Shiraz University

A native dairy-derived Streptococcus thermophilus potentiates docetaxel efficacy by modulating apoptotic and PI3K/AKT/mTOR signaling pathways in MCF-7 breast cancer cells

Docetaxel (DTX) is a widely used chemotherapeutic agent for breast cancer; however, its clinical application is limited by dose-dependent toxicity and chemoresistance. This study investigated the chemosensitizing potential of a native dairy-derived S. thermophilus strain in combi...

Chemical sand control in hydrocarbon reservoirs: a comprehensive review of techniques, mechanisms, and field applications

Sand production is one of the most important problems in the unconsolidated or weakly consolidated sandstone formations that causes about 70% of hydrocarbon reservoirs in the world. Sand production results in some related problems, such as permeability impairment, wellbore instab...

Multimodal high-intensity interval training elicits greater improvements in aerobic capacity and sprint performance versus small-sided games and drill-based HIIT in adolescent basketball players: a randomized controlled trial

Traditional high-intensity interval training (HIIT) often lacks sport specificity, while small-sided games (SSG) may fail to isolate specific physiological qualities. Integrating both approaches could optimize training efficiency. Therefore, this study aimed to compare the effect...

Navigating the promise and perils of artificial intelligence in primary education: insights from the Iranian context

Purpose This study critically investigates the integration of artificial intelligence (AI) into Iranian primary education, highlighting both its transformative potential and context-specific challenges within a centralized and resource-constrained system. Design/methodology/appro...

Associations between sexual harassment experiences and attitudes toward marriage through social isolation among never married women in Shiraz, Iran

Abstract Marriage represents a central social and cultural institution in Iran, yet shifting gender norms, economic uncertainty, and exposure to social risks such as harassment may shape women’s attitudes toward marriage and life course decisions. This study examined the associat...

Sharing transparently: Caring for trustworthiness in qualitative data analysis in L2 research

Abstract The Open Science (OS) movement promotes transparency across the research process. This study examines how transparently qualitative data analysis is reported in second language (L2) research, where unclear methods can undermine trustworthiness. We conducted a qualitative...

Treatment of Licorice Wastewater via Coagulation–Flocculation and Ozonation Combination: ANN-GA Modeling and Optimization

This study aimed to remove licorice (Glycyrrhiza glabra) extract from pharmaceutical wastewater using a combination of treatment processes. An Artificial Neural Network (ANN) was coupled with a Genetic Algorithm (GA) to optimize the treatment parameters. Alum, polyaluminum chlori...

Improving digital soil mapping for imbalanced classes through feature selection and resampling

Abstract Accurate classification of imbalanced soil data remains a key challenge in Digital Soil Mapping (DSM). We propose a two-step preprocessing strategy that integrates feature selection with resampling to enhance soil class prediction. Using 140 soil profiles from the Darab...

Financial development, renewable energy, resource depletion, and energy security risk in D-8 countries

This study investigates the dynamic relationship among financial development, renewable energy consumption, natural resource depletion, and energy security risk in D-8 countries (Bangladesh, Egypt, Indonesia, Iran, Malaysia, Nigeria, Pakistan, and Turkey), a strategically importa...

A spatio-temporal analysis of the water–energy–food–environment nexus in Iran using a spatial econometric approach

Abstract Given Iran's location in a dry region and the serious challenges it faces regarding resource security, understanding the complex interactions between these four domains is essential for achieving sustainable development. Hence, this study analyzes the water-energy-food-e...

Linking phenotypic diversity to genomic hotspots using multi-environmental GWAS reveals genetic control of agronomic traits and drought resilience in wheat

Climate volatility demands wheat varieties with enhanced yield stability. Unraveling the genetic basis of stability, particularly genotype-by-environment (G × E) interactions, is critical in varirty development. We performed a high-resolution genetic analysis on 158 wheat recombi...

Susceptibility of Fig Cultivars to Thyrostroma parviniae , and Temperature-Dependent Pathogenicity on Potential Alternative Hosts

Thyrostroma parviniae has recently been identified as a dieback and bud-necrosis pathogen of fig trees in Iran. The resulting wood diseases pose a substantial challenge, given the current lack of effective and affordable treatment options. This study evaluates fig cultivar suscep...

Salinity stress alleviation in maize using endophytic fungi isolated from desert trees: physiological and biochemical responses

Soil salinization is a critical global challenge that limits agricultural productivity, particularly in arid and semi-arid regions. Endophytic fungi from extreme desert habitats offer a sustainable biological strategy to enhance crop salinity tolerance; however, their mechanistic...

Altered inter-joint coordination strategies of the lower extremity and pelvis in elite rowers with chronic low back pain

Rowing is a highly coordinated, cyclic task that requires efficient inter-joint coordination across the lower extremities and pelvis to optimize force transmission and performance. Chronic low back pain (CLBP) is prevalent among elite rowers and may alter neuromuscular control st...

Monitoring of oxidative stress and acute phase proteins following testes exposure with ultrasound waves in cats

Ultrasonic therapy has harmfully effects on the structure and function of the testis. Various mechanisms are involved in the impact of ultrasound waves on testes tissue. This study aimed to investigate the effects of ultrasound exposure on cat`s testes by monitoring acute phase p...

Predictors of academic self-efficacy in medical intern students: the roles of mindful eating, physical activity, sleep quality, and mental workload

Academic self-efficacy, defined as an individual’s belief in their capacity to complete academic tasks, may play a role in the learning and performance of medical students. Lifestyle factors such as sleep quality, physical activity, and mindfulness-based behaviors have been assoc...

Preconditioning by high-intensity interval training and moderate continuous training differentially affect hippocampal neurotrophic and inflammatory gene expression under acute noise stress in rats

Objectives This study compared high-intensity interval training (HIIT) versus moderate continuous training (MCT) as preconditioning on hippocampal BDNF, TrkB, and TNF-α gene expression in rats exposed to acute noise stress.Methods Forty-two male Wistar rats were randomised into s...

Efficacy evaluation of livestock-derived vermicompost in alleviating the adverse effects of drought stress on spinach growth and enhancing calcareous soil properties

Improving drought tolerance is essential to achieve high crop yields. Vermicomposting is a sustainable approach to enhance soil health, fertility, and water use efficiency, leading to higher crop yields. This study was conducted to investigate whether livestock vermicompost (V0 (...