Institution
Shenzhen University Health Science Center
Recent research
- Climate & Environment
Abstract Nonradical peroxymonosulfate (PMS) activation provides a selective route for micropollutant degradation, yet the orbital-level origin of oxidant speciation at single-atom sites remains unclear. Herein, an asymmetric Fe single-atom catalyst (Fe–N3–VN–C) is synthesized via...
- Health & MedicineOpen access
Uncertainty-inspired open-set model for identifying infantile fundus abnormalities
Accurate and safe identification of infantile fundus abnormalities is critical for large-scale screening, yet remains challenging because of heterogeneous disease presentations and overconfident predictions by conventional artificial intelligence (AI) models. In this study, we ai...
- BiologyOpen access
Abstract Background Diabetic cardiomyopathy (DCM) is defined by progressive cardiac dysfunction driven by myocardial ATP depletion, where mitochondrial electron transport chain (ETC) Complex I dysfunction acts as a critical factor. Protein arginine methyltransferase 5 (PRMT5) mai...
- Society & EconomicsOpen access
Violent crime is a widely recognized public health concern. According to emotion regulation theory, aggressive behavior in violent offenders is linked to maladaptive emotion regulation strategies. However, few studies have explored interventions targeting emotional factors to red...
- Health & MedicineOpen access
CAFs shape the immunosuppressive microenvironment of pancreatic cancer through the Lin28b-STING Axis
Cancer-associated fibroblasts comprise diverse functionally distinct cellular subsets, with certain subpopulations exerting pivotal influence in shaping the pancreatic cancer immune microenvironment. Here we show that Lin28b+ cancer-associated fibroblasts contribute to establishi...
- Health & MedicineOpen access
Early life sugar rationing and ageing related diseases, biological ageing and mortality
Early-life nutrition may influence lifelong ageing, yet human evidence is scarce. Using Britain’s postwar sugar rationing as a natural experiment, we examine its long-term effects in 64,809 United Kingdom Biobank participants. Exposure to sugar rationing during the first 1,000 da...