NYU Langone Health

A Retrospective Clinical Study of 44 Cases of Parapharyngeal Space Tumors

副咽頭間隙腫瘍はまれな疾患であり，治療方針の決定に苦慮することが多い。本検討では，手術適応の決定に関連する臨床因子を探索することを目的として，当院で診療した44例を後方視的に解析した。初回治療方針により手術群16例，経過観察群28例に分類し，性別，年齢，症状，腫瘍体積，腫瘍位置，FNAC施...

“Orthoplastic” Collaboration in fracture-related infection management reflects case complexity and is associated with achievable infection control

Background: The purpose of this study was to characterize fracture-related infection (FRI) cases requiring plastic surgery involvement and to evaluate infection-related outcomes in the setting of “orthoplastic collaboration.” Methods: A retrospective review was conducted of all p...

Spatially resolved tissue architecture and computational pathology in pancreatic cancer

Pancreatic ductal adenocarcinoma (PDAC) is a complex disease characterized by high levels of cellular heterogeneity and pronounced microenvironmental remodelling. Dynamic changes during its initiation and progression contribute to resistance to conventional therapies. Building up...

RAS inhibition limits oncogenic signaling and tumorigenesis in neuroblastoma regardless of RAS mutational status

Abstract Neuroblastoma (NBL) is a rare and aggressive pediatric malignancy with a 5-year survival rate of 40–50% for patients diagnosed with high-risk disease. NBLs arise in the sympathetic nervous system and causes 11% of all pediatric cancer deaths. MYCN amplification or overex...