Universidad de Buenos Aires

Subchronic Cannabidiol (CBD) Treatment During the Silent Period Fails to Prevent Increased Seizure Susceptibility Following Lithium-Pilocarpine-Induced Status Epilepticus

Introduction. In recent years, cannabidiol (CBD) has been used as an adjunct therapy to anti-seizure medications for the control of seizures in patients with drug-resistant epilepsy. In addition to its anticonvulsant effect, CBD also has well-defined anti-inflammatory properties....

Neuropathological Effects of Early Maternal Separation are Prevented by CORT113176, A Glucocorticoid Receptor Modulator

Early-life stress, such as maternal separation (MS), disrupts the pup´s hypothalamic–pituitary–adrenal (HPA) axis and causes neuropathological changes in several nervous system regions, including the spinal cord. This damage is driven by glucocorticoid receptor (GR) overactivatio...

Expected redshift drift for tilted observers

Abstract Redshift drift is usually discussed for observers comoving with the cosmological background, but realistic observations are made by observers with nonzero peculiar motion. In this work, we calculate the expected redshift drift for tilted observers within the covariant 1...

eDNA Metabarcoding Reveals Spatial Patterns of Marine Communities Along the Beagle Channel (Tierra del Fuego, Argentina)

The Beagle Channel, located south of Tierra del Fuego (~54° S), is South America’s southernmost intracoastal ecosystem. Here, we applied environmental DNA metabarcoding using a partial sequence of the 12sRNA mitochondrial gene to evaluate the seasonal and spatial dynamics of mari...

FGFR3-driven gene regulatory network analysis reveals a protumoral role for p63 in luminal bladder tumors

Fibroblast growth factor receptor 3 ( FGFR3 ) is one of the most frequently altered genes in bladder cancer, primarily through activating mutations that drive oncogenesis and are enriched in luminal tumors. However, the underlying gene regulatory network (GRN) remains poorly char...

Adolescents’ Emotional Intelligence and Self-Perception in the Context of Social Media Use

This study examined the relationships between perceived emotional intelligence (EI), self-esteem, self-concept, and social media use in a sample of 173 Argentinian adolescents (mean age 16.6). Using the TMMS to assess three EI dimensions (attention, clarity, and mood repair) alon...