Universidad de Buenos Aires

Composition determination of biodiesel/ethanol blends using dielectric spectroscopy and tabular prior-data fitted networks

Biodiesel/ethanol blends represent a promising alternative to reduce the consumption of fossil diesel. This work employs frequency-domain dielectric spectroscopy to determine the permittivity of biodiesel/ethanol blends across the full range of compositions, at temperatures betwe...

When Optimization Forgets the Minority: Bias Amplification in Policy-Gradient Reinforcement Learning

Bias amplification, the tendency of trained models to be more biased than the data that produced them, is well documented in supervised learning. We study it in policy-gradient reinforcement learning, where there is no static dataset: each episode belongs to a latent group that s...

Weaker Coherence, Weaker Reciprocity: Comparing the Semantic and Social Organization of Moltbook and Reddit

Large language models enable the creation of autonomous agents that interact in social environments, raising the question of whether agent-based platforms reproduce the organizational properties of human social networks. We compare Moltbook, a social network populated by AI agent...

Application of a Microfluidic Lab-on-a-Chip Platform Coupled with Automated Motility Analysis for Phenotypic Drug Screening of Trypanosoma cruzi Trypomastigotes

Chagas disease remains a major neglected tropical disease, highlighting the need for new anti-Trypanosoma cruzi compounds and improved approaches for their phenotypic evaluation. Here, we extended a previously developed Lab-on-a-Chip (LOC) platform integrating a serial dilution g...

Geography in the World Part 4: Towards Latin American Dialogues

ABSTRACT This fourth instalment of Geography in the World (GitW) aims to deepen engagement with geographical knowledge produced outside the Anglophone core—specifically, in Latin America—while reflecting on the practical challenges involved in doing so. The themed intervention co...

Does EQ-5D measure the most relevant aspects of health across cultures? Findings from a multi-country qualitative and card-sorting study

The EQ-5D is a widely used measure of health-related quality of life (HRQoL) in health services and economic evaluations globally. However, its cross-cultural content validity remains underexplored. This study assesses the relevance and adequacy of EQ-5D across diverse cultural c...

Testing Carbon-Input Feasibility in RothC Using Paired Soil Resampling over a 20-Year Interval in a Semi-Arid Steppe

Long-term soil organic carbon (SOC) monitoring provides a rare opportunity to test the performance of process-based models against real data. We evaluated RothC using 20 georeferenced soil profiles sampled in 2004 and 2024 in the semi-arid steppe of Central Kazakhstan. We used th...

Incorporating Advanced New or Recycled Materials in Reinforced Concrete Structures

Reinforced concrete continues to be one of the most widely used structural materials worldwide because of its versatility, availability, durability, and ability to accommodate a range of structural forms and loading conditions [...]

Mannose-Functionalized Polymeric Micelles Target CD206-Expressing Macrophages Within Human Tuberculosis Granulomas and Improve Isoniazid Delivery

Background: Latent tuberculosis infection (LTBI) remains a global health challenge, in part due to the ability of Mycobacterium tuberculosis (Mtb) to persist within granulomatous lesions where drug exposure may be limited. Because granulomas are heterogeneous structures composed...

What explains the implementation gap in foresight-designed policies? Evidence from a regional development strategy in Chile

Abstract Foresight and strategic planning have been widely recommended in public policy design to reduce uncertainty and improve governance. However, the gap between a foresight-designed public policy and its effective implementation remains a critical challenge for long-term gov...

Una aproximación cognitiva y construccional al fraseologismo rioplatense ¡Agarrate, Catalina (que vamos a galopar)!

Abstract This paper presents a corpus-based constructional study of the idiom ¡Agarrate, Catalina, que vamos a galopar! (literally ‘Hold on, Catalina, we’re going to gallop!’, meaning ‘Brace yourself!’), which is commonly used in Rioplatense Spanish to warn the interlocutor about...

Cycling Versus Swapping After First-Line TNF Inhibitor Failure in Psoriatic Arthritis: Real-World Insights From the Argentine RECCAPSO Registry

Objectives: Cycling within the same mechanism of action (MoA) or swapping to a different MoA are 2 strategies after failure of advanced therapy in psoriatic arthritis (PsA). We described the frequency, clinical characteristics, and treatment trajectory of cycling versus swapping...

Overlap of Subcutaneous Adiposity Across World Health Organization Body Mass Index-for-Age Categories and Anthropometric Correlates of Handgrip Strength in Children Aged 6–12 Years Participating in Organised Club Sport in Buenos Aires, Argentina

Background/Objectives: Body mass index (BMI) is the most widely used screening tool in paediatric nutritional assessment, but it does not measure body fat directly and conveys no information on muscular development. We aimed to (i) compare the sum of six skinfolds (Σ6ST) across W...

Bridging Gaps in Panthera leo Ethograms: A Systematic Review and Adaptable Model for Animal Welfare Research

Lions (Panthera leo) are keystone predators and an iconic species for wildlife conservation. Understanding their behaviour is critical for effective conservation strategies and for ensuring animal welfare in human-managed environments. Ethograms—systematic descriptions of behavio...

Life‑cycle analysis of bio‑based phase change materials in recycled‑aggregate mortars: sourcing sensitivity and trade‑offs

Abstract The decarbonization of construction materials requires circular design strategies supported by life‑cycle thinking. This study quantifies the cradle‑to‑gate (A1–A3) environmental impacts of three mortar formulations: (i) a Reference mortar, (ii) a mortar incorporating re...

S1 and S2 Are Positions, Not Signifiers: What Lacan Saw in the Möbius Cut

Lacan wrote that a signifier represents the subject for another signifier — S1 → S2 — and the subject is often pictured as a loop between S1 and S2. Read as a labelling of a closed chain, that picture has a flaw two crayons can expose: around a chain with an odd number of links,...

MicroRNAs as dynamic processors: from thresholding to temporal decoding

MicroRNAs are central regulators of gene expression. Traditionally viewed as static repressors of protein output, their regulatory role is increasingly recognized as inherently dynamic. In living systems, gene regulation unfolds far from equilibrium, where signals fluctuate over...

Mitochondrial Dysfunction Markers in Paediatric Obesity: DNA Content and Oxidation Damage

ABSTRACT Background Childhood obesity increases chronic disease risk. Mitochondrial dysfunction, reflected by altered mitochondrial DNA (mtDNA) content and oxidative damage, has been implicated in obesity‐related metabolic disorders, but paediatric data remain scarce. Objective T...

Angiotensin II and cAMP signaling pathways regulate mitochondrial biogenesis and activity in human adrenocortical cells

Abstract Mitochondrial homeostasis, governed by the balance between biogenesis and mitophagy, is essential for steroidogenesis in adrenocortical cells. While the requirement of active mitochondria for steroid synthesis is well-established, the hormonal regulation of genes governi...

Comparative effectiveness of stump closure methods during laparoscopic appendectomy: a systematic review and network meta-analysis of randomized controlled trials with CINeMA assessment

Laparoscopic appendectomy is one of the most performed emergency surgical procedures worldwide, and secure appendiceal stump closure remains a key step for ensuring favorable postoperative outcomes. Multiple closure techniques are currently available; however, comparative evidenc...