Twin Cities Orthopedics

A Dynamic Auroral Ionospheric Density Profile Reveals a Planetary-Scale Cavity at Jupiter

Low-altitude measurements above Jupiter’s main auroras have shown the presence of persistent auroral density depletions. This low density regime strongly favors auroral acceleration by inertial Alfvén waves to explain the predominance of energetic (100–1000 keV) broadband electro...

Electron Transferto Colloidal ZnO Nanocrystals fromthe Excited State of a Perylene Chromophore Formed by Direct Excitationor Triplet–Triplet Annihilation Upconversion

Abstract Upon binding 4-(perylen-3-yl)benzoic acid 1, to oleate-capped ZnO nanocrystals (NCs), significant broadening of the perylene absorption spectrum and fluorescence quenching were observed. In contrast, no broadening of the absorption spectrum or fluorescence quenching was...

Unconventional BiocatalyticStrategies Orchestratethe Synthesis of the Nucleoside Analog Sinefungin

Abstract Sinefungin is a potent nucleoside antimetabolite of S-adenosylmethionine (SAM). Since its discovery in the 1970s, sinefungin has generated significant scientific interest owing to its role as a bioisostere of SAM and its broad range of biological activities. Despite cons...

Failing to Maintain Contact With Probation: Discovering the Reasons Why

A common requirement for individuals on probation is to remain in contact with their probation officer (PO). Failure to do these actions may result in a violation that could lead to a revocation. Further, not knowing one’s whereabouts on probation could create public safety conce...

Effects of early adulthood chronic sleep disruption on late life cognition, brain pathology, and microglial reactivity in the PS19 mouse model of tauopathy

Abstract A bidirectional relationship has been proposed between sleep and Alzheimer’s disease pathology, such that disruption to sleep can lead to increases in the expression of tau or its phosphorylation. Over the long term, this can potentially lead to greater expression of neu...