Palo Alto University

Three Views of Resolution in Carbon Markets Parsing Contractual, Regulatory and Atmospheric Claims

Abstract Carbon markets clear trades, enforce contracts, and satisfy regulatory obligations, yet atmospheric exposure remains open even where actors proceed in good faith. This article develops a typology of resolution—contractual, regulatory, and atmospheric—to explain why marke...

Chronic Invalidation: An Underexplored Source of Autistic Distress

Autistic people experience many symptoms of psychological distress at higher rates than non-autistic people and have limited tailored supports. Addressing the mental health needs of the Autistic community therefore represents a research, a clinical, and a societal imperative. Whi...

“My Existence is Queer”: Understanding Trans and Nonbinary College Students’ Sexual Identities

Scientific practices surrounding sexual identity are largely based upon cisheteronormative assumptions, using terms that may not resonate with − or may exclude − trans and nonbinary (TNB) individuals and their experiences. This exploratory study examined how TNB college students...

A database study of contemporary diagnosis and management among infants with congenital lung malformations in the United States

Congenital lung malformations (CLM) are commonly screened for on prenatal diagnostic testing and are an index pediatric surgical condition. Population-level contemporary data on incidence and management of CLMs in the United States remain limited. The objective was to evaluate th...

Critical Care Ultrasound-Guided Targeted Volume Management as Precision Medicine: Predicting Clinical and Financial Impacts

Precision medicine in the intensive care unit (ICU) is increasingly defined by individualized, bedside physiologic assessment rather than protocolized treatment algorithms. Critical care ultrasound for targeted volume management (CCUS-TVM) operationalizes this shift by helping cl...

Patterns of head and neck pain and obstructive sleep apnea in women with macromastia: A cross‐sectional analysis

Abstract Objectives/Background Symptomatic macromastia, or breast hypertrophy, is associated with musculoskeletal and neurological symptoms, including headache and neck pain. Though insurers list headache as an indication for breast reduction surgery, its relationship to specific...

The PancreaSure Multianalyte Blood Test Performs Well at Distinguishing Early-Stage Pancreatic Ductal Adenocarcinoma from High-Risk Controls: A Retrospective Secondary Analysis

Background/Objectives: Biomarkers that can facilitate early detection of pancreatic cancer and extend patient survival are a significant unmet need. PancreaSure is a serum biomarker signature that performed well at distinguishing Stage I and II pancreatic ductal adenocarcinoma (P...

Clinical Prediction With Time-Varying Predictors in Pediatric Hospital Medicine

Clinical prediction models traditionally rely on measurements obtained at a single time point to estimate risk and guide management. However, the clinical status of hospitalized children often evolves during admission, and time-varying measurements obtained over the course of hos...

Pivot Pedagogy: Stepping Through, Around, and Beyond the Permanence of Anti-Blackness from the WNBA to the Classroom

Abstract Both the WNBA and education are indebted to Black women, yet their contributions are obfuscated in botharenas. Women’s basketball is a key site where structural and cultural violence are inherent to, and reproduced through, socially constructed systems ofinequality, maki...

Evaluation of a National Mentorship Pilot Program for Early-Career Women in PHM

BACKGROUND: Women comprise most of the pediatric hospital medicine (PHM) workforce yet experience disparities in authorship, leadership, and compensation. Structured mentorship and professional development tailored to early-career women remain limited. Supporting Her in Navigatin...

Long-term Career Outcomes and Associations With Academic Careers, Leadership, and Publication Volume After Hand Fellowship

Background: We aimed to characterize career outcomes among fellowship-trained hand surgeons in the United States with a focus on academic careers and factors associated with leadership roles and post-fellowship publication volume. Methods: Of 94 programs in the American Society f...

The Orexin System—A Key Component of Sleep Regulatory Networks and Involvement in Narcolepsy

In this Perspective, 2026 Albert Lasker Basic Medical Research Award winners Emmanuel Mignot, MD, PhD, and Masashi Yanagisawa, MD, PhD, discuss their identification of the brain peptide orexin and how it relates to sleep, specifically orexin deficiency and narcolepsy.

Stage-dependent associations of glial fibrillary acidic protein and chitinase-3-like protein 1 with white matter network integrity in Alzheimer's disease

Background Astrocytes become reactive in Alzheimer's disease (AD), and fluid markers of this response, including glial fibrillary acidic protein (GFAP) and chitinase-3-like protein 1 (YKL-40), increase across the AD continuum. However, it remains unclear whether astrocytic biomar...

Implementing a Co-produced Curriculum for Neurodivergent Individuals in the Workplace

Individuals with intellectual and developmental disabilities (I/DD), especially autistic individuals, are disproportionately unemployed and underemployed. Job coaches (JCs), family members (FMs), and employers can serve as supports to improve employment outcomes of adults with I/...

Designing Social Media Health Warnings for Teenagers and Young Adults

Importance Social media use is nearly ubiquitous among US teenagers and young adults and has been associated with increased risk for negative health outcomes such as depression and anxiety. Policymakers in several states have proposed or adopted policies requiring warnings on soc...

Threatened Identity: Self Psychology Informed Communication for Serious Illness Care

Serious illness threatens both the body and the self: the coherent, continuous sense of who one is, from bodily integrity to psychosocial identity. When illness disrupts identity and patients confront mortality and dependence, a range of responses may follow, including behaviors...

Invariant splitting principles for the Lipshitz–Ozsváth–Thurston correspondence

Abstract We prove that the Lipshitz–Ozsváth–Thurston correspondence between extended type D structures of knot complements and knot Floer complexes can be arranged so that ‐invariant splittings of knot Floer chain complexes correspond to ‐invariant splittings of bordered Floer ho...

High-grade serous ovarian cancer is associated with increased TP53 mutation burden in uterine lavage

High grade serous ovarian cancer (HGSC) has low survival partly due to the lack of methods for detection, diagnosis, and risk prediction. TP53 mutations, which drive HGSC, are found in gynecological tissues as the result of somatic evolution, but it is unknown whether an excess o...

Testing the use of local large language models to extract trauma identification and contextualize posttraumatic stress symptoms from self-report

Abstract Accurate contextualization of trauma is critical for assessing posttraumatic stress disorder (PTSD) in behavioral health contexts, yet standard self-reports often fail to link symptoms to specific index traumas. This study evaluated the feasibility of using a local, priv...

Assessing physical activity and sleep patterns in glaucoma using wearable devices

Background/aims Glaucoma has been linked to reduced physical activity and disturbed sleep, but large-scale studies using objective wearable data are scarce. We compared activity and sleep metrics between adults with and without glaucoma using commercial wrist-worn devices. Method...