Umeå University

An additional water is introduced into the manganese cluster during the formation of the S3 state of photosystem II

During photosynthetic water oxidation, the Mn4Ca cluster in Photosystem II progresses through five intermediate Si (i = 0–4) states. X-ray crystallography studies have reported the insertion of one new O ligand during the formation of the S3 state, but recent studies question the...

Prediagnostic circulating 25-hydroxyvitamin D and prostate cancer-specific survival: a collaborative pooled analysis of 13 prospective studies

Abstract Background Previous research suggests higher risk of prostate cancer diagnosis in men with high vitamin D serology, but there are limited data related to prostate cancer survival. In this study, we examine the associations between prediagnostic circulating levels of 25-h...

Complementary strengths of the Neyman-Rubin and graphical causal frameworks

This article contributes to the discussion on the relationship between the Neyman-Rubin and the graphical frameworks for causal inference. We present specific examples of data-generating mechanisms — such as those involving undirected or deterministic relationships and cycles — w...

Trajectories of refraction and strabismus from 2.5 to 12 years in a national cohort of extremely preterm children‐ the Extremely Preterm Infants in Sweden Study (EXPRESS)

Abstract Purpose To investigate the longitudinal development of refraction and strabismus in a national cohort of children born extremely preterm (EPT) and find relations to perinatal events and neurodevelopmental outcomes. Methods All surviving children born <27‐gestation wee...

Enhancing psychological capital (PsyCap) to improve job satisfaction and retention: a pilot intervention study

Purpose This study aims to examine the effectiveness of a brief, structured intervention aimed at developing psychological capital (PsyCap) to enhance job satisfaction and reduce turnover intention. Grounded in the state–trait framework, the intervention treats PsyCap as a mallea...

Working with semantic machines: The role of semantic reconciliation in public sector data governance

Local governments are beginning to use artificial intelligence (AI) in internal administrative work, including recruitment. In a decentralized municipality, however, a standardized AI assessment must travel between a technology vendor, central HR specialists, recruiters, and hiri...

Small-sided games in floorball: impact on technical actions in players aged 7–18

Abstract Background Small-sided games (SSGs; modified match play with fewer players and a smaller pitch) are widely used in team sports to develop adaptable movement skills and decision-making in game-like contexts. However, evidence is limited on how different SSG formats affect...

Does cross-border regulatory cooperation reduce excessive risk-taking?

This study investigates how heightened regulatory scrutiny by the U.S. Securities and Exchange Commission (SEC), caused by the passage of the Multilateral Memorandum of Understanding (MMoU), affects excessive risk-taking by U.S. listed foreign firms. Using data from 37 countries...

Conserved dimerization architecture in C‐type lectins from virus‐vector mosquitoes

Abstract C-type lectins (CTLs) play key roles in innate immunity and microbial carbohydrate recognition. In the disease vector mosquito Aedes aegypti , the CTLD-S family comprises 34 soluble CTLs whose members are implicated in flavivirus dissemination and microbial homeostasis,...

Dimensionality, Reliability, and Validity of Academic Resilience Scales: A Systematic Review and Meta-analysis

Abstract Academic resilience refers to students’ capacity to maintain or regain adaptive academic functioning when confronted with academic stressors, setbacks, failure, or threat. Although the construct is often considered central to educational psychology, its psychometric foun...

Genome-wide association study of image-based emphysema scoring in the Swedish CArdioPulmonary bioImage Study (SCAPIS) suggests two new risk loci in smokers

Abstract Background Despite the high prevalence and clinical significance of emphysema, few genetic risk loci have been consistently replicated. We conducted a genome-wide association study (GWAS) of CT-based emphysema, with a particular focus on non-smoking-related genetic deter...

Inquiry, understanding, and the value of philosophy

Abstract In her article ‘A portrait of understanding as a non-factive state’ Ylwa Sjölin Wirling (2026) argues for the existence of an important but hitherto unnoticed form of understanding that she calls ‘non-factive objectual understanding’ (or NFOU for short). NFOU is the sort...

Understanding zoonotic spillover interfaces for the design of a One Health education intervention: a qualitative baseline study from rural Thailand

Abstract Background Prevention of zoonotic spillover requires an understanding of how human, animal, and environmental interactions shape risk in everyday life. Efforts have focused largely on surveillance and response rather than on primary prevention informed by lived experienc...

Towards Personalized Medicine in Chronic Kidney Disease: A Roadmap for the future of Early Detection, Diagnosis, and Management: A Consensus Roadmap from the EUTox, PerMedik and KidneyHealth networks

Chronic kidney disease (CKD) affects more than 800 million individuals worldwide and represents one of the fastest‑growing causes of morbidity and mortality. Despite major therapeutic advances, CKD is frequently detected only after substantial and irreversible loss of kidney func...

Impact of intraoperative CT on implant accuracy and reoperation rates in orbital floor reconstruction

BACKGROUND: Implant malposition is a leading cause of reoperation after orbital floor reconstruction. Intraoperative computed tomography (CT) enables immediate assessment and correction, however its impact on implant positioning accuracy and outcomes remains insufficiently studie...