Institution
Universidade Federal de Minas Gerais
Recent research
- Climate & EnvironmentOpen access
Abstract Urban freshwater ecosystems are increasingly exposed to mixtures of pollutants, including per- and polyfluoroalkyl substances (PFAS). However, their ecological effects remain poorly understood, especially in tropical regions with limited sanitation infrastructure. This s...
- Health & MedicineOpen access
Metastatic progression in melanoma is driven by the coordinated activity of adhesion molecules and growth factor receptors, yet the functional interplay between integrins and VEGFR-related signaling remains poorly defined. This study investigated the role of α4β1 integrin, also k...
- Climate & EnvironmentOpen access
Abstract Species of the genus Senga comprise a group of bothriocephalidean cestodes that predominantly parasitize freshwater teleost fishes, causing severe histopathological alterations due to scolex attachment to the digestive tract or obstruction of the intestinal lumen. The Si...
- BiologyOpen access
Microbial oil production by Yarrowia lipolytica strains using glycerol as carbon source
Abstract Yeasts can produce microbial oil from hydrophobic substrates such as glycerol, a byproduct of the biodiesel industry that is often undervalued in the market. Yarrowia lipolytica is capable of degrading glycerol and is considered a model organism for studying lipid accumu...
- Health & Medicine
Background: Meningiomas are the most common primary intracranial tumors, often requiring complex management due to their proximity to critical neurovascular and orbital structures. While surgery remains the cornerstone of treatment, achieving optimal outcomes requires coordinated...
- Health & MedicineOpen access
This study investigated the influence of organic solvents on the depth of cure (DOC) of resin composites. Two conventional (Filtek Universal [FU] and Beautifil II [BE]) and two bulk-fill (Filtek One Bulk Fill [FO] and Beautifil-Bulk [BB]) composites were evaluated. Cylindrical sp...
- BiologyOpen access
Targeted therapies have substantially advanced cancer treatment; however, therapeutic resistance remains a major challenge, particularly in lung cancer. Polo-like kinase 1 (PLK-1), a key regulator of mitosis, is frequently overexpressed in lung tumors and has emerged as an attrac...
- Health & MedicineOpen access
Abstract Chagas disease, caused by the Trypanosoma cruzi, remains a major global health burden with limited prophylactic options. We describe a vaccine platform that leverages a peptide epitope derived from the T. cruzi trans-sialidase group II (Tc85pep), displayed on the virus-l...
- Society & EconomicsOpen access
Abstract In this study, we propose a new exact approach to the competitive facility location problem with a limited choice rule. The problem consists in locating facilities to capture a market share that maximizes the profits of a new company entering into a competitive marketpla...
- Health & MedicineOpen access
Abstract Traumatic brain injury (TBI) remains a major cause of neurological morbidity worldwide, and mild TBI (mTBI) is frequently associated with emotional disturbances, including anxiety-like behavior. Although classical mechanisms of secondary injury have been extensively char...
- Society & Economics
Disciplinary literacy in high school CLIL Mathematics: a CEFR descriptor-based study
Abstract This study investigates the extent to which the Common European Framework of Reference for Languages (CEFR)-linked descriptors are transferable to mathematical and disciplinary literacy in Mathematics through Content and Language Integrated Learning (CLIL). It was conduc...
- Health & MedicineOpen access
Optimizing mini nutritional assessment as a prognostic tool in oncology: evidence from 50 hospitals
Objectives Diagnosing malnutrition in older individuals with excess weight is challenging, as commonly used tools rely on anthropometric measures such as body mass index (BMI) and calf circumference (CC), which can be affected by excess weight. To partially address this concern,...
- Biology
The emergence of Escherichia coli sequence type (ST131), especially its H30Rx subclade, has reshaped the epidemiology of urinary tract infections (UTIs) by combining multidrug resistance (MDR), extended-spectrum β-lactamase (ESBL) production, and biofilm formation. Clinical E. co...
- Health & MedicineOpen access
BACKGROUND: The management of decompensated autoimmune hepatitis (AIH) cirrhosis is one of the most challenging and controversial scenarios in hepatology. Clinicians face a high-stakes dilemma: whether to initiate immunosuppression to halt inflammatory activity or prioritize live...
- BiologyOpen access
This repository contains all scripts (Bash, Python and R), processed datasets, intermediate files and supplementary material used in the analyses described in the accompanying manuscript.
- BiologyOpen access
This repository contains all scripts (Bash, Python and R), processed datasets, intermediate files and supplementary material used in the analyses described in the accompanying manuscript.