Universidade Estadual de Campinas (UNICAMP)

Barriers and drivers of industry 4.0 adoption: insights from a bibliometric analysis

Purpose This study aims to map the intellectual landscape of research on the barriers and drivers influencing Industry 4.0 (I4.0) adoption. By combining bibliometric and systematic review methods, it identifies the main contributors, research clusters and thematic trends shaping...

Diffusion Tensor Imaging as a Preliminary Study of White Matter Associations with Surgical Outcome in Mesial Temporal Lobe Epilepsy

Objective This study evaluates pre-surgery white matter abnormalities in evaluating the association between pre-surgical white matter integrity and post-surgery outcomes at the group level using Diffusion Tensor Imaging (DTI) in patients with Mesial Temporal Lobe Epilepsy (MTLE),...

Predicting the continuity of international scientific collaboration in the BRICS: a machine learning approach

Purpose This study aims to predict respondent-reported continuity of international scientific collaboration within the BRICS through a supervised binary classification approach. It examines whether respondents reported that collaborations continued in the form of joint projects a...

Effect of a sodium fluoride rinse on the composition of early oral biofilms formed in situ on enamel and dentine

OBJECTIVES: Dental caries results from dysbiotic shifts in the microbial community, so modulating biofilm composition represents a valid preventive strategy. The aim of this double-blind randomized crossover in situ study was to investigate how a fluoride rinse can modify the com...

Pattern-Anchored Diagnosis of Oral Epithelial Dysplasia: A Position Paper From COST Action INTERCEPTOR Working Group 2

Abstract Purpose Oral epithelial dysplasia (OED) is the principal histopathological marker for malignant risk stratification in oral potentially malignant disorders (OPMDs). Current World Health Organisation (WHO) three-tier and other binary grading systems are limited by modest...

Rate-dependent mechanical–electrical–thermal abuse response of fresh and aged tabless 4695 cylindrical cells under radial indentation

Electrochemical aging can alter the mechanical abuse response of large-format cylindrical cells, but its effect under dynamic loading remains insufficiently resolved. This study compares fresh and aged tabless 4695 cells at 100 % State of Charge (SoC) under dynamic radial indenta...

Structurally conditioned autonomy and assisted dying: health equity, vulnerability, and end-of-life decision-making

Assisted dying is frequently justified through appeals to individual autonomy and self-determination. However, contemporary end-of-life decision-making occurs within broader social, economic, and institutional conditions that may significantly shape experiences of suffering and t...

Functional mapping and engineering of the Sec translocon unlocked by a cell-free system

Abstract Almost all proteins are inserted or translocated across membranes by the universally conserved Sec translocon. Despite its central role, experimental access to Sec function has remained limited. Here, we present a cell-free protein synthesis platform that inserts SecYEG...

The Effects of the Fire–Grazing Sequence in Mediterranean Soil Ecosystems: A Scoping Review

Abstract Mediterranean ecosystems are increasingly affected by the rising frequency and intensity of wildfires, requiring proactive management strategies such as grazing or prescribed burns to control post-fire biomass. Despite an extensive body of literature addressing the indiv...

High-productivity PBF-LB/M processing of Ti–Nb–Ta alloys: tailoring microstructure and phase evolution for low-modulus orthopedic implants

Abstract Metallic bone implants with a high Young’s modulus can cause stress shielding, leading to bone resorption and long-term failure. β-stabilized titanium alloys have been widely explored to overcome this limitation due to their lower elastic stiffness. In this study, Ti-20N...

New Approaches for Monitoring Edible Coating Quality Using Hyperspectral Imaging (HSI) and Chemometrics

Abstract Preserving fruit quality after harvest presents a major challenge for the food industry, and edible coatings are increasingly proposed as sustainable alternatives to synthetic packaging materials. This work offers a concise review of recent advances in edible coatings fo...

Hypothalamic neurovascular and extracellular matrix remodeling: Cellular niche orchestration of immune-metabolic adaptation to nutritional stress

Abstract Under normal physiological conditions, hypothalamic resident immune cells interact with neurons and other non-neuronal cells to maintain tissue homeostasis. Accumulated evidence from studies with rodents shows that excessive intake of saturated fatty acids triggers hypot...

Hypokalemic Hypochloremic Metabolic Alkalosis in Cystic Fibrosis: A Retrospective Observational Study with Clinical Characterization, CFTR Genetic Profiling, and a Comparative Genetic Analysis with Patients from a Brazilian Reference Center

Cystic fibrosis is a genetic disorder caused by pathogenic variants in the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) gene and may be complicated by hypokalemic hypochloremic metabolic alkalosis (HHMA), resulting from excessive electrolyte loss through sweat. This...

Factors associated with discordance between the patient-reported Rheumatoid Arthritis Disease Activity Index (RADAI) and the Simplified Disease Activity Index (SDAI) concerning the achievement of treat-to-target goals – data from the REAL study

Abstract Background Treat-to-target (T2T) strategies in rheumatoid arthritis (RA) rely on regular assessment of disease activity using validated composite indices, with remission or low disease activity as therapeutic goals. The Simplified Disease Activity Index (SDAI) is widely...

A Surgical Algorithm for Upper Cervical Trauma Based on the AO Spine Upper Cervical Injury Classification System

Study Design. Global cross-sectional survey Objective. To establish a surgical algorithm for upper cervical spine injuries using the AO Spine Upper Cervical Injury Classification (UCIC) system, defining operative thresholds using a novel proposed Upper Cervical AO-Spine Injury Sc...

Matrix-dependent UVC/H2O2 degradation of pharmaceuticals in reverse osmosis concentrate

Abstract Reverse osmosis is widely applied as an advanced treatment technology due to its high efficiency in removing organic micropollutants from wastewater. However, this process inevitably produces a residue with a high contaminant load, posing environmental challenges and req...

Grassland destruction causes shifts in plant traits that persist during recovery

Old-growth grasslands assemble over millennia and support high biodiversity and many ecosystem services, but continue to undergo widespread destruction for production of crops, timber, and minerals. How biodiversity recovers after grassland destruction and the functional conseque...

Why grounded large language models fail without domain-specialized retrieval: an experimental scientometric study in solar physics

Abstract Recent applications of large language models (LLMs) in scientometric analysis often assume that the underlying evidence space is neutral and pre-given. We challenge this assumption empirically by demonstrating that retrieval infrastructure constitutes a methodologically...

Effects of organic solvents on the depth‐of‐cure determination of conventional and bulk‐fill resin composites

This study investigated the influence of organic solvents on the depth of cure (DOC) of resin composites. Two conventional (Filtek Universal [FU] and Beautifil II [BE]) and two bulk-fill (Filtek One Bulk Fill [FO] and Beautifil-Bulk [BB]) composites were evaluated. Cylindrical sp...

Programação visual para manufatura aditiva por extrusão monorosca: Parametrização do processo de deposição com base nas propriedades reológicas

A manufatura aditiva por extrusão de material tem sido investigada como rota para a fabricação de formas farmacêuticas personalizadas, nas quais dose, geometria e perfil de liberação podem ser ajustados às necessidades de diferentes pacientes. As abordagens predominantes empregam...