Universidade de Ribeirão Preto

Task force of the Brazilian Society of Otology and the Brazilian Academy of Neurotology: Menière’s Disease

Objective To critically review the available evidence on the pathophysiology and diagnosis of Menière’s disease and to provide consensus-based recommendations developed by a task force of the Brazilian Society of Otology and the Brazilian Academy of Neurotology. Methods A task fo...

Gender Effects of Party Switching on Mayoral Reelection: Evidence from Brazil

This paper investigates how party switching affects the reelection outcomes of Brazilian incumbent mayors from 2004 to 2016, with particular attention to gender-based heterogeneity. While most of the literature focuses on legislators, we examine the executive branch and assess wh...

Weaving a theory of change: mapping the pathway for Peer Support implementation in community mental health services in Brazil through co-produced participatory workshops

Abstract Background Peer Support (PS) has gained increasing recognition as a recovery-oriented practice in mental health services by valuing the experiential knowledge of individuals with lived experience of psychological distress. While PS has been widely implemented in high-inc...

EXPRESS: Dissociating attentional and working memory load in memory for emotional faces

There is evidence that both general attention load and face-specific working memory load modulate the processing of emotional faces, but the contribution of each remains uncertain. Here, we investigated how these resources modulate the recognition of emotional faces in working me...

Chelsea critical care physical assessment tool (CPAx) for adult patients hospitalized in the ward: measurement properties

Objective To evaluate the measurement properties of the Brazilian version of the Chelsea Critical Care Physical Assessment Tool (CPAx-Br) and evaluate the evidence of validity in adult general ward patients, extending its application beyond the critical care setting for which it...

Light stimuli attenuates inflammatory activation in primary bone marrow-derived macrophages

Abstract Bone repair depends on a regulated macrophage-driven inflammatory response. Non-activated macrophages (M0) differentiate into pro-inflammatory (M1) or anti-inflammatory (M2) phenotypes in response to microenvironmental signals. This study evaluated, in vitro, the effects...

Flow cytometry as a tool for assessing reactive oxygen species-related fluorescence in peripheral blood leukocytes from children and adolescents with asthma

Background Asthma is characterized by airway inflammation and bronchial hyperreactivity, with increased production of reactive oxygen species (ROS). Assessing oxidative stress is relevant to disease pathophysiology, but many methods have limitations in pediatric populations . Obj...

Built for bulk: posture, microanatomy and soft tissue shaped gigantism in Sauropoda

Abstract Sauropodomorph dinosaurs show how appendicular skeletal architecture accommodated extreme increases in body mass. Although sauropod gigantism has been linked to columnar limbs, wide-gauge posture, thick articular cartilage and tubular long-bone organization, the biomecha...

Characterization of an EPS-Enriched Emulsifying Extracellular Fraction Produced by a Brazilian Strain of Vreelandella zhaodongensis

Microbial exopolysaccharides (EPS) are structurally diverse biopolymers with ecological and biotechnological relevance due to their physicochemical and functional properties, including emulsification, metal chelation, and contributions to biofilm formation. In this study, an EPS-...

Fig. 5 in Acanthonyx petiverii " H. Milne Edwards 1834

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Autologous hematopoietic stem cell transplantation modulates epidermal-related inflammation/fibrosis mechanisms in systemic sclerosis patients

Abstract Background Autologous hematopoietic stem cell transplantation (auto-HSCT) has been shown to reduce cutaneous fibrosis and change dermal architecture in skin of systemic sclerosis (SSc) patients. However, its impact on the epidermis remains underexplored. Here, we examine...

Context-Dependent modulation of astrocytic Ca2+ signals by mitochondria: a computational study

Abstract Mitochondria regulate intracellular Ca 2+ by uptake through the mitochondrial Ca 2+ uniporter (MCU) and release via the mitochondrial permeability transition pore (mPTP). In astrocytes, neurotransmitter stimulation evokes Ca 2+ signaling, yet the role of mitochondria in...

Clostridium-based biorefineries in sugarcane bioethanol and biodiesel production: metabolic pathways, substrate diversity, and bioproduct yields

The global transition toward sustainable energy systems has intensified interest in biorefineries capable of converting renewable feedstocks and industrial residues into fuels and value-added chemicals. Bioethanol and biodiesel represent the two largest biofuel industries worldwi...

Computational Methods in Physical Virology: A Critical Perspective across lengths and timescales

Physical virology investigates viral particles by focusing on their assembly, stability, mechanics, and interactions with host cells, neutralizing antibodies, and surfaces. Within this field, computational virology is becoming an indispensable pillar, serving as a "computational...

How Alliances Build Innovation Capabilities but Narrow Their Redeployment in Amazonian Community‐Based Enterprises

ABSTRACT Research on strategic alliances often treats supplier capability development as an outcome, but rarely asks which capabilities are built or what they can be used for. We address this through an embedded single‐case study of a lead‐firm‐orchestrated network in the Brazili...

Reproducibility of the nordic musculoskeletal questionnaire in cardiac patients undergoing cardiovascular rehabilitation

Introduction Cardiovascular diseases are the leading cause of global mortality, while musculoskeletal comorbidities contribute to increased disability. Characterizing musculoskeletal limitations in cardiac patients undergoing cardiovascular rehabilitation is crucial for ensuring...

Is there an interaction between hypertension and proteinuria in pediatric chronic kidney disease progression? Evidence from the SP-CKD-Kids cohort

Abstract Background Hypertension and proteinuria are established risk factors for chronic kidney disease (CKD) progression in children. Given their pathophysiological interrelationship, whether their coexistence produces a multiplicative interaction remains uncertain. We evaluate...

Warming causes higher bilateral asymmetry in aquatic hemipterans from geothermal streams

Abstract Increase in temperature associated with climate change may alter community structure and disrupt developmental stability in ectothermic organisms. Using a natural geothermal gradient (20.6–40.3 °C) in Neotropical streams in central-western Brazil, we investigated how war...

HLA-DRB1 Polymorphisms Modulate the Dynamic Compatibility between the Presentation of EBNA1400–413 and MBP85–99

Abstract Multiple sclerosis (MS) shows a strong genetic association with HLA-DRB1 alleles and a consistent epidemiological association with Epstein–Barr virus (EBV) infection. However, it remains unclear how HLA-DRB1 polymorphisms modulate the presentation of autoantigens and vir...

Descriptive Histological and Histomorphometrical Comparison of Four Xenogeneic and Synthetic Bone Blocks for Mandibular Onlay Augmentation in Rabbits

Background: This exploratory study provided a primarily descriptive comparison of two xenogeneic and two synthetic blocks for mandibular onlay augmentation in rabbits. Methods: Twelve rabbits received bilateral block grafts, providing 24 sites allocated to Bio-Oss® Block, SP-Bloc...