Royal College of Surgeons in Ireland

SKY92 Identifies High‐Risk Newly Diagnosed Multiple Myeloma With Inferior Progression‐Free Survival and Implicates NUF2 as a Candidate Driver

ABSTRACT Objectives To determine the prevalence and prognostic significance of the SKY92 gene‐expression signature, evaluate minimal/measurable residual disease (MRD), and identify molecular drivers of high‐risk disease in transplant‐eligible newly diagnosed multiple myeloma (TE‐...

Current Techniques for Inorganic Polyphosphate Detection and Characterisation

Polyphosphate (polyP) is an evolutionarily conserved linear polymer of orthophosphate residues with diverse functions across organisms from bacteria to mammals. In addition to its roles in phosphate and energy storage, polyP has been implicated in thrombosis, inflammation, cancer...

Team-Based Outpatient Rheumatology Care: A Scoping Review of Terminology, Team Composition, and Impact on Advancing the Quintuple Aim

Objectives Team-based models of rheumatology care, in which rheumatologists and interdisciplinary healthcare professionals (IHPs) collaborate in care delivery, are increasingly recognized to improve outcomes across all domains of the Quintuple Aim (population health, patient expe...