Northern Border University

PLGA-loaded puerarin attenuates arsenic-induced liver injury through modulation of ferroptosis, oxidative stress, inflammation, and apoptotic signaling

Arsenic (AR) is an environmental and mining occupational toxicant with reported hepatotoxic effects. Ferroptosis has recently emerged as a critical mechanism involved in arsenic-induced hepatotoxicity. This study investigated the hepatoprotective effects of puerarin (PU) and its...

Rapid metaverse 3D assets generation via integration of neural rendering and physics based garment simulation

Production cycles are long, and the lack of realism in virtual content is a challenge in the metaverse industry, particularly for creating immersive experiences and generating a large number of 3D assets. The current approaches rely on neural rendering, which is not physically ac...

The Determinants of Sustainable Corporate Ecosystems: A Systematic Review

Sustainability challenges increasingly require ecosystem-based responses because economic, environmental, and social value is created across networks of interdependent organizations and stakeholders. Research on the determinants of sustainable corporate ecosystems (SCEs), however...

Norepinephrine Versus Vasopressin as First-Line Vasopressor Therapy in Septic Shock: Implications for Patients Presenting to the Emergency Department

Background: Septic shock requires rapid restoration of perfusion with infection treatment. Norepinephrine is the recommended initial vasopressor, while vasopressin offers an alternative mechanism of vascular support. This review examines comparative clinical outcomes and their re...

Polyhydroxy Molecular Regulator Enabled Interfacial Microenvironment Programming for Alkaline Zinc–Iron Flow Batteries

Abstract Alkaline zinc–iron flow batteries (ZIFBs) are attractive for large-scale energy storage because of their low cost, intrinsic safety, and scalable architecture, yet their practical deployment remains hindered by hydrogen evolution and uncontrolled Zn deposition in three-d...

Intelligent predictive neural network analysis on microbes in bioconvection flow of hybrid nanoliquid under diffusion thermo and thermo diffusion effects

The model optimizes microfluidic and lab-on-a-chip systems by predicting gyrotactic microbe-driven mixing and transport in the presence of linked thermal and concentration gradients. It aids in the design and operation of bioreactors and wastewater treatment units by simulating m...

Cadmium and bismuth dopants’ synergistic effect on the photocatalytic dye degradation potential of ZnO/CdO

Currently, several dyes are used in day-to-day activities, and their toxicity poses significant challenges to human health. In this study, the high negative conduction and positive valence band edge of zinc oxide (ZnO) were modified through the inclusion of Cd and Bi dopants as l...

Exploring the multifaceted therapeutic potential of linalool in triple negative breast cancer integrating in vitro, in silico, and network pharmacology approaches

A very aggressive type of breast cancer is triple-negative breast cancer (TNBC), leading to few treatment options, poor prognosis, and overall survival. The current trend in the application of natural compounds, especially essential oils, is an appropriate therapeutic approach wi...

Study of Cu3SbS4/Sb2S3 photothermal heterostructure coating for enhanced solar still desalination performance with durability analysis

Passive Solar Stills are an alternative method of producing fresh water in a decentralized manner. However, they suffer from being limited due to the low broadband solar absorptivity of typical basin materials. In this study we present the synthesis, characterization and photothe...

Geopolitical risks and value chain costs in Egypt and Saudi Arabia’s milling industry: the moderating effect of supply chain structure

Abstract This study empirically investigates how heightened geopolitical risks affect the value chain costs of upstream and downstream activities in Egyptian and Saudi milling firms from 2020 to 2025, and the moderating effect of supply chain structure. Grounded in resource depen...

Stereometric Molecular Engineering for Ultra‐Stable Aqueous Zinc‐Ion Batteries

ABSTRACT Aqueous zinc‐ion batteries (AZIBs) offer a safe and low‐cost energy storage platform yet are plagued by interfacial instability. Here, we investigate the relationship between molecular stereoisomerism and interfacial adsorption using inositol as a model system. Theoretic...

Trust calibration in human-AI collaborative decision-making: a cross-domain investigation of climate intelligence and organisational governance systems

Abstract The proliferation of artificial intelligence (AI) in complex decision environments has intensified scholarly and practical interest in how humans calibrate trust when collaborating with intelligent systems. This paper presents a cross-domain empirical investigation of hu...

LC–MS/MS Method for Simultaneous Quantification of Zolpidem, Zopiclone, and Their Metabolites in Human Urine and Its Pharmacokinetic Application

ABSTRACT Zolpidem (Z1) and zopiclone (Z2) are widely prescribed for insomnia; but their misuse in drug‐facilitated crimes presents significant forensic and clinical challenges. This study aimed to develop and validate a simple and sensitive LC–MS/MS method, coupled with dispersiv...

Pathways of Antimicrobial Resistance Emergence and Dissemination Associated with Biopharmaceutical Manufacturing

Antimicrobial resistance (AMR) is a worldwide One Health emergency, but the contribution of biotherapeutic manufacturing to the selection and dissemination of resistant microorganisms is not well appreciated. This review compiles available interdisciplinary evidence on biopharmac...

OSI Stack Redesign for Quantum Networks: Requirements, Technologies, Challenges, and Future Directions

Quantum communication is emerging as a foundation for next-generation networks, offering unprecedented capabilities in security, entanglement-based connectivity, and distributed computation. However, the classical Open Systems Interconnection (OSI) model, designed for determinist...

Computational identification of isoflavonoids as novel PPAR-γ agonists for the treatment of type 2 diabetes mellitus

Background The management of type 2 diabetes mellitus (T2DM) using peroxisome proliferator-activated receptor gamma (PPAR-γ) agonists is currently limited by the adverse effects of thiazolidinediones (TZDs), such as fluid retention and weight gain. This necessitates the search fo...

Unmasking the dark side: how does fossil fuel financing hurt the carbon neutrality targets?

The significance of carbon neutrality objectives in global climate mitigation efforts cannot be underestimated. Fossil fuels are widely believed to be a major culprit behind global climate change, and top polluting economies are still heavily investing in fossil fuels. Thus, the...

Thermoelectric ultra-high-performance geopolymer concrete containing nano carbon black: synergistic enhancement of mechanical, transport, and energy-harvesting performance

Ultra-high-performance geopolymer concrete (UHPGC) offers a sustainable alternative to conventional cement-based materials by combining lower carbon emissions with superior mechanical performance; however, its thermoelectric potential remains largely unexplored. This study evalua...

Seismic vulnerability and sustainable retrofit strategies for traditional masonry heritage buildings in Oman

Traditional masonry buildings constitute an important part of Oman’s architectural heritage; however, their seismic performance has received limited systematic attention despite the country’s exposure to regional and local seismic hazards. This study presents a qualitative assess...

Investigating the hydrogen storage potential and optoelectronic properties of double perovskite ZMg2FeH8 (Z = Ca, Be) hydrides

Abstract Hydrogen presents a compelling solution to the growing energy scarcity and environmental problems as a clean and sustainable energy source. Among various storage methods, solid-state hydrogen storage holds promise but necessitates extensive investigation. However, to enh...