoling...

Access and excess as interacting drivers of antimicrobial resistance in low and middle income countries

Antimicrobial resistance (AMR) disproportionately affects low- and middle-income countries (LMICs). However, dominant stewardship frameworks often emphasize overuse, underrecognizing the access–excess dynamic: inadequate access to effective antimicrobials coexisting with inapprop...

Topological robustness of optical skyrmions through a real-world free-space link

Structured light offers a promising solution for the increasing data demands of modern optical networks, opening up degrees of freedom that can be leveraged for greater channel capacity and more bits per photon. However, its implementation is hindered by real-world distortions, f...

PLCG2 downregulation impairs synaptic function and increases Alzheimer’s disease hallmarks in neuronal cultures

We developed a high-content screening to investigate how Alzheimer’s disease (AD) genetic risk factors may affect synaptic mechanisms in rat primary neuronal cultures. Of the target genes identified, we found that Plcg2 downregulation in mouse dentate gyrus neurons consistently d...

Robot-Assisted Versus Open and Laparoscopic Radical Nephrectomy with Inferior Vena Cava Thrombectomy forRenal Cell Carcinoma: A Systematic Review and Meta-Analysis

Background/Objectives: To compare perioperative, pathological, functional, and oncological outcomes of robot-assisted radical nephrectomy with inferior vena cava tumor thrombectomy (RARN-TT) versus open (ORN-TT) and laparoscopic (LRN-TT) approaches. Methods: PubMed, Scopus, and W...

Measuring Ocean Surface Waves

Abstract Propagating waves on the ocean surface can be represented as a stochastic process whose statistics are characterized by a spectrum. This paper reviews methods for measuring the wave spectrum and related quantities. Observations begin by sensing fluid dynamical properties...

A ComplexSpin-Transition Thermal Hysteresis Unlockedby Two Competing Symmetry-Breakings

Abstract The spin-crossover material [Fe(NH2trz)3](NO3)2 belongs to the class of 1D triazole-based polymeric SCO complexes. It exhibits a thermal phase transition, with a 28 K wide thermal hysteresis, characterized by phase transition temperatures T↑ = 346 K upon warming and T↓ =...

Adherence to Biologics and Psycho-cognitive Factors in Axial Spondyloarthritis: A Multicentric Cross-sectional Study

Background/Objective: Adherence to treatment in axial spondyloarthritis (axSpA) remains poorly documented, with estimates ranging from 28.2% to 70.6%. Psychological factors may influence adherence. This study aimed to assess adherence to biological disease-modifying antirheumatic...

Structure andRheology of DPPC–CholesterolMonolayers

Abstract Lipids are key components of biological interfaces and are constantly subjected to external stress and shear flow. In this work, we focus on DPPC–cholesterol monolayers at water–air interfaces and study their response to compression and shear. The choice of lipids is mot...

Cuprous Ions Binding to Cytosine and Guanine Oligonucleotides

Using a set of spectroscopic experiments, we investigated the binding of Cu 2+ and Cu + to a comprehensive series of nucleic acid‐related molecules, ranging from individual nucleobases to oligonucleotides up to six nucleotides in length. We demonstrate the selective binding of Cu...

Bioelectrical Impedance in Cardiovascular Health

Bioelectrical impedance (BI) is gaining significant attention for its potential in cardiovascular health monitoring and early disease detection. On the basis of the principles of tissue conductivity and body composition, BI operates by applying a low-amplitude alternating current...